Using O-(n-alkyl)-N-(N,N′-dimethylethyl)phosphoramidates to investigate the role of Ca2+ and interfacial binding in a bacterial phospholipase D

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1649, Issue 2, 2003, Pages 146-153

  Oh, Mi Kyung ^a   Yang, Hongying ^a   Roberts, Mary F ^a  

^a BOSTON COLLEGE   (United States)

Author keywords

Kinetic; Phospholipase D; Phosphoramidate inhibitor; Vesicle binding

Indexed keywords

BACTERIAL ENZYME; CABBAGE PHOSPHOLIPIDASE D; CALCIUM; MONOMER; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE D; PHOSPHORAMIDIC ACID DERIVATIVE; STREPTOMYCES CHROMOFUSCUS PHOSPHOLIPIDASE D; STREPTOMYCES PMF PHOSPHOLIPIDASE D; UNCLASSIFIED DRUG; AMIDE; ENZYME INHIBITOR; PHOSPHORAMIDIC ACID; PHOSPHORIC ACID; RECOMBINANT PROTEIN;

ARTICLE; BILAYER MEMBRANE; BINDING AFFINITY; CALCIUM BINDING; CATALYSIS; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANALYSIS; DRUG BINDING SITE; DRUG BIOAVAILABILITY; DRUG POTENCY; DRUG SENSITIVITY; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME SUBSTRATE; MICELLE; NONHUMAN; PRIORITY JOURNAL; SOLUBILITY; STREPTOMYCES; BINDING SITE; BRASSICA; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; METABOLISM; SYNTHESIS;

BACTERIA (MICROORGANISMS); BRASSICA OLERACEA VAR. CAPITATA; STREPTOMYCES; STREPTOMYCES CHROMOFUSCUS; STREPTOMYCES SP.; STREPTOMYCES SP. PMF;

AMIDES; BINDING SITES; BRASSICA; CALCIUM; ENZYME INHIBITORS; MOLECULAR STRUCTURE; PHOSPHATIDYLCHOLINES; PHOSPHOLIPASE D; PHOSPHORIC ACIDS; RECOMBINANT PROTEINS; STREPTOMYCES;

EID: 0142183351     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-9639(03)00166-3     Document Type: Article

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