Abnormal heart rate recovery immediately after treadmill testing: Correlation with clinical exercise testing, and myocardial perfusion parameters

Journal of Nuclear Cardiology

Volumn 10, Issue 5, 2003, Pages 498-505

  Georgoulias, Panagiotis ^a,c   Orfanakis, Alexandros ^b   Demakopoulos, Nikolaos ^a   Xaplanteris, Petros ^a   Mortzos, Georgios ^a   Vardas, Panos ^b   Karkavitsas, Nikolaos ^b  

^a NIMTS HOSPITAL   (Greece)

^b UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

^c NONE   (Greece)

Author keywords

Heart rate recovery; Myocardial ischemia; Myocardial perfusion imaging; Treadmill testing

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; NITRATE; TETROFOSMIN TC 99M; THALLIUM 201;

ADRENERGIC TRANSMISSION; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CARDIOVASCULAR RISK; CHOLINERGIC SYSTEM; CHRONOTROPISM; CLINICAL EXAMINATION; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORRELATION ANALYSIS; DISEASE SEVERITY; DRUG USE; EXERCISE TEST; FEMALE; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART RATE; HEART SCINTISCANNING; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; QUANTITATIVE ANALYSIS; RATING SCALE; RELIABILITY; SEX DIFFERENCE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STATISTICAL ANALYSIS; TREADMILL EXERCISE;

EID: 0142151035     PISSN: 10713581     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-3581(03)00530-0     Document Type: Article

References (24)

1. Barron HV, Lesh MD. Autonomic nervous system and sudden cardiac death. J Am Coll Cardiol 1996;27:1053-6.
2. Sandvik L, Erikssen J, Ellestad M, et al. Heart rate increase and maximal heart rate during exercise as predictors of cardiovascular mortality: a 16-year follow-up study of 1960 healthy men. Coron Artery Dis 1995;6:667-7, 1996.
3. Schwartz PJ, La Rovere MT, Vanoli E. Autonomic nervous system and sudden cardiac death. Experimental basis and clinical observations for post-myocardial infarction risk stratification. Circulation 1992;85:177-91.
4. Ellestad MH. Chronotropic incompetence. The implications of heart rate response to exercise (compensatory parasympathetic hyperactivity?). Circulation 1996;93:1485-7.
5. Arai Y, Saul JP, Albrecht P, et al. Modulation of cardiac autonomic activity during and immediately after exercise. Am J Physiol 1989;256:H132-41.
6. Imai K, Sato H, Hori M, et al. Vagally mediated heart rate recovery after exercise is accelerated in athletes but blunted in patients with chronic heart failure. J Am Coll Cardiol 1994;24:1529-35.
7. Fletcher GF, Balady G, Froelicher VF, et al. Exercise standards. A statement for healthcare professionals from the American Heart Association Writing Group. Circulation 1995;91:580-615.
8. Lauer MS, Francis GS, Okin PM, et al. Impaired chronotropic response to exercise stress testing as a predictor of mortality. JAMA 1999;281:524-9.
9. Cole CR, Blackstone EH, Pashkow FJ, Snader CE, Lauer MS. Heart-rate recovery immediately after exercise as a predictor of mortality. N Engl J Med 1999;341:1351-7.
10. Desai MY, De La Pena-Almaguer E, Mannting F. Abnormal heart rate recovery after exercise: a comparison with known indicators of increased mortality. Cardiology 2001;96:38-44.
11. Cole CR, Foody JM, Blackstone EH, Lauer MS. Heart rate recovery after submaximal exercise testing as a predictor of mortality in a cardiovascularly healthy cohort. Ann Intern Med 2000;132:552-5.
12. Kurata C, Tawarahara K, Taguchi T, et al. Lung thallium-201 uptake during exercise emission computed tomography. J Nucl Med 1991;32:417-23.
13. Georgoulias P, Demakopoulos N, Kontos A, et al. Tc-99m tetrofosmin myocardial perfusion imaging before and six months after percutaneous transluminal coronary angioplasty. Clin Nucl Med 1998;23:678-82.
14. mTc-tetrofosmin myocardial perfusion imaging: a comparison with coronary angiography [in German]. Nuklearmedizin 1996;35:153-5.
15. Aepfelbacher FC, Johnson RB, Schwartz JG, et al. Validation of a model of left ventricular segmentation for interpretation of SPET myocardial perfusion images. Eur J Nucl Med 2001;28: 1624-9.
16. Watanabe J, Thamilarasan M, Blackstone EH, Thomas JD, Lauer MS. Heart rate recovery immediately after treadmill exercise and left ventricular systolic dysfunction as predictors of mortality; the case of stress echocardiography. Circulation 2001;104:1911-6.
17. Nishime EO, Cole CR, Blackstone EH, Pashkow FJ, Lauer MS. Heart rate recovery and treadmill exercise score as predictors of mortality in patients referred for exercise ECG. JAMA 2000;284:1392-8.
18. Rigo P, Leclercq B, Itti R, Lahiri A, Braat S. Technetium-99m-tetrofosmin myocardial imaging: a comparison with thallium-201 and angiography. J Nucl Med 1994;35:587-93.
19. Iskandrian AS, Chae SC, Heo J, et al. Independent and incremental prognostic value of exercise single-photon emission computed tomographic (SPECT) thallium imaging in coronary artery disease. J Am Coll Cardiol 1993;22:665-70.
20. Brown KA, Altland E, Rowen M. Prognostic value of normal technetium-99m-sestamibi cardiac imaging. J Nucl Med 1994;35: 554-7.
21. Brown KA. Prognostic value of thallium-201 myocardial perfusion imaging. A diagnostic tool comes of age. Circulation 1991;83:363-81.
22. Osterhues HH, Kochs M, Hombach V. Time-dependent changes of heart rate variability after percutaneous transluminal angioplasty. Am Heart J 1998;135:755-61.
23. Grunwald AM, Watson DD, Holzgrefe HH Jr, Irving JF, Beller GA. Myocardial thallium-201 kinetics in normal and ischemic myocardium. Circulation 1981;64:610-8.
24. Sridhara BS, Braat S, Rigo P, et al. Comparison of myocardial perfusion imaging with technetium-99m tetrofosmin versus thallium-201 in coronary artery disease. Am J Cardiol 1993;72:1015-9.