Different actions of γ-hydroxybutyrate: A critical outlook

Neurological Research

Volumn 25, Issue 7, 2003, Pages 759-763

  Greiner, Christoph ^a   Röhl, Jens Eric ^b   Ali Gorji, ^b   Wassmann, Hansdetlef ^a   Speckmann, Erwin Josef ^b  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

GABA; Gamma hydroxybutyrate; Hippocampal slice; Ischemia; Neuroprotection

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID DERIVATIVE; 4 HYDROXYBUTYRIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HUMAN; NEUROPROTECTION; NONHUMAN; PATHOPHYSIOLOGY; SEDATION;

ANIMALS; BRAIN; HUMANS; HYPNOTICS AND SEDATIVES; SLEEP; SODIUM OXYBATE;

EID: 0142089943     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164103101202138     Document Type: Article

References (62)

1. Bessmann SP, Fishbein WN. Gamma-hydroxybutyrate, a normal brain metabolite. Nature 1963; 200: 1207-1208
2. Fishbein WN, Bessmann SP. γ-Hydroxybutyrate in mammalian brain. J Biol Chem 1961; 239: 357-361
3. Roth RH. Formation and regional distribution of γ-hydroxybutyric acid in mammalian brain. Biochem Pharmacol 1970; 19: 3013-3019
4. Roth RH, Giarman NJ. Natural occurrence of gamma-hydroxybutyrate in mammalian brain. Biochem Pharmacol 1970; 19: 1087-1093
5. Henderson RS, Holmes CM. Reversal of the anaesthetic action of sodium gamma-hydroxybutyrate. Anaesth Intensive Care 1976; 4: 351-354
6. Howard SG, Feigenbaum JJ. Effects of γ-hydroxybutyrate on central dopamine release in vivo. Biochem Pharmacol 1996; 53:103-110
7. Laborit H. Sodium-4-hydroxybutyrate. Int J Neuropharmacol 1964; 3: 433-452
8. Vickers MD. Gamma hydroxybutyric acid. Clinical pharmacology and current status. Proc R Soc Med 1968; 61: 821-824
9. Centers for Disease Control. Gamma hydroxybutyrate use in New York and Texas, 1995-1996. J Am Med Assoc 1997; 277: 1511
10. Centers for Disease Control. Multistate outbreak of poisonings associated with the illicit use of gamma hydroxybutyrate. J Am Med Assoc 1991; 265: 447-448
11. Stell JM, Ryan JM. Ecstasy and neurodegeneration. Gamma-hydroxybutyrate is a new recreational drug that may lead to loss of consciousness. BMJ 1996; 312: 1493-1494
12. Kuschinsky W, Suda S, Sokoloff L. Influence of gamma-hydroxybutyrate on the relationship between local cerebral glucose utilization and local cerebral blood flow in the rat brain. J Cereb Blood Flow Metab 1985; 5: 58-64
13. Rumigny JF, Cash C, Mandel P, Vincendon G, Maitre M. Evidence that specific succinic semialdehyde reductase is responsible for γ -hydioxybutyrate synthesis in brain tissue slices. FEBS Lett 1981; 134: 96-98
14. B receptors. Eur J Pharmacol 1992; 212: 291-294
15. Snead OC III. The gamma-hydroxybutyrate model of absence seizures: Correlation of regional brain levels of gamma-hydroxybutyric acid and gamma-butyrolactone with spike wave discharges. Neuropharmacology 1991; 30: 161-167
16. Vayer P, Mandel P, Maitre M. Gamma-hydroxybutyrate, a possible neurotransmitter. Life Sci 1987; 41: 1547-1557
17. Maitre M. The gamma-hydroxybutyrate signaling system in brain: Organization and functional implications. Prog Neurobiol 1997; 51: 337-361
18. Snead OC III, Nichols AC. Gamma-hydroxybutyric acid binding sites: Evidence for coupling to a chloride anion channel. Neuropharmacology 1987; 26: 1519-1523
19. Kemmel V, Taleb O, Perard A, Andriamampandry C, Siffert JC, Mark J, Maitre M. Neurochemical and electrophysiological evidence for the existence of a functional gamma-hydroxybutyrate system in NBC-20 neurons. Neuroscience 1998; 86: 989-1000
20. Ratomponirina C, Hodé Y, Hechler V, Maitre M. Gamma-hydroxybutyrate receptor binding in rat brain is inhibited by guanyl nucleotides and pertussis toxin. Neurosci Lett 1995; 189: 51-53
21. Snead OC III, Morley BJ. Ontogeny of gamma-hydroxybutyric acid. I. Regional concentration in developing rat, monkey and human brain. Brain Res 1981; 227: 578-589
22. Chin MY, Kreutzer RA, Dyer JE. Acute poisoning from gamma-hydroxybutyrate in California. West J Med 1992; 156: 380-384
23. Vayer P, Gobaille S, Mandel P, Maitre M. 3′-5′ cyclic-guanosine monophosphate increase in rat brain hippocampus after gamma-hydroxybutyrate administration. Prevention by valproate and naloxone. Life Sci 1987; 41: 605-610
24. Vayer P, Maitre M. Gamma-hydroxybutyrate stimulation of the formation of cyclic GMP and inositol phosphates in rat hippocampal slices. j Neurochem 1989; 52: 1382-1387
25. Madden TE, Johnson SW. Gamma-hydroxybutyrate is a GABAB receptor agonist that increases a potassium conductance in rat ventral tegmental dopamine neurons. J Pharmacol Exp Ther 1998; 287: 261-265
26. Anden NE, Stock G. Inhibitory effect of gammahydroxybutyric acid and gammaaminobutyric acid on the dopamine cells in the substantia nigra. Naunyn Schmiedebergs Arch Pharmacol 1973; 279: 89-92
27. Nissbrandt H, Elverfors A, Engberg G. Pharmacologically induced cessation of burst activity in nigral dopamine neurons: Significance for the terminal dopamine efflux. Synapse 1994; 17: 217-224
28. Roth RH, Doherty JD, Walters JR. Gamma-hydroxybutyrate: A role in the regulation of central dopaminergic neurons. Brain Res 1980; 189: 556-560
29. Hechler V, Peter P, Gobaille S, Bourguignon JJ, Schmitt M, Ehrhardt JD, Mark J, Maitre M. Gamma-hydroxybutyrate ligands possess antidopaminergic and neuroleptic-like activities. J Pharmaco Exp Ther 1993; 264: 1406-1414
30. Dyck LE, Kazakoff CW. Acceleration of the biosynthesis of rat striatal dopamine by incubation and by administration of gamma-butyrolactone. J Neurosci Res 1982; 8: 57-65
31. Handforth A, Sourkes TL. Inhibition by dopamine agonists of dopamine accumulation following gamma-hydroxybutyrate treatment. Eur J Pharmacol 1975; 34: 311-319
32. Miguez I, Aldegunde M, Duran R, Veira JA. Effect of low doses of gamma-hydroxybutyric acid on serotonin, noradrenaline, and dopamine concentrations in rat brain areas. Neurochem Res 1988; 13: 531-533
33. Gobaille S, Schleef C, Hechler V, Viry S, Aunis D, Maitre M. Gamma-hydroxybutyrate increases tryptophan availability and potentiates serotonin turnover in rat brain. Life Sci 2002; 70: 2101-2112
34. Hechler V, Gobaille S, Bourguignon JJ, Maitre M. Extracellular events induced by gamma-hydroxybutyrate in striatum: A microdialysis study. J Neurochem 1991; 56: 938-944
35. Feigenbaum JJ, Simantov R. Lack of effect of gamma-hydroxybutyrate on mu, delta and kappa opioid receptor binding. Neurosci Lett 1996; 212: 5-8
36. Takahara J, Yunoki S, Yakushiji W, Yamauchi J, Yamane Y. Stimulatory effects of gamma-hydroxybutyric acid on growth hormone and prolactin release in humans. J Clin Endocrinol Metab 1977; 44: 1014-1017
37. Ferrara SD, Zotti S, Tedeschi L, Frison G, Castagna F, Gallimberti L, Gessa GL, Palatini P. Pharmacokinetics of gamma-hydroxybutyric acid in alcohol dependent patients after single and repeated oral doses. Br J Clin Pharmacol 1992; 34: 231-235
38. Vree TB, Damsma J, van der Borgert AG, van der Kleijn E. Pharmacokinetics of 4-hydroxybutyric acid in man, rhesus monkey and dogs. In: Frey R, ed. Neue Untersuchungen mit Gamma-Hydroxy-Buttersäure Anaesthesiologie und Intensivmedizin, Berlin: Springer Verlag, 1978: pp. 21-28
39. Kleinschmidt !S, Mertzlufft F. Gamma-hydroxybutyric acid significance for anesthesia and intensive care medicine? Anasthesiol Intensivmed Notfallmed Schmerzther 1995; 30: 393-402
40. Pichlmeier R, Schneck H. Gamma-Hydroxybuttersäure (GHB) als Basis-Sedativum in der Intensivmedizin. Intensiv Notfallbehandl 1991; 16: 106-112
41. Plangger C. Effect of gammahydroxybutyrate on intracranial pressure, mean systemic arterial pressure and cerebral perfusion pressure in experimentally induced brain oedema of the rat. Zentralbl Neurochir 1990; 51: 24-33
42. Mamelak M. Gammahydroxybutyrate: An endogenous regulator of energy metabolism. Neurosci Biobehav Rev 1989; 13: 187-198
43. Haller C, Mende M, Schuler F, Schuh R, Schrock H, Kuschinsky W. Effect of gamma-hydroxybutyrate on local and global glucose metabolism in the anesthetized cat brain. J Cereb Blood Flow Metab 1990; 10: 493-498
44. Strong AJ. Gamma-hydroxybutyric acid and intracranial pressure. Lancet 1984; 1: 1304
45. Balestrino M. Pathophysiology of anoxic depolarization: New findings and a working hypothesis. J Neurosci Methods 1995; 59: 99-103
46. Caspers H, Speckmann EJ. Cortical DC-shifts associated with changes of gas tension in blood and tissue. In: Remond A, ed. Handbook of Electroencephalography and Clinical Neurophysiology, Amsterdam: Elsevier, 1974: pp. 41-65
47. +. Presse Méd 1960; 50: 1867-1869
48. Cash CD, Gobaille S, Kemmel V, Andriamampandry C, Maitre M. Gamma-hydroxybutyrate receptor function studied by the modulation of nitric oxide synthase activity in rat frontal cortex punches. Niochem Pharmacol 1999; 58: 1815-1819
49. Jensen K, Mody I. GHB depresses fast excitatory and inhibitory synaptic transmission via GABAB receptors in mouse neocortical neurons. Cerebral Cortex 2001; 11: 424-429
50. Roquefeuil B, Escuret E, Duboin MP, Baidy-Moulinier M. The effect of gamma-OH on cerebral metabolism and blood flow in human patients. Rev Electroencephalogr Neurophysiol Clin 1977; 7: 93-97
51. Snead OC III. Gamma-hydroxybutyrate model of generalized absence seizures: Further characterization and comparison with other absence models. Epilepsia 1988; 29: 361-368
52. Maitre M, Hechler V, Vayer P, Gobaille S, Cash CD, Schmitt M, Bourguignon JJ. A specific gamma-hydroxybutyrate receptor ligand possesses both antagonistic and anticonvulsant properties. J Pharmacol Exp Ther 1990; 255: 657-663
53. Entholzner E, Mielke L, Pichimeier R, Weber F, Schneck H. EEG changes during sedation with gamma-hydroxybutyric acid. Anaesthesist 1995; 44: 345-350
54. Hunter AS, Long WJ, Ryrie CG. An evaluation of gamma-hydroxybutyric acid in paediatric practice. Br J Anaesth 1971; 43: 620-628
55. Hoes MJ, Vree TB, Gueleu PJ. Gamma-hydroxybutyric acid as hypnotic. Clinical and pharmacokinetic evaluation of gamma-hydroxybutiric acid as hypnotic in man. Encephale 1980; 6: 93-99
56. Okun MS, Boothby LA, Bartfield RB, Doering PL. GHB: An important pharmacologic and clinical update. J Pharm Pharm Sci 2001; 4: 165-175
57. Mitler MM, Hajdukovic R. Relative efficacy of drugs for the treatment of sleepiness in narcolepsy. Sleep 1991; 14: 218-220
58. Schmidt C, Gobaille S, Hechler V, Schmitt M, Bourguignon JJ, Maitre M. Anti-sedative and anti-cataleptic properties of NCS-382, a gamma-hydroxybutyrate receptor antagonist. Eur J Pharmacol 1991; 203: 393-397
59. Kam PC, Yoong FF. Gamma-hydroxybutyric acid: An emerging recreational drug. Anaesthesia 1998; 53: 1195-1198
60. Galloway GP, Frederick SL, Staggers FE Jr, Gonzales M, Stalcup SA, Smith DE. Gamma-hydroxybutyrate: An emerging drug of abuse that causes physical dependence. Addiction 1997; 92: 89-96
61. Gallimberti L, Cibin M, Pagnin P, Sabbion R, Pani PP, Pirastu R, Ferrara SD, Gessa GL. Gamma-hydroxybutyric acid for treatment of opiate withdrawal syndrome. Neuropsychopharmacology 1993; 9: 77-81
62. Ueki Y. Effects of gamma-dehydroxybutyrate on monoamine metabolism and protein synthesis after transient global cerebral ischemia. No Shinkei Geka 1992; 20: 937-946