High-Level Expression of Full-Length Antibodies Using Trans-Complementing Expression Vectors

Biotechnology and Bioengineering

Volumn 84, Issue 4, 2003, Pages 439-444

  Bianchi, Allison A ^a   McGrew, Jeffrey T ^a  

^a AMGEN INC   (United States)

Author keywords

Antibody production; Bicistronic vectors; Cell line; Dihydrofolate reductase; Recombinant antibodies

Indexed keywords

CELLS; CLONING; DISEASES;

CELL LINES;

ANTIBODIES;

ANTIBODY; DIHYDROFOLATE REDUCTASE; LEUCINE ZIPPER PROTEIN; METHOTREXATE; RECOMBINANT ANTIBODY;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; BICISTRONIC VECTOR; CELL CLONE; CELL LINE; CELL SURVIVAL; CONTROLLED STUDY; CULTURE MEDIUM; EXPRESSION VECTOR; MAMMAL CELL; NONHUMAN; PROTEIN EXPRESSION;

ANIMALS; ANTIBODIES; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; CRICETULUS; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; IMMUNOGLOBULIN G; METHOTREXATE; MICE; RECOMBINANT PROTEINS; TRANSFECTION;

MAMMALIA; VECTORS;

EID: 0142073269     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10790     Document Type: Article

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