Cyclosporine C2-Monitoring for Optimisation of Immunosuppression in Renal Transplantation - Recommendations According to First Experience in German Centers;Cyclosporin C2-Monitoring zur Optimierung der Immunsuppression nach Nierentransplantation - Empfehlungen anhand Erster Erfahrungen in Deutschland

Transplantationsmedizin: Organ der Deutschen Transplantationsgesellschaft

Volumn 15, Issue 1, 2003, Pages 15-24

  Nashan, Björn ^a   Armstrong, V W ^f   Budde, K ^b   Fricke, L ^f   Heemann, U ^f   Luck R ^a   Rothele E ^c   Scheuermann, E H ^d   Suwelack, B ^e  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

^d UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^e UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^f NONE

Author keywords

C2 monitoring; Cyclosporine microemulsion; Renal transplantation; Therapeutic monitoring

Indexed keywords

CYCLOSPORIN A; CYCLOSPORIN C;

ACUTE GRAFT REJECTION; CHRONIC GRAFT REJECTION; CONFERENCE PAPER; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG EXPOSURE; DRUG FORMULATION; DRUG MONITORING; EUROPE; GERMANY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; MICROEMULSION; RECIPIENT;

EID: 0142167605     PISSN: 09469648     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (13)

1. Amstrong VW (2002) Principles and practice of monitoring immunosuppressive drugs. J Lab Med 26: 27-36
2. Belitsky P et al. (2000) Neoral absorption profiling: an evolution in effectiveness. Transplantation Proceedings 32 (suppl 3A): 45-52
3. Cantarovich M et al. (1998) Two-hour cyclosporin level determination is the appropriate tool to monitor Neoral therapy. Clin Transplant 12: 243-249
4. 2 levels and exposure in de novo and maintenance pediatric liver transplant recipients. Am J Transplant 1 (suppl): 419
5. Halloran PF et al. (1999) The temporal profile of calcineurin inhibition by cyclosporin in vivo. Transplantation 68: 1356-1361
6. 2 levels is predictive for AUC in lung transplant recipients. J Heart Lung Transplant 21: 87
7. Johnston A et al. (2000) Pharmacokinetic Validation of Neoral Absorption Profiling. Transplantation Proceedings, 32 (suppl 3A): 53-56
8. Kelles A et al. (1999) Sandimmune to Neoral conversion and value of abbreviated AUC monitoring in stable pediatric kidney transplant recipients. Pediatr Transplant 3: 283-287
9. 2 monitoring: An international consensus statement. Transplantation 73 (suppl): 12-18
10. 2 monitoring strategy for optimising cyclosporin immunosuppression from from the Neoral formulation Biodrugs 15 (suppl 5): 279-290
11. Mahalati K et al. (1999) Neoral monitoring by simplified sparse sampling area under the concentration-time curve. Transplantation 68: 55-62
12. 2 monitoring: A review. Transplantation 73 (suppl): 3-11
13. Toselli L et al. (2002) Minimal rejection and excellent graft function by Neoral C2 monitoring in renal transplantation: Interim results of MO2ART, a randomised prospective international study. Presented at XIX International Congress of Transplantation Society, Miami/USA. Abstract 2377