메뉴 건너뛰기




Volumn 12, Issue 1, 2003, Pages 1-7

CTLA4-Ig abrogates the anti-globulin response and prolongs cardiac allograft survival after anti-CD2 treatment

Author keywords

Anti CD2; Cardiac allograft survival; CTLA4 Ig; T cell depletion

Indexed keywords

CD2 ANTIGEN MONOCLONAL ANTIBODY; CD4 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; IMMUNOGLOBULIN ANTIBODY; INTERLEUKIN 2; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY OX34; MONOCLONAL ANTIBODY OX55; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG;

EID: 0142213315     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-3274(03)00061-3     Document Type: Article
Times cited : (7)

References (39)
  • 1
    • 0024472151 scopus 로고
    • Activation of T lymphocytes via monoclonal antibodies against rat cell surface antigens with particular reference to CD2 antigen
    • Beyers AD, Barclay AN, Law DA, He Q, Williams AF. Activation of T lymphocytes via monoclonal antibodies against rat cell surface antigens with particular reference to CD2 antigen. Immunol Rev 1989;111:59.
    • (1989) Immunol Rev , vol.111 , pp. 59
    • Beyers, A.D.1    Barclay, A.N.2    Law, D.A.3    He, Q.4    Williams, A.F.5
  • 2
    • 0024314938 scopus 로고
    • The CD2 antigen associates with the T-cell antigen receptor CD3 antigen complex on the surface of human T lymphocytes
    • Brown MH, Cantrell DA, Brattsand G, Crumpton MJ, Gullberg M. The CD2 antigen associates with the T-cell antigen receptor CD3 antigen complex on the surface of human T lymphocytes. Nature 1989;339(6225):551.
    • (1989) Nature , vol.339 , Issue.6225 , pp. 551
    • Brown, M.H.1    Cantrell, D.A.2    Brattsand, G.3    Crumpton, M.J.4    Gullberg, M.5
  • 3
    • 0021140557 scopus 로고
    • An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein
    • Meuer SC, Hussey RE, Fabbi M, et al. An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein. Cell 1984;36(4):897.
    • (1984) Cell , vol.36 , Issue.4 , pp. 897
    • Meuer, S.C.1    Hussey, R.E.2    Fabbi, M.3
  • 4
    • 0023894432 scopus 로고
    • Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation
    • Bierer BE, Barbosa J, Herrmann S, Burakoff SJ. Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation. J Immunol 1988;140(10):3358.
    • (1988) J Immunol , vol.140 , Issue.10 , pp. 3358
    • Bierer, B.E.1    Barbosa, J.2    Herrmann, S.3    Burakoff, S.J.4
  • 6
    • 0027310887 scopus 로고
    • Synergism between the CD3 antigen- and CD2 antigen-derived signals. Exploration at the level of induction of DNA-binding proteins and characterization of the inhibitory activity of cyclosporine
    • Sehajpal PK, Sharma VK, Ingulli E, Stenzel KH, Suthanthiran M. Synergism between the CD3 antigen- and CD2 antigen-derived signals. Exploration at the level of induction of DNA-binding proteins and characterization of the inhibitory activity of cyclosporine. Transplantation 1993;55(5):1118.
    • (1993) Transplantation , vol.55 , Issue.5 , pp. 1118
    • Sehajpal, P.K.1    Sharma, V.K.2    Ingulli, E.3    Stenzel, K.H.4    Suthanthiran, M.5
  • 7
    • 0027932728 scopus 로고
    • Human cell-adhesion molecule CD2 binds CD58 [LFA-3] with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59
    • van der Merwe PA, Barclay AN, Mason DW, et al. Human cell-adhesion molecule CD2 binds CD58 [LFA-3] with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59. Biochemistry 1994;33(33):10149.
    • (1994) Biochemistry , vol.33 , Issue.33 , pp. 10149
    • Van Der Merwe, P.A.1    Barclay, A.N.2    Mason, D.W.3
  • 8
    • 0025222529 scopus 로고
    • Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions
    • Nakamura T, Takahashi K, Fukazawa T, et al. Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions. J Immunol 1990;145(11):3628.
    • (1990) J Immunol , vol.145 , Issue.11 , pp. 3628
    • Nakamura, T.1    Takahashi, K.2    Fukazawa, T.3
  • 9
    • 0029930984 scopus 로고    scopus 로고
    • The structure and ligand interactions of CD2: Implications for T-cell function
    • Davis SJ, van der Merwe PA. The structure and ligand interactions of CD2: Implications for T-cell function. Immunol Today 1996;17(4):177.
    • (1996) Immunol Today , vol.17 , Issue.4 , pp. 177
    • Davis, S.J.1    Van Der Merwe, P.A.2
  • 10
    • 0026072162 scopus 로고
    • Induction of negative signal through CD2 during antigen-specific T cell activation
    • Ohno H, Nakamura T, Yagita H, Okumura K, Taniguchi M, Saito T. Induction of negative signal through CD2 during antigen-specific T cell activation. J Immunol 1991;147(7):2100.
    • (1991) J Immunol , vol.147 , Issue.7 , pp. 2100
    • Ohno, H.1    Nakamura, T.2    Yagita, H.3    Okumura, K.4    Taniguchi, M.5    Saito, T.6
  • 11
    • 0027163180 scopus 로고
    • Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses
    • Miller GT, Hochman PS, Meier W, et al. Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses. J Exp Med 1993;178(1):211.
    • (1993) J Exp Med , vol.178 , Issue.1 , pp. 211
    • Miller, G.T.1    Hochman, P.S.2    Meier, W.3
  • 12
    • 0029022778 scopus 로고
    • Involvement of cAMP in CD3 T cell receptor complex- and CD2-mediated apoptosis of human thymocytes
    • Mentz F, Mossalayi MD, Ouaaz F, Debre P. Involvement of cAMP in CD3 T cell receptor complex- and CD2-mediated apoptosis of human thymocytes. Eur J Immunol 1995;25(6):1798.
    • (1995) Eur J Immunol , vol.25 , Issue.6 , pp. 1798
    • Mentz, F.1    Mossalayi, M.D.2    Ouaaz, F.3    Debre, P.4
  • 13
    • 0030761214 scopus 로고    scopus 로고
    • CD2 induced apoptosis of peripheral T cells
    • Rouleau M, Mollereau B, Bernard A, et al. CD2 induced apoptosis of peripheral T cells. Transplant Proc 1997;29(5):2377.
    • (1997) Transplant Proc , vol.29 , Issue.5 , pp. 2377
    • Rouleau, M.1    Mollereau, B.2    Bernard, A.3
  • 14
    • 0029919954 scopus 로고    scopus 로고
    • CD2-induced apoptosis in activated human peripheral T cells: A Fas-independent pathway that requires early protein tyrosine phosphorylation
    • Mollereau B, Deckert M, Deas O, et al. CD2-induced apoptosis in activated human peripheral T cells: A Fas-independent pathway that requires early protein tyrosine phosphorylation. J Immunol 1996;156(9):3184.
    • (1996) J Immunol , vol.156 , Issue.9 , pp. 3184
    • Mollereau, B.1    Deckert, M.2    Deas, O.3
  • 15
    • 2642678473 scopus 로고    scopus 로고
    • Potent apoptotic signaling and subsequent unresponsiveness induced by a single CD2 mAb [BTI-322] in activated human peripheral T cells
    • Dumont C, Deas O, Mollereau B, et al. Potent apoptotic signaling and subsequent unresponsiveness induced by a single CD2 mAb [BTI-322] in activated human peripheral T cells. J Immunol 1998;160(8):3797.
    • (1998) J Immunol , vol.160 , Issue.8 , pp. 3797
    • Dumont, C.1    Deas, O.2    Mollereau, B.3
  • 17
    • 0031980631 scopus 로고    scopus 로고
    • Activation-induced NK cell death triggered by CD2 stimulation
    • Ida H, Anderson P. Activation-induced NK cell death triggered by CD2 stimulation. Eur J Immunol 1998;28(4):1292.
    • (1998) Eur J Immunol , vol.28 , Issue.4 , pp. 1292
    • Ida, H.1    Anderson, P.2
  • 18
    • 0025980207 scopus 로고
    • Anti-CD2 monoclonal antibodies alter cell-mediated immunity in vivo
    • Bromberg JS, Chavin KD, Altevogt P, et al. Anti-CD2 monoclonal antibodies alter cell-mediated immunity in vivo. Transplantation 1991;51(1):219.
    • (1991) Transplantation , vol.51 , Issue.1 , pp. 219
    • Bromberg, J.S.1    Chavin, K.D.2    Altevogt, P.3
  • 19
    • 0027467741 scopus 로고
    • Anti-CD2 and anti-CD3 monoclonal antibodies synergize to prolong allograft survival with decreased side effects
    • Chavin KD, Qin L, Lin J, Kaplan AJ, Bromberg JS. Anti-CD2 and anti-CD3 monoclonal antibodies synergize to prolong allograft survival with decreased side effects. Transplantation 1993;55(4):901.
    • (1993) Transplantation , vol.55 , Issue.4 , pp. 901
    • Chavin, K.D.1    Qin, L.2    Lin, J.3    Kaplan, A.J.4    Bromberg, J.S.5
  • 20
    • 0028135078 scopus 로고
    • CTLA4Ig prolongs allograft survival while suppressing cell-mediated immunity
    • Baliga P, Chavin KD, Qin L, et al. CTLA4Ig prolongs allograft survival while suppressing cell-mediated immunity. Transplantation 1994;58(10):1082.
    • (1994) Transplantation , vol.58 , Issue.10 , pp. 1082
    • Baliga, P.1    Chavin, K.D.2    Qin, L.3
  • 21
    • 0036705293 scopus 로고    scopus 로고
    • CD2 is a dominant target for allogeneic responses
    • Bai Y, Fu S, Honig S, et al. CD2 is a dominant target for allogeneic responses. Am J Transplant 2002;2(7):618.
    • (2002) Am J Transplant , vol.2 , Issue.7 , pp. 618
    • Bai, Y.1    Fu, S.2    Honig, S.3
  • 22
    • 0029851220 scopus 로고    scopus 로고
    • Blockade of multiple costimulatory receptors induces hyporesponsiveness: Inhibition of CD2 plus CD28 pathways
    • Woodward JE, Qin L, Chavin KD, et al. Blockade of multiple costimulatory receptors induces hyporesponsiveness: Inhibition of CD2 plus CD28 pathways. Transplantation 1996;62(7):1011.
    • (1996) Transplantation , vol.62 , Issue.7 , pp. 1011
    • Woodward, J.E.1    Qin, L.2    Chavin, K.D.3
  • 23
    • 0031586556 scopus 로고    scopus 로고
    • Modulation of the CD2 receptor and not disruption of the CD2/CD48 interaction is the principal action of CD2-mediated immunosuppression in the rat
    • Sido B, Otto G, Zimmermann R, Muller P, Meuer SC, Dengler TJ. Modulation of the CD2 receptor and not disruption of the CD2/CD48 interaction is the principal action of CD2-mediated immunosuppression in the rat. Cell Immunol 1997;182(1):57.
    • (1997) Cell Immunol , vol.182 , Issue.1 , pp. 57
    • Sido, B.1    Otto, G.2    Zimmermann, R.3    Muller, P.4    Meuer, S.C.5    Dengler, T.J.6
  • 24
    • 0031959822 scopus 로고    scopus 로고
    • Differential immunosuppressive activity of monoclonal CD2 antibodies on allograft rejection vs. specific antibody production
    • Sido B, Dengler TJ, Otto G, Zimmermann R, Muller P, Meuer SC. Differential immunosuppressive activity of monoclonal CD2 antibodies on allograft rejection vs. specific antibody production. Eur J Immunol 1998;28(4):1347.
    • (1998) Eur J Immunol , vol.28 , Issue.4 , pp. 1347
    • Sido, B.1    Dengler, T.J.2    Otto, G.3    Zimmermann, R.4    Muller, P.5    Meuer, S.C.6
  • 25
    • 0014468579 scopus 로고
    • Improved technique of heart transplantation in rats
    • Ono K, Lindsey ES. Improved technique of heart transplantation in rats. J Thorac Cardiovasc Surg 1969;57(2):225.
    • (1969) J Thorac Cardiovasc Surg , vol.57 , Issue.2 , pp. 225
    • Ono, K.1    Lindsey, E.S.2
  • 26
    • 0026059140 scopus 로고
    • Structure of domain 1 of rat T lymphocyte CD2 antigen
    • [see comments]
    • Driscoll PC, Cyster JG, Campbell ID, Williams AF. Structure of domain 1 of rat T lymphocyte CD2 antigen [see comments]. Nature 1991;353(6346):762.
    • (1991) Nature , vol.353 , Issue.6346 , pp. 762
    • Driscoll, P.C.1    Cyster, J.G.2    Campbell, I.D.3    Williams, A.F.4
  • 27
    • 0025963594 scopus 로고
    • Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
    • Linsley PS, Brady W, Grosmaire L, Aruffo A, Damle NK, Ledbetter JA. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J Exp Med 1991;173(3):721.
    • (1991) J Exp Med , vol.173 , Issue.3 , pp. 721
    • Linsley, P.S.1    Brady, W.2    Grosmaire, L.3    Aruffo, A.4    Damle, N.K.5    Ledbetter, J.A.6
  • 28
    • 0032573414 scopus 로고    scopus 로고
    • Thymus-dependent, anti-CD4-induced tolerance to rat cardiac allografts
    • Jaques BC, Ahmiedat H, Alastair Gracie J, et al. Thymus-dependent, anti-CD4-induced tolerance to rat cardiac allografts. Transplantation 1998;66(10):1291.
    • (1998) Transplantation , vol.66 , Issue.10 , pp. 1291
    • Jaques, B.C.1    Ahmiedat, H.2    Alastair Gracie, J.3
  • 29
    • 0024490423 scopus 로고
    • A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes
    • Hunig T, Wallny HJ, Hartley JK, Lawetzky A, Tiefenthaler G. A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes. J Exp Med 1989;169(1):73.
    • (1989) J Exp Med , vol.169 , Issue.1 , pp. 73
    • Hunig, T.1    Wallny, H.J.2    Hartley, J.K.3    Lawetzky, A.4    Tiefenthaler, G.5
  • 30
    • 0021984604 scopus 로고
    • Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor
    • O'Flynn K, Krensky AM, Beverley PC, Burakoff SJ, Linch DC. Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor. Nature 1985;313(6004):686.
    • (1985) Nature , vol.313 , Issue.6004 , pp. 686
    • O'Flynn, K.1    Krensky, A.M.2    Beverley, P.C.3    Burakoff, S.J.4    Linch, D.C.5
  • 31
    • 0028214483 scopus 로고
    • Specific down regulation of proliferative T cell alloresponsiveness by interference with CD2/LFA-3 and LFA-1/ICAM-1 in vitro
    • Bohmig G, Kovarik J, Holter W, Pohanka E, Zlabinger G. Specific down regulation of proliferative T cell alloresponsiveness by interference with CD2/LFA-3 and LFA-1/ICAM-1 in vitro. J Immunol 1994;152:3720.
    • (1994) J Immunol , vol.152 , pp. 3720
    • Bohmig, G.1    Kovarik, J.2    Holter, W.3    Pohanka, E.4    Zlabinger, G.5
  • 32
    • 0029608872 scopus 로고
    • A sensitive assay for detecting low-affinity interactions at the cell surface reveals no additional ligands for the adhesion pair rat CD2 and CD48
    • Brown MH, Preston S, Barclay AN. A sensitive assay for detecting low-affinity interactions at the cell surface reveals no additional ligands for the adhesion pair rat CD2 and CD48. Eur J Immunol 1995;25(12):3222.
    • (1995) Eur J Immunol , vol.25 , Issue.12 , pp. 3222
    • Brown, M.H.1    Preston, S.2    Barclay, A.N.3
  • 33
    • 0028123444 scopus 로고
    • CD28-mediated costimulation of interleukin 2 [IL-2] production plays a critical role in T cell priming for IL-4 and interferon gamma production
    • Seder RA, Germain RN, Linsley PS, Paul WE. CD28-mediated costimulation of interleukin 2 [IL-2] production plays a critical role in T cell priming for IL-4 and interferon gamma production. J Exp Med 1994;179(1):299.
    • (1994) J Exp Med , vol.179 , Issue.1 , pp. 299
    • Seder, R.A.1    Germain, R.N.2    Linsley, P.S.3    Paul, W.E.4
  • 34
    • 0027281691 scopus 로고
    • Differential T cell costimulatory requirements in CD28-deficient mice
    • Shahinian A, Pfeffer K, Lee KP, et al. Differential T cell costimulatory requirements in CD28-deficient mice. Science 1993;261(5121):609.
    • (1993) Science , vol.261 , Issue.5121 , pp. 609
    • Shahinian, A.1    Pfeffer, K.2    Lee, K.P.3
  • 35
    • 0026738641 scopus 로고
    • Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4Ig
    • [see comments]
    • Lenschow DJ, Zeng Y, Thistlethwaite JR, et al. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4Ig [see comments]. Science 1992;257(5071):789.
    • (1992) Science , vol.257 , Issue.5071 , pp. 789
    • Lenschow, D.J.1    Zeng, Y.2    Thistlethwaite, J.R.3
  • 36
    • 0028055141 scopus 로고
    • Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo
    • Ronchese F, Hausmann B, Hubele S, Lane P. Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo. J Exp Med 1994;179(3):809.
    • (1994) J Exp Med , vol.179 , Issue.3 , pp. 809
    • Ronchese, F.1    Hausmann, B.2    Hubele, S.3    Lane, P.4
  • 37
    • 0029062081 scopus 로고
    • Identification of the TS2/18-recognized epitope on the CD2 molecule as a target for suppression of T cell cytokine synthesis
    • Schwarz M, Bohuslav J, Majdic O, Stockinger H, Knapp W, Holter W. Identification of the TS2/18-recognized epitope on the CD2 molecule as a target for suppression of T cell cytokine synthesis. J Immunol 1995;154(11):5813.
    • (1995) J Immunol , vol.154 , Issue.11 , pp. 5813
    • Schwarz, M.1    Bohuslav, J.2    Majdic, O.3    Stockinger, H.4    Knapp, W.5    Holter, W.6
  • 38
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
    • Boise LH, Minn AJ, Noel PJ, et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 1995;3(1):87.
    • (1995) Immunity , vol.3 , Issue.1 , pp. 87
    • Boise, L.H.1    Minn, A.J.2    Noel, P.J.3
  • 39
    • 0030006733 scopus 로고    scopus 로고
    • CD28 costimulation prevents cell death during primary T cell activation
    • Noel PJ, Boise LH, Green JM, Thompson CB. CD28 costimulation prevents cell death during primary T cell activation. J Immunol 1996;157(2):636.
    • (1996) J Immunol , vol.157 , Issue.2 , pp. 636
    • Noel, P.J.1    Boise, L.H.2    Green, J.M.3    Thompson, C.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.