Effects of ploidy, growth conditions and the mitochondrial nucleoid-associated protein llv5p on the rate of mutation of mitochondrial DNA in Saccharomyces cerevisiae

Current Genetics

Volumn 44, Issue 1, 2003, Pages 26-37

  Sia, Rey A L ^b   Urbonas, Beth L ^c   Sia, Elaine Ayres ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

DNA repair; General amino acid control; Microsatellites; Yeast

Indexed keywords

MICROSATELLITE DNA; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; NUCLEOID ASSOCIATED PROTEIN ILV5P; NUCLEOPROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BUD; CELL GROWTH; CONTROLLED STUDY; CULTURE MEDIUM; DIPLOIDY; DNA CONTENT; DNA STRUCTURE; EUKARYOTE; FRAMESHIFT MUTATION; FUNGAL CELL; FUNGUS GROWTH; GENE EXPRESSION; GENE MUTATION; GENE SEGREGATION; HAPLOIDY; MATING TYPE; MOLECULAR SIZE; MOLECULAR STABILITY; MUTATION RATE; NONHUMAN; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PLOIDY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN MALNUTRITION; SACCHAROMYCES CEREVISIAE;

AMINO ACIDS; CULTURE MEDIA; DNA, MITOCHONDRIAL; GENE EXPRESSION; MICROSATELLITE REPEATS; MITOCHONDRIAL PROTEINS; MUTATION; PLOIDIES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION;

EUKARYOTA; FUNGI; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0142061168     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00294-003-0420-5     Document Type: Article

References (28)

1. Baladron V, Ufano S, Duenas E, Martin-Cuadrado AB, Rey F del, Vazquez de Aldana CR (2002) Eng 1 p, an endo-1,3-β-glucanase localized at the daughter side of the septum, is involved in cell separation in Saccharomyces cerevisiae. Eukaryot Cell 1:774-786
2. Bateman JM, Perlman PS, Butow RA (2002) Mutational bisection of the mitochondrial DNA stability and amino acid biosynthetic functions of Ilv5p of budding yeast. Genetics 161:1043-1052
3. Dujon B (1981) Mitochondrial genetics and functions. In: Strathern JN, Jones EW, Broach JR (eds) Molecular biology of the yeast Saccharomyces: life cycle and inheritance. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., pp 505-635
4. Galitski T, Saldanha AJ, Styles CA, Lander ES, Fink CR (1999) Ploidy regulation of gene expression. Science 285:251-254
5. Grimes GW, Mahler HR, Perlman PS (1974) Nuclear gene dosage effects on mitochondrial mass and DNA. J Cell Biol 61:565-574
6. Herskowitz I, Jensen RE (1991) Putting the HO gene to work: practical uses for mating-type switching. Methods Enzymol 194:132-146
7. Hinnebusch AG (1992) General and pathway-specific regulatory mechanisms controlling the synthesis of amino acid biosynthetic enzymes in Saccharomyces cerevisiae. In: Jones EW, Pringle JR, Broach JR (eds) The molecular and cellular biology of the yeast Saccharomyces. Cold Spring Harbor Press, Plain-view, N.Y., pp 319-414
8. Hoffman DS, Winston F (1987) A ten minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of E. coli. Gene 57:267-272
9. Jiang JC, Jaruga E, Repnevskaya MV, Jazwinski SM (2000) An intervention resembling caloric restriction prologs life span and retards aging in yeast. FASEB J 14:2135-2137
10. Knight SAB, Labbe S, Kwon LF, Kosman DJ, Thiele DJ (1996) A widespread transposable element masks expression of a yeast copper transport gene. Genes Dev 10:1917-1929
11. Lea DE, Coulson CA (1949) The distribution of the number of mutants in bacterial populations. J Genet 49:264-285
12. Lin S-J, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, et al (2002) Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418:344 348
13. MacAlpine DM, Perlman PS, Butow RA (2000) The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway. EMBO J 19:767-775
14. Masoro EJ (1995) Dietary restriction. Exp Gerontol 30:291-298
15. Mortimer RK, Johnston JR (1959) Life span of individual yeast cells. Nature 183:1751-1752
16. Natarajan K, Meyer MR, Jackson BM, Slade D, Roberts C, et al (2001) Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol Cell Biol 21:4347-4368
17. Sarkar PS, Chang H-C, Boudi FB, Reddy S (1998) CTG repeats show bimodal amplification in E. coli. Cell 95:531-540
18. Scheffler I (1999) Mitochondria. Wiley-Liss, New York
19. Sherman F (1991) Getting started with yeast. In: Guthrie C, Fink GR (eds) Guide to yeast genetics and molecular biology. Academic Press, San Diego, Calif., pp 3-37
20. Sia EA, Butler CA, Dominska M, Greenwell P, Fox TD, et al (2000) Analysis of microsatellite mutations in the mitochondrial DNA of Saccharomyces cerevisiae. Proc Natl Acad Sci USA 97:250-255
21. Sikorski RS, Hieter P (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27
22. Spode I, Maiwald D, Hollenberg CP, Suckow M (2002) ATF/ CREB sites present in sub-telomeric regions of Saccharomyces cerevisiae chromosomes are part of promoters and act as UAS/ URS of highly conserved COS genes. J Mol Biol 319:407-420
23. Steele DF, Butler CA, Fox TD (1996) Expression of a recoded nuclear gene inserted into yeast mitochondrial DNA is limited by mRNA-specific translational activation. Proc Natl Acad Sci USA 93:5253-5257
24. Thorsness PE, Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134:21-28
25. Weindruch R, Sohal RS (1997) Caloric intake and aging. N Engl J Med 337:986-994
26. Wierdl M, Greene CN, Datta A, Jinks-Robertson S, Petes TD (1996) Destabilization of simple repetitive DNA sequences by transcription in yeast. Genetics 143:713-721
27. Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H, Chu AM, Connelly C, et al (1999) Functional characterization of the Saccharomyces cerevisiae genome by gene deletion and parallel analysis. Science 285:901-906
28. Zelenaya-Troitskaya O, Perlman PS Butow RA (1995) An enzyme in yeast mitochondria, that catalyzes a step in branched-chain amino acid biosynthesis also functions in mitochondrial DNA stability. EMBO J 14:3268-3276