The Ethics of Placebo-Controlled Trials

Journal of Bone and Mineral Research

Volumn 18, Issue 6, 2003, Pages 1150-1153

  Weijer, Charles ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO;

CLINICAL RESEARCH; CLINICAL TRIAL; CONFERENCE PAPER; DOCTOR PATIENT RELATION; DRUG APPROVAL; DRUG EFFICACY; DRUG INDICATION; DRUG RESEARCH; DRUG SAFETY; DRUG USE; FOOD AND DRUG ADMINISTRATION; HUMAN; INFORMED CONSENT; MEDICAL ETHICS; MORALITY; OSTEOPOROSIS; PRACTICE GUIDELINE; RISK ASSESSMENT; TREATMENT INDICATION;

BIOMEDICAL AND BEHAVIORAL RESEARCH;

CONTROLLED CLINICAL TRIALS; ETHICS, MEDICAL; FINLAND; HUMAN EXPERIMENTATION; HUMAN RIGHTS; HUMANS; PLACEBOS; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 0142091166     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2003.18.6.1150     Document Type: Conference Paper

References (16)

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5. World Medical Association. 2002 Press release: When are placebo controlled trials ethically acceptable? Available online at http://www.wma.net/e/press/01_19.html. Accessed on August 14, 2002.
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11. Weijer C, Glass KC, Shapiro S 2000 Why clinical equipoise, and not the uncertainty principle, is the moral underpinning of the RCT. Br Med J 321:756-757.
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13. Freedman B 1987 Equipoise and the ethics of clinical research. N Engl J Med 317:141-145.
14. Weijer C 1999 Placebo-controlled trials in schizophrenia: Are they ethical? Are they necessary?. Schizophrenia Res 35:211-218.
15. Tramer MR, Reynolds DJM, Moore RA, McQuay HJ 1998 When placebo controlled trials are essential and equivalence trials are inadequate. Br Med J 317:875-880.
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