Predominance of Ehrlichia ewingii in Missouri dogs

Journal of Clinical Microbiology

Volumn 41, Issue 10, 2003, Pages 4617-4622

  Liddell, Allison M ^a,e   Stockham, Steven L ^a,f   Scott, Michael A ^c,g   Sumner, John W ^d   Paddock, Christopher D ^d   Gaudreault Keener, Monique ^b   Arens, Max Q ^a,b   Storch, Gregory A ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST LOUIS CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^e InfectiousCare   (United States)

^f KANSAS STATE UNIVERSITY   (United States)

^g Center for Comparative Medicine and Translational Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; CHLORAMPHENICOL; DNA 16S; DOXYCYCLINE;

ANAPLASMA; ANAPLASMA PHAGOCYTOPHILUM; ARTICLE; BACTERIAL GENE; BLOOD; CONTROLLED STUDY; DOG; EHRLICHIA; EHRLICHIA EWINGII; EHRLICHIOSIS; FEMALE; IMMUNOASSAY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCREENING TEST; SPECIES; SYMPTOM; UNITED STATES;

ANIMALS; ANTIBODIES, BACTERIAL; DOG DISEASES; DOGS; EHRLICHIA; EHRLICHIOSIS; MALE; MISSOURI; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY;

ANAPLASMA; ANAPLASMA PHAGOCYTOPHILUM; ANIMALIA; BACTERIA (MICROORGANISMS); CANIS; CANIS FAMILIARIS; EHRLICHIA; EHRLICHIA CANIS; EHRLICHIA CHAFFEENSIS; EHRLICHIA EWINGII;

EID: 0142126406     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.41.10.4617-4622.2003     Document Type: Article

References (33)

1. Anderson, B. E., J. E. Dawson, D. C. Jones, and K. H. Wilson. 1991. Ehrlichia chaffeensis, a new species associated with human ehrlichiosis. J. Clin. Microbiol. 29:2838-2842.
2. Anderson, B. E., J. W. Sumner, J. E. Dawson, T. Tzianabos, C. R. Greene, J. G. Olson, D. B. Fishbein, M. Olsen-Rasmussen, B. P. Holloway, E. H. George, and A. F. Azad. 1992. Detection of the etiologic agent of human ehrlichiosis by polymerase chain reaction. J. Clin. Microbiol. 30:775-780.
3. Arens, M. Q., A. M. Liddell, G. Buening, M. Gaudreault-Keener, J. W. Sumner, J. A. Comer, R. S. Buller, and G. A. Storch. 2003. Detection of Ehrlichia spp. in the blood of wild white-tailed deer in Missouri by PCR assay and serologic analysis. J. Clin. Microbiol. 41:1263-1265.
4. Bakken, J. S., J. S. Dumler, S. M. Chen, M. R. Eckman, L. L. Van Etta, and D. H. Walker. 1994. Hum. granulocytic ehrlichiosis in the upper Midwest United States: a new species emerging? JAMA 272:212-218.
5. Belongia, E. A., K. D. Reed, P. D. Mitchell, C. P. Kolbert, D. H. Persing, J. S. Gill, and J. J. Kazmierczak. 1997. Prevalence of granulocytic Ehrlichia infection among white-tailed deer in Wisconsin. J. Clin. Microbiol. 35:1465-1468.
6. Breitschwerdt, E. B., B. C. Hegarty, and S. I. Hancock. 1998. Sequential evaluation of dogs naturally infected with Ehrlichia canis, Ehrlichia chaffeensis, Ehrlichia equi, Ehrlichia ewingii, or Bartonella vinsonii. J. Clin. Microbiol. 36:2645-2651.
7. Buller, R. S., M. Arens, S. P. Hmiel, C. D. Paddock, J. W. Sumner, Y. Rikhisa, A. Unver, M. Gaudreault-Keener, F. A. Manian, A. M. Liddell, N. Schmulewitz, and G. A. Storch. 1999. Ehrlichia ewingii, a newly recognized agent of human ehrlichiosis. N. Engl. J. Med. 341:148-155.
8. Chen, S. M., J. S. Dumler, J. S. Bakken, and D. H. Walker. 1994. Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease. J. Clin. Microbiol. 32:589-595.
9. Comer, J. A., W. L. Nicholson, C. D. Paddock, J. W. Sumner, and J. E. Childs. 2000. Detection of antibodies reactive with Ehrlichia chaffeensis in the raccoon. J. Wildl. Dis. 36:705-712.
10. Davidson, W. R., J. M. Lockhart, D. E. Stallknecht, E. W. Howerth, J. E. Dawson, and Y. Rechav. 2001. Persistent Ehrlichia chaffeensis infection in white-tailed deer. J. Wildl. Dis. 37:538-546,
11. Dawson, J. E., K. L. Biggie, C. K. Warner, K. Cookson, S. Jenkins, J. F. Levine, and J. G. Olson. 1996. Polymerase chain reaction evidence of Ehrlichia chaffeensis, an etiologic agent of human ehrlichiosis, in dogs from southeast Virginia. Am. J. Vet. Res. 57:1175-1179.
12. Dawson, J. E., and S. A. Ewing. 1992. Susceptibility of dogs to infection with Ehrlichia chaffeensis, causative agent of human ehrlichiosis. Am. J. Vet. Res. 53:1322-1327.
13. Dugan, V. G., S. E. Little, D. E. Stallknecht, and A. D. Beall. 2000. Natural infection of domestic goats with Ehrlichia chaffeensis. J. Clin. Microbiol. 38:448-449.
14. Dumler, J. S., A. F. Barbet, C. P. Bekker, G. A. Dasch, G. H. Palmer, S. C. Ray, Y. Rikihisa, and F. R. Rurangirwa. 2001. Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and "HGE agent" as subjective synonyms of Ehrlichia phagocytophila. Int. J. Syst. Evol. Microbiol. 51:2145-2165.
15. Ewing, S. A., W. R. Roberson, R. G. Buckner, and C. S. Hayat. 1971. A new strain of Ehrlichia canis. J. Am. Vet. Med. Assoc. 159:1771-1774.
16. Goldman, E. E., E. B. Breitschwerdt, C. B. Grindem, B. C. Hegarty, J. J. Walls, and J. S. Dumler. 1998. Granulocytic ehrlichiosis in dogs from North Carolina and Virginia. J. Vet. Intern. Med. 12:61-70.
17. Goodman, J. L., C. Nelson, B. Vitale, J. E. Madigan, J. S. Dumler, T. J. Kurtti, and U. G. Munderloh. 1996. Direct cultivation of the causative agent of human granulocytic ehrlichiosis. N. Engl. J. Med. 334:209-215.
18. Goodman, R. A., E. C. Hawkins, N. J. Olby, C. B. Grindem, B. Hegarty, and E. B. Breitschwerdt. 2003. Molecular identification of Ehrlichia ewingii infection in dogs: 15 cases (1997-2001). JAVMA 222:1102-1107.
19. Greig, B., K. M. Asanovich, P. J. Armstrong, and J. S. Dumler. 1996. Geographic, clinical, serologic, and molecular evidence of granulocytic ehrlichiosis, a likely zoonotic disease, in Minnesota and Wisconsin dogs. J. Clin. Microbiol. 34:44-48.
20. Johansson, K. E., B. Pettersson, M. Uhlen, A. Gunnarsson, M. Malmqvist, and E. Olsson. 1995. Identification of the causative agent of granulocytic ehrlichiosis in Swedish dogs and horses by direct solid phase sequencing of PCR products from the 16S rRNA gene. Res. Vet. Sci. 58:109-112.
21. Kocan, A. A., G. C. Levesque, L. C. Whitworth, G. L. Murphy, S. A. Ewing, and R. W. Barker. 2000. Naturally occurring Ehrlichia chaffeensis infection in coyotes from Oklahoma. Emerg. Infect. Dis. 6:477-480.
22. Kordick, S. K., E. B. Breitschwerdt, B. C. Hegarty, K. L. Southwick, C. M. Colitz, S. I. Hancock, J. M. Bradley, R. Rumbough, J. T. McPherson, and J. N. MacCormack. 1999. Coinfection with multiple tick-borne pathogens in a Walker Hound kennel in North Carolina. J. Clin. Microbiol. 37:2631-2638.
23. Massung, R. F., K. Slater, J. H. Owens, W. L. Nicholson, T. N. Mather, V. B. Solberg, and J. G. Olson. 1998. Nested PCR assay for detection of granulocytic ehrlichiae. J. Clin. Microbiol. 36:1090-1095.
24. McQuiston, J. H., C. D. Paddock, R. C. Holman, and J. E. Childs. 1999. The human ehrlichioses in the United States. Emerg. Infect. Dis. 5:635-642.
25. Murphy, G. L., S. A. Ewing, L. C. Whitworth, J. C. Fox, and A. A. Kocan. 1998. A molecular and serologic survey of Ehrlichia canis, E. chaffeensis, and E. ewingii in dogs and ticks from Oklahoma. Vet. Parasitol. 79:325-339.
26. Paddock, C. D., O. Brenner, C. Vaid, D. B. Boyd, J. M. Berg, R. J. Joseph, S. R. Zaki, and J. E. Childs. 2002. Short report: concurrent Rocky Mountain spotted fever in a dog and its owner. Am. J. Trop, Med. Hyg. 66:197-199.
27. Pancholi, P., C. P. Kolbert, P. D. Mitchell, K. D. Reed, Jr., J. S. Dumler, J. S. Bakken, S. R. Telford III, and D. H. Persing. 1995. Ixodes dammini as a potential vector of human granulocytic ehrlichiosis. J. Infect. Dis. 172:1007-1012.
28. Petrovec, M., J. W. Sumner, W. L. Nicholson, J. E. Childs, F. Strle, J. Barlic, S. Lotric-Furlan, and T. Avsic Zupanc. 1999. Identity of ehrlichial DNA sequences derived from Ixodes ricinus ticks with those obtained from patients with human granulocytic ehrlichiosis in Slovenia. J. Clin. Microbiol. 37:209-210.
29. Rikihisa, Y., S. A. Ewing, and J. C. Fox. 1994. Western immunoblot analysis of Ehrlichia chaffeensis, E. canis, or E. ewingii infections in dogs and humans. J. Clin. Microbiol. 32:2107-2112.
30. Stockham, S. L., D. A. Schmidt, K. S. Curtis, B. G. Schauf, J. W. Tyler, and S. T. Simpson. 1992. Evaluation of granulocytic ehrlichiosis in dogs of Missouri, including serologic status to Ehrlichia canis, Ehrlichia equi, and Borrelia burgdorferi. Am. J. Vet. Res. 53:63-68.
31. Telford, S. R., III, J. E. Dawson, P. Katavolos, C. K. Warner, C. P. Kolbert, and D. H. Persing. 1996. Perpetuation of the agent of human granulocytic ehrlichiosis in a deer tick-rodent cycle. Proc. Natl. Acad. Sci. USA 93:6209-6214.
32. van Heerden, J. 1982. A retrospective study on 120 natural cases of canine ehrlichiosis. J. S. Afr. Vet. Assoc. 53:17-22.
33. Warner, C., and J. Dawson. 1996. Genus- and species-level identification of Ehrlichia species by PCR and sequencing, p. 100-105. In D. H. Persing (ed.), PCR protocols for emerging infectious diseases: a supplement to diagnostic molecular microbiology: principles and applications. ASM Press, Washington, D.C.