Detection of traumatic brain injury with magnetic resonance imaging and S-100B protein in children, despite normal computed tomography of the brain

Pediatric Critical Care Medicine

Volumn 4, Issue 3, 2003, Pages 322-326

  Akhtar, Javed I ^a   Spear, Robert M ^a   Senac, Mel O ^a   Peterson, Bradley M ^a   Diaz, Susan M ^a  

^a RADY CHILDREN'S HOSPITAL   (United States)

Author keywords

Children; Computed tomography; Glasgow Coma Scale; Magnetic resonance imaging; S 100B protein; Traumatic brain injury

Indexed keywords

NERVE GROWTH FACTOR; PROTEIN S 100; S 100 CALCIUM BINDING PROTEIN BETA SUBUNIT; S-100 CALCIUM-BINDING PROTEIN BETA SUBUNIT;

ADOLESCENT; ARTICLE; BLOOD; BRAIN INJURY; CHILD; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; GLASGOW COMA SCALE; HUMAN; LENGTH OF STAY; MALE; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PILOT STUDY; PRESCHOOL CHILD; PROSPECTIVE STUDY; RADIOGRAPHY; STATISTICAL ANALYSIS;

ADOLESCENT; BRAIN INJURIES; CHILD; CHILD, PRESCHOOL; DATA INTERPRETATION, STATISTICAL; FEMALE; GLASGOW COMA SCALE; HUMANS; LENGTH OF STAY; MAGNETIC RESONANCE IMAGING; MALE; NERVE GROWTH FACTORS; PILOT PROJECTS; PROSPECTIVE STUDIES; S100 PROTEINS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0142217964     PISSN: 15297535     EISSN: 19473893     Source Type: Journal    
DOI: 10.1097/01.PCC.0000075323.47797.B8     Document Type: Article

References (40)

1. Gentry LR, Godersky JC, Thompson B, et al: MR imaging of head trauma: Review of the distribution and radiopathologic features of traumatic lesions. Am J Roentgenol 1988; 150:663-672
2. Orrison WW, Gentry LR, Stimac GK, et al: Blinded comparison of cranial CT and MR in closed head injury evaluation. AJNR 1994; 15:351-356
3. Kelly AB, Zimmerman RD, Snow RB, et al: Head trauma: Comparison of MR and CT- Experience in 100 patients. AJNR 1988; 9:699-708
4. Kuzma BB, Goodman JM: Improved identification of axonal shear injuries with gradient echo MR technique. Surg Neurol 2000; 53: 400-402
5. Doezema D, King JN, Tandberg D, et al: Magnetic resonance imaging in minor head injury. Ann Emerg Med 1991; 20:1281-1285
6. Han JS, Kaufman B, Alfidi RJ, et al: Head trauma evaluated by magnetic resonance and computed tomography: A comparison. Radiology 1984; 150:71-77
7. Liang L, Korogi Y, Sugahara T, et al: Detection of intracranial hemorrhage with susceptibility-weighted MR sequences. AJNR 1999; 20:1527-1534
8. Kruse A, Cesarini KG, Bach FW, et al: Increases of neuron-specific enolase, S-100 protein, creatine kinase and kinase BB isoenzyme in CSF following intraventricular catheter implantation. Acta Neurochir 1991; 110: 106-109
9. Herrmann M, Jost S, Kutz S, et al: Temporal profile of release of neurobiochemical markers of brain damage after traumatic brain injury is associated with intracranial pathology as demonstrated in cranial computerized tomography. J Neurotrauma 2000; 17: 113-122
10. Ingebrigtsen T, Waterloo K, Jacobsen EA, et al: Traumatic brain damage in minor head injury: Relation of serum S-100 protein measurements to magnetic resonance imaging and neurobehavioral outcome. Neurosurgery 1999; 45:468-475
11. Raabe A, Menon DK, Gupta S, et al: Jugular venous and arterial concentration of serum S-100B protein in patients with severe head injury: A pilot study. J Neurol Neurosurg Psychiatry 1998; 65:930-932
12. Elting JW, Jager A, Teelken AW, et al: Comparison of serum S-100 protein levels following stroke and traumatic brain injury. J Neurol Sci 2000; 181:104-110
13. Buttner T, Weyers S, Postert T, et al: S-100 protein: Serum marker of focal brain damage after ischemic territorial MCA infarction. Stroke 1997; 28:1961-1965
14. Blomquist S, Johnsson P, Luhrs C, et al: The appearance of S-100 protein in serum during and immediately after cardiopulmonary bypass surgery: A possible marker for cerebral injury. J Cardiothorac Vasc Anesth 1997; 11:699-703
15. Griffin WST, Stanley LC, Ling C, et al: Brain interleukin l and S-100 protein immunoreactivity are elevated in Down's syndrome and Alzheimer disease. Proc Natl Acad Sci U S A 1989; 86:7611-7615
16. Coene BD, Hajnal JV, Gatehouse P, et al: MR of the brain using fluid-attenuated inversion recovery (FLAIR) pulse sequences. AJNR 1992; 13:1555-1564
17. Ashikaga R, Araki Y, Ishida O, et al: MRI of head using FLAIR. Neuroradiology 1997; 39: 239-242
18. Wardlaw JM, Statham PFX: How often is haemosiderin not visible on routine MRI following traumatic intracerebral hemorrhage? Neuroradiology 2000; 42:81-84
19. Danna BZ, Emily HC, Aimee L, et al: The S-100 protein family: History, function, and expression. Brain Res Bull 1995; 37: 417-429
20. Lindberg L, Olsson AK, Anderson K, et al: Serum S-100 protein levels after pediatric cardiac operations: A possible new marker for postperfusion cerebral injury. J Thorac Cardiovasc Surg 1998; 116:281-285
21. Stuss DT, Ely P, Hugenholtz H, et al: Subtle neuropsychological deficits in patients with good recovery after closed head injury. Neurosurgery 1985; 17:41-47
22. Levin HS, Mattis S, Ruff RM, et al: Neurobehavioral outcome following minor head injury: A three-center study. J Neurosurg 1987; 66:234-243
23. Cicerone KD: Clinical sensitivity of four measures of attention to mild traumatic brain injury. Clin Neuropsychol 1997; 11:266-272
24. Arcia E, Gualtieri CT: Neurobehavioral performance of adults with closed head injury, adults with attention deficit, and control. Brain Inj 1994; 8:395-404
25. Levin HS, Song J, Scheibel RS, et al: Concept formation and problem solving following closed head injury in children. J Int Neuropsychol Soc 1997; 3:598-607
26. Romner B, Ingebrigtsen T, Kongstad P, et al: Traumatic brain damage: Serum S-100 protein measurements related to neuroradiological findings. J Neurotrauma 2000; 17:641-647
27. Anderson RE, Hansson LO, Nilsson O, et al: High serum S100B levels for trauma patients without head injuries. Neurosurgery 2001; 48:1255-1258
28. Haimoto H, Hosoda S, Kato K, et al: Differential distribution of immunoreactive S-100-alpha and S-100-beta proteins in normal nonnervous human tissues. Lab Invest 1987; 57:489-498
29. Deleted in proof
30. Deleted in proof
31. Nygaard O, Langbakk B, Romner B, et al: Age and sex related changes of S-100 protein concentrations in cerebrospinal fluid and serum in patients with no previous history of neurological disorder. Clin Chem 1997; 43: 541-543
32. Mittl RL, Grossman RI, Hiehle JF, et al: Prevalence of MR evidence of diffuse axonal injury in patients with mild head injury and normal head CT findings. AJNR 1994; 15: 1583-1589
33. Waterloo K, Ingebrigtsen T, Romner B, et al: Neuropsychological function in patients with increased serum levels of protein S-100 after minor head injury. Acta Neurochir 1997; 139:26-32
34. Shaaban A, Harmer M, Vaughan R, et al: Serum S-100 protein as a marker of cerebral damage during cardiac surgery. Review article. Br J Anesth 2000; 85:287-298
35. Hajnal JV, Bryant DJ, Kasuboski L, et al: Use of fluid-attenuated inversion recovery (FLAIR) pulse sequences in MRI of the brain. J Comput Assist Tomogr 1992; 16:841-844
36. Hans-Goran H, Nils E, Zbigniew K, et al: S-100 protein and neuron-specific enolase in CSF after experimental traumatic or focal ischemic brain damage. J Neurosurg 1989; 71:727-731
37. Lennart P, Hans-Goran H, Jorgen G, et al: S-100 protein and neuron-specific enolase in cerebrospinal fluid and serum: Markers of cell damage in human central nervous system. Stroke 1987; 18:911-918
38. McKeating EG, Andrews PJD, Mascia L, et al: Relationship of neuron specific enolase and S-100 protein concentrations in systemic and jugular venous serum to injury severity and outcome after traumatic brain injury. Acta Neurochir 1998; 71(Suppl):117-119
39. Woertgen C, Rothoerl RD, Holzschuh M, et al: Comparison of serial S-100 and NSE serum measurement after severe head injury. Acta Neurochir 1997; 139:1161-1165
40. Rothoerl RD, Brawanski A, Woertgen C, et al: S-100B protein levels after controlled cortical impact in the rat. Acta Neurochir 2000; 142:199-203