메뉴 건너뛰기




Volumn 149, Issue 3, 2003, Pages 506-512

A multiparameter flow cytometric analysis of the effect of bexarotene on the epidermis of the psoriatic lesion

Author keywords

Bexarotene; Cell proliferation; Keratinization; Psoriasis; Retinoid X receptor

Indexed keywords

BEXAROTENE; KERATIN; KERATIN 10; KERATIN 6; RETINOID X RECEPTOR; THERMOLYSIN; UNCLASSIFIED DRUG; VIMENTIN;

EID: 0142088943     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.2003.05474.x     Document Type: Article
Times cited : (7)

References (28)
  • 1
    • 0031763757 scopus 로고    scopus 로고
    • Rational design of receptor-selective retinoids
    • Chandraratna RA. Rational design of receptor-selective retinoids. J Am Acad Dermatol 1998; 39: S124-8.
    • (1998) J Am Acad Dermatol , vol.39
    • Chandraratna, R.A.1
  • 2
    • 0030887795 scopus 로고    scopus 로고
    • Current use and future potential role of retinoids in dermatology
    • Orfanos CE, Zouboulis CC, Almond-Roesler B et al. Current use and future potential role of retinoids in dermatology. Drugs 1997; 53: 358-88.
    • (1997) Drugs , vol.53 , pp. 358-388
    • Orfanos, C.E.1    Zouboulis, C.C.2    Almond-Roesler, B.3
  • 3
    • 0030112308 scopus 로고    scopus 로고
    • Vitamin D-retinoid association: Molecular basis and clinical applications
    • Carlberg C, Saurat JH. Vitamin D-retinoid association: molecular basis and clinical applications. J Invest Dermatol Symp Proc 1996; 1: 82-6.
    • (1996) J Invest Dermatol Symp Proc , vol.1 , pp. 82-86
    • Carlberg, C.1    Saurat, J.H.2
  • 4
    • 0031024325 scopus 로고    scopus 로고
    • Initial clinical trial of a selective retinoid X receptor ligand, LGD1069
    • Miller VA, Benedetti FM, Rigas JR et al. Initial clinical trial of a selective retinoid X receptor ligand, LGD1069. J Clin Oncol 1997; 15: 790-5.
    • (1997) J Clin Oncol , vol.15 , pp. 790-795
    • Miller, V.A.1    Benedetti, F.M.2    Rigas, J.R.3
  • 5
    • 0032790681 scopus 로고    scopus 로고
    • A phase I study of LGD1069 in adults with advanced cancer
    • Rizvi NA, Marshall JL, Dahut W et al. A phase I study of LGD1069 in adults with advanced cancer. Clin Cancer Res 1999; 5: 1658-64.
    • (1999) Clin Cancer Res , vol.5 , pp. 1658-1664
    • Rizvi, N.A.1    Marshall, J.L.2    Dahut, W.3
  • 6
    • 0034219447 scopus 로고    scopus 로고
    • A phase II evaluation of bexarotene (Targretin) capsules in patients with metastatic melanoma
    • Bedikian AY, Plager C, Papadopoulos N et al. A phase II evaluation of bexarotene (Targretin) capsules in patients with metastatic melanoma. Oncol Rep 2000; 7: 883-6.
    • (2000) Oncol Rep , vol.7 , pp. 883-886
    • Bedikian, A.Y.1    Plager, C.2    Papadopoulos, N.3
  • 7
    • 0032006028 scopus 로고    scopus 로고
    • Beyond tamoxifen: The retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma
    • Bischoff ED, Gottardis MM, Moon TE et al. Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma. Cancer Res 1998; 58: 479-84.
    • (1998) Cancer Res , vol.58 , pp. 479-484
    • Bischoff, E.D.1    Gottardis, M.M.2    Moon, T.E.3
  • 8
    • 0142112710 scopus 로고    scopus 로고
    • Systemic bexarotene (Targretin, Ligand Pharmaceuticals Inc.) significantly inhibits proliferation and inflammation and improves normal differentiation in moderate to severe plaque psoriasis: An immunohistochemical study
    • Smit JV, de Jong EM, van Hooijdonk CA, van de Kerkhof PC. Systemic bexarotene (Targretin, Ligand Pharmaceuticals Inc.) significantly inhibits proliferation and inflammation and improves normal differentiation in moderate to severe plaque psoriasis: an immunohistochemical study. Br J Dermatol 1999; 141: 992-3.
    • (1999) Br J Dermatol , vol.141 , pp. 992-993
    • Smit, J.V.1    De Jong, E.M.2    Van Hooijdonk, C.A.3    Van De Kerkhof, P.C.4
  • 9
    • 0001181426 scopus 로고    scopus 로고
    • A multicentre phase 2 clinical and immunohistochemical trial of systemic bexarotene (Targretin) in psoriasis
    • Abstr.
    • Smit JV, de Jong EM, van Hooijdonk CA et al. A multicentre phase 2 clinical and immunohistochemical trial of systemic bexarotene (Targretin) in psoriasis. J Invest Dermatol 2000; 114: 776 (Abstr.).
    • (2000) J Invest Dermatol , vol.114 , pp. 776
    • Smit, J.V.1    De Jong, E.M.2    Van Hooijdonk, C.A.3
  • 10
    • 0024368644 scopus 로고
    • Flow cytometric analysis of epidermal subpopulations from normal and psoriatic skin using monoclonal antibodies against intermediate filaments
    • van Erp PE, Rijzewijk JJ, Boezeman JB et al. Flow cytometric analysis of epidermal subpopulations from normal and psoriatic skin using monoclonal antibodies against intermediate filaments, Am J Pathol 1989; 135: 865-70.
    • (1989) Am J Pathol , vol.135 , pp. 865-870
    • Van Erp, P.E.1    Rijzewijk, J.J.2    Boezeman, J.B.3
  • 11
    • 0030863045 scopus 로고    scopus 로고
    • Multiparameter flow cytometry as a tool to evaluate antipsoriatic therapy
    • Glade CP, van Erp PE, Boezeman JB et al. Multiparameter flow cytometry as a tool to evaluate antipsoriatic therapy. Br J Dermatol 1997; 137: 367-75.
    • (1997) Br J Dermatol , vol.137 , pp. 367-375
    • Glade, C.P.1    Van Erp, P.E.2    Boezeman, J.B.3
  • 12
    • 0034652621 scopus 로고    scopus 로고
    • Novel functional multiparameter flow cytometric assay to characterize proliferation in skin
    • Mortimers JM, Goossen JW, van de Kerkhof PC et al. Novel functional multiparameter flow cytometric assay to characterize proliferation in skin. Cytometry 2000; 42: 43-9.
    • (2000) Cytometry , vol.42 , pp. 43-49
    • Mortimers, J.M.1    Goossen, J.W.2    Van De Kerkhof, P.C.3
  • 13
    • 0029990997 scopus 로고    scopus 로고
    • Multiparameter flow cytometric characterization of epidermal cell suspensions prepared from normal and hyperproliferative human skin using an optimized thermolysin-trypsin protocol
    • Glade CP, Seegers BA, Meulen EF et al. Multiparameter flow cytometric characterization of epidermal cell suspensions prepared from normal and hyperproliferative human skin using an optimized thermolysin-trypsin protocol. Arch Dermatol Res 1996; 288: 203-10.
    • (1996) Arch Dermatol Res , vol.288 , pp. 203-210
    • Glade, C.P.1    Seegers, B.A.2    Meulen, E.F.3
  • 14
    • 0028801397 scopus 로고
    • Topical treatment of psoriatic plaques with 1 alpha, 24 dihydroxyvitamin D3: A multiparameter flow cytometrical analysis of epidermal growth, differentiation and inflammation
    • Glade CP, van Erp PE, van Hooijdonk CA et al. Topical treatment of psoriatic plaques with 1 alpha, 24 dihydroxyvitamin D3: a multiparameter flow cytometrical analysis of epidermal growth, differentiation and inflammation. Acta Derm Venereol 1995; 75: 381-5.
    • (1995) Acta Derm Venereol , vol.75 , pp. 381-385
    • Glade, C.P.1    Van Erp, P.E.2    Van Hooijdonk, C.A.3
  • 15
    • 0029840873 scopus 로고    scopus 로고
    • Epidermal cell DNa content and intermediate filaments keratin 10 and vimentin after treatment of psoriasis with calcipotriol cream once daily, twice daily and in combination with clobetasone 17-butyrate cream or betamethasone 17-valerate cream: A comparative flow cytometric study
    • Glade CP, van Erp PE, van de Kerkhof PC. Epidermal cell DNA content and intermediate filaments keratin 10 and vimentin after treatment of psoriasis with calcipotriol cream once daily, twice daily and in combination with clobetasone 17-butyrate cream or betamethasone 17-valerate cream: a comparative flow cytometric study. Br J Dermatol 1996; 135: 379-84.
    • (1996) Br J Dermatol , vol.135 , pp. 379-384
    • Glade, C.P.1    Van Erp, P.E.2    Van De Kerkhof, P.C.3
  • 16
    • 0031947674 scopus 로고    scopus 로고
    • A clinical and flow cytometric model to study remission and relapse in psoriasis
    • Glade CP, van Erp PE, Werner-Schlenzka H et al. A clinical and flow cytometric model to study remission and relapse in psoriasis. Acta Derm Venereol 1998; 78: 180-5.
    • (1998) Acta Derm Venereol , vol.78 , pp. 180-185
    • Glade, C.P.1    Van Erp, P.E.2    Werner-Schlenzka, H.3
  • 17
    • 0033430998 scopus 로고    scopus 로고
    • Clobetasol under hydrocolloid occlusion in psoriasis results in a complete block of proliferation and in a rebound of lesions following discontinuation
    • Mommers JM, van Erp PE, van de Kerkhof PC. Clobetasol under hydrocolloid occlusion in psoriasis results in a complete block of proliferation and in a rebound of lesions following discontinuation. Dermatology 1999; 199: 323-7.
    • (1999) Dermatology , vol.199 , pp. 323-327
    • Mommers, J.M.1    Van Erp, P.E.2    Van De Kerkhof, P.C.3
  • 18
    • 0033818066 scopus 로고    scopus 로고
    • Changes in keratin 6 and keratin 10 (co-) expression in lesional and symptomless skin of spreading psoriasis
    • Mommers JM, van Rossum MM, van Erp PE et al. Changes in keratin 6 and keratin 10 (co-) expression in lesional and symptomless skin of spreading psoriasis. Dermatology 2000; 201: 15-20.
    • (2000) Dermatology , vol.201 , pp. 15-20
    • Mommers, J.M.1    Van Rossum, M.M.2    Van Erp, P.E.3
  • 19
    • 0142049337 scopus 로고    scopus 로고
    • Monitoring psoriasis: An improved flow cytometric assay
    • Abstr.
    • Franssen ME, Mommers JM, Cloin WA et al. Monitoring psoriasis: an improved flow cytometric assay. J Invest Dermatol 2000; 115: 582 (Abstr.).
    • (2000) J Invest Dermatol , vol.115 , pp. 582
    • Franssen, M.E.1    Mommers, J.M.2    Cloin, W.A.3
  • 20
    • 0018099294 scopus 로고
    • Severe psoriasis - Oral therapy with a new retinoid
    • Fredriksson T, Pettersson U. Severe psoriasis - oral therapy with a new retinoid. Dermatologica 1978; 157: 238-44.
    • (1978) Dermatologica , vol.157 , pp. 238-244
    • Fredriksson, T.1    Pettersson, U.2
  • 21
    • 0001944768 scopus 로고
    • Flow cytometric methods in human skin with respect to cell cycle kinetics
    • (Camplejohn RS, Wright N, eds). Edinburgh: Churchill Livingstone
    • Bauer FW, Boezeman JB. Flow cytometric methods in human skin with respect to cell cycle kinetics. In: Psoriasis: Cell Proliferation (Camplejohn RS, Wright N, eds). Edinburgh: Churchill Livingstone, 1983; 104-16.
    • (1983) Psoriasis: Cell Proliferation , pp. 104-116
    • Bauer, F.W.1    Boezeman, J.B.2
  • 22
    • 0034326254 scopus 로고    scopus 로고
    • Induction of adipocyte-specific gene expression is correlated with mammary tumor regression by the retinoid X receptor-ligand LGD1069 (targretin)
    • Agarwal VR, Bischoff ED, Hermann T et al. Induction of adipocyte-specific gene expression is correlated with mammary tumor regression by the retinoid X receptor-ligand LGD1069 (targretin). Cancer Res 2000; 60: 6033-8.
    • (2000) Cancer Res , vol.60 , pp. 6033-6038
    • Agarwal, V.R.1    Bischoff, E.D.2    Hermann, T.3
  • 23
    • 0033780102 scopus 로고    scopus 로고
    • Efficacy of LGD1069 (Targretin), a retinoid X receptor-selective ligand, for treatment of uterine leiomyoma
    • Gamage SD, Bischoff ED, Burroughs KD et al. Efficacy of LGD1069 (Targretin), a retinoid X receptor-selective ligand, for treatment of uterine leiomyoma. J Pharmacol Exp Ther 2000; 295: 677-81.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 677-681
    • Gamage, S.D.1    Bischoff, E.D.2    Burroughs, K.D.3
  • 24
    • 0033978157 scopus 로고    scopus 로고
    • Receptor mechanisms mediating differentiation and proliferation effects of retinoids on neuroblastoma cells
    • Hewson QC, Lova PE, Malcolm AJ et al. Receptor mechanisms mediating differentiation and proliferation effects of retinoids on neuroblastoma cells. Neurosci Lett 2000; 279: 113-16.
    • (2000) Neurosci Lett , vol.279 , pp. 113-116
    • Hewson, Q.C.1    Lova, P.E.2    Malcolm, A.J.3
  • 25
    • 0028022017 scopus 로고
    • Retinoid-resistant estrogen receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-alpha acquire sensitivity to growth inhibition by retinoids
    • Sheikh MS, Shao ZM, Li XS et al. Retinoid-resistant estrogen receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-alpha acquire sensitivity to growth inhibition by retinoids. J Biol Chem 1994; 269: 21440-7.
    • (1994) J Biol Chem , vol.269 , pp. 21440-21447
    • Sheikh, M.S.1    Shao, Z.M.2    Li, X.S.3
  • 26
    • 0029731340 scopus 로고    scopus 로고
    • Chemoprevention of mammary carcinoma by LGD1069 (Targretin): An RXR-selective ligand
    • Gottardis MM, Bischoff ED, Shirley MA et al. Chemoprevention of mammary carcinoma by LGD1069 (Targretin): an RXR-selective ligand. Cancer Res 1996; 56: 5566-70.
    • (1996) Cancer Res , vol.56 , pp. 5566-5570
    • Gottardis, M.M.1    Bischoff, E.D.2    Shirley, M.A.3
  • 27
    • 0028958047 scopus 로고
    • Effects of topical treatment with budesonide on parameters for epidermal proliferation, keratinization and inflammation in psoriasis
    • de Jong EM, Ferrier CM, de Zwart A et al. Effects of topical treatment with budesonide on parameters for epidermal proliferation, keratinization and inflammation in psoriasis. J Dermatol Sci 1995; 9: 185-94.
    • (1995) J Dermatol Sci , vol.9 , pp. 185-194
    • De Jong, E.M.1    Ferrier, C.M.2    De Zwart, A.3
  • 28
    • 0025194468 scopus 로고
    • DNA content and Ks8 12 binding of the psoriatic lesion during treatment with the vitamin D3 analogue MC903 and betamethasone
    • de Mare S, de Jong EG, van de Kerkhof PC. DNA content and Ks8 12 binding of the psoriatic lesion during treatment with the vitamin D3 analogue MC903 and betamethasone. Br J Dermatol 1990; 123: 291-5.
    • (1990) Br J Dermatol , vol.123 , pp. 291-295
    • De Mare, S.1    De Jong, E.G.2    Van De Kerkhof, P.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.