Righting the wrongs. DNA and protein sequence databases are increasingly useful research tools. But to maximize their potential, the errors in them need to be addressed

EMBO Reports

Volumn 4, Issue 9, 2003, Pages 829-831

  Hadley, Caroline ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GENE PRODUCT; PROTEIN;

ACCURACY; AMINO ACID SEQUENCE; ARTICLE; DNA DATA BANK OF JAPAN; DNA SEQUENCE; EMBL NUCLEOTIDE SEQUENCE DATABASE; ERROR; GENBANK; GENE IDENTIFICATION; GENOME; MEDICAL RESEARCH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN STRUCTURE; RELIABILITY; SEQUENCE DATABASE; SWISS-PROT; TECHNOLOGY; ALGORITHM; ARTIFACT; BIOINFORMATICS; COMPUTER; HUMAN; MYCOPLASMA GENITALIUM; NONHUMAN; RESEARCH; NUCLEIC ACID DATABASE; PROTEIN DATABASE; STANDARD;

DATABASES, NUCLEIC ACID; DATABASES, PROTEIN;

EID: 0142155182     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.embor932     Document Type: Article

References (10)

1. Árnason, E. (2003) Genetic heterogeneity of Icelanders. Ann. Hum. Genet., 67, 5-16.
2. Brenner, S.E. (1999) Errors in genome annotation. Trends Genet., 15, 132-133.
3. CODATA Task Group on Biological Macromolecules and Colleagues (2000) Quality control in databanks for molecular biology. Bioessays, 22, 1024-1034.
4. Forster, P. (2003) To err is human. Ann. Hum. Genet., 67, 2-4.
5. Gene Ontology Consortium (2000) Gene ontology: tool for the unification of biology. Nature Genet., 25, 25-29.
6. Gilks, W.R., Audit, B., De Angelis, D., Tsoka, S. & Ouzounis, C.A. (2003) Modeling the percolation of annotation errors in a database of protein sequences. Bioinformatics, 18, 1641-1649.
7. Kyrpides, N.C. & Ouzounis, C.A. (1999) Whole-genome sequence annotation: going wrong with confidence. Mol. Microbiol., 32, 886-887.
8. Röhl, A., Brinkmann, B., Forster, L. & Forster, P. (2001) An annotated mtDNA database. Int. J. Legal Med., 115, 29-39.
9. Sekyere, E., Dunn, L.L. & Richardson, D.R. (2003) The double-edged nature of using genetic databases: melanotransferrin genes and transcripts. FEBS Lett., 547, 233.
10. Willerslev, E., Mourier, T., Hansen, A.J., Christensen, B., Barnes, I. & Salzberg, S.L. (2002) Contamination in the draft of the human genome masquerades as lateral gene transfer. DNA Seq., 13, 75-76.