Quantitative structure-activity relationships for predicting skin and respiratory sensitization

Environmental Toxicology and Chemistry

Volumn 22, Issue 8, 2003, Pages 1855-1861

  Rodford, Rosemary ^a   Patlewicz, Grace ^b   Walker, John D ^c   Payne, Martin P ^d  

^a Solo Star   (United Kingdom)

^b UNILEVER RESEARCH   (United Kingdom)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d HEALTH AND SAFETY LABORATORY   (United Kingdom)

Author keywords

Expert system; Guinea pig maximization; Local lymph node assay; Relative alkylation index; Structure activity relationship

Indexed keywords

DATA REDUCTION; HEALTH HAZARDS; RESPIRATORY SYSTEM; SENSORY PERCEPTION; SKIN;

RESPIRATORY SENSITIZATION;

TOXICITY;

6 AMINOPENICILLANIC ACID; AMINO ACID; AMPICILLIN; CARMINIC ACID; CEFALEXIN; CHLORHEXIDINE; CHLOROTHALONIL; DICHLORVOS; EPIGALLOCATECHIN GALLATE; ETHANOLAMINE; ETHYLENEDIAMINE; FENTHION; ISOCYANIC ACID DERIVATIVE; ISONIAZID; MALEIC ANHYDRIDE; METHYLDOPA; NAPHTHALENE DERIVATIVE; NICKEL SULFATE; PENICILLANIC ACID DERIVATIVE; PENICILLIN G; PHENOL DERIVATIVE; PHTHALIC ANHYDRIDE; PIPERACILLIN; PIPERAZINE; PIPERAZINE DERIVATIVE; PLATINUM DERIVATIVE; TOLUENE DIISOCYANATE; TOSYLCHLORAMIDE SODIUM; TRIMELLITIC ANHYDRIDE; TYLOSIN;

ALKYLATION; ANIMAL MODEL; GUINEA PIG; LYMPH NODE; NONHUMAN; OCCUPATIONAL ALLERGY; OCCUPATIONAL ASTHMA; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT DISEASE; REVIEW; SENSITIZATION; SKIN ALLERGY; SKIN IRRITATION; SOLUBILITY; ANIMAL; BIOASSAY; EXPOSURE; FORECASTING; HUMAN; IMMUNIZATION; IMMUNOLOGY; INTRADERMAL DRUG ADMINISTRATION; PATHOLOGY; POLLUTANT; SKIN TEST; THEORETICAL MODEL;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

ADMINISTRATION, CUTANEOUS; ANIMALS; BIOLOGICAL ASSAY; ENVIRONMENTAL POLLUTANTS; FORECASTING; HUMANS; IMMUNIZATION; INHALATION EXPOSURE; LYMPH NODES; MODELS, THEORETICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SKIN TESTS;

EID: 0142057080     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/01-438     Document Type: Review

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