Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase to elucidate the role of serine 103 for enzymatic activity

FEBS Letters

Volumn 454, Issue 1-2, 1999, Pages 142-146

  Grädler, Ulrich ^a   Ficner, Ralf ^a   Garcia, George A ^b   Stubbs, Milton T ^a   Klebe, Gerhard ^a   Reuter, Klaus ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Catalytic mechanism; Crystal structure; Modified nucleoside; Queuine; tRNA

Indexed keywords

ALANINE; GLYCOSYLTRANSFERASE; GUANINE; MUTANT PROTEIN; QUEUINE; SERINE; TRANSFER RNA;

AMINO ACID SUBSTITUTION; ANTICODON; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY; ZYMOMONAS MOBILIS;

CRYSTALLOGRAPHY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GUANINE; MOLECULAR STRUCTURE; MUTAGENESIS; PENTOSYLTRANSFERASES; SERINE; ZYMOMONAS;

ESCHERICHIA COLI; ZYMOMONAS MOBILIS;

EID: 0142159351     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)00793-0     Document Type: Article

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