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1
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0028155686
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Workshop on status of test methods for assessing potential of chemicals to induce respiratory allergic reactions
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Seigrade, M.J.K.1
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Tepper, J.S.6
Henry, M.C.7
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2
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Immunotoxicologic evaluation of the respiratory system: Animal models for immediate-and delayed-onset pulmonary hypersensitivity
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The induction of respiratory allergy in guinea-pigs following intradermal injection of trimellitic anhydride : A comparison with the response to 2,4-dinitrochlorobenzene
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0025996061
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Validation of a non-invasive technique to assess immediate or delayed onset of airway hypersensitivity in guinea pigs
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6
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Specific immunological and bronchopulmonary responses following intradermal sensitization to free trimellitic anhydride in guinea pigs
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[6] Hayes, J.P., Daniel, R., Tee, R.D., Barnes, P.J., Chung, K.F. and Newman Taylor, A.J. (1992) Specific immunological and bronchopulmonary responses following intradermal sensitization to free trimellitic anhydride in guinea pigs. Clin. Exp. Allergy 22, 694-700.
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7
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A tier approach for evaluating the respiratory allergenicity of low molecular weight chemicals
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Sarlo, K.1
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8
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0028278872
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Animal models of occupational asthma
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Eur. Respir. J.
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Karol, M.H.1
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9
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0028348113
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Induction of respiratory hypersensitivity to diphenylmethane-4,4′-diisocyanate (MDI) in guinea pigs. Influence of route of exposure
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[9] Rattray, N.J., Botham, P.A., Hext, P.M., Woodcock, D.R., Fielding, I., Dearman, R.J. and Kimber, I. (1994) Induction of respiratory hypersensitivity to diphenylmethane-4,4′-diisocyanate (MDI) in guinea pigs. Influence of route of exposure. Toxicology 88, 15-30.
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Rattray, N.J.1
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Woodcock, D.R.4
Fielding, I.5
Dearman, R.J.6
Kimber, I.7
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10
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0028022935
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Assessment of respiratory hypersensitivity in guinea-pigs sensitized to diphenylmethane-4,4′-diisocyanate (MDI) and challenged with MDI, acetylcholine or MDI-albumin conjugate
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[10] Pauluhn, J. and Mohr, U. (1994) Assessment of respiratory hypersensitivity in guinea-pigs sensitized to diphenylmethane-4,4′-diisocyanate (MDI) and challenged with MDI, acetylcholine or MDI-albumin conjugate. Toxicology 92, 53-74.
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Toxicology
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Pauluhn, J.1
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11
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0028878776
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A two-centre study for the evaluation and validation of an animal model for the assessment of the potential of small molecular weight chemicals to cause respiratory allergy
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[11] Blaikie, L., Morrow, T., Wilson, A.P., Hext, P., Hartop, P.J., Rattray, N.J., Woodcock, D. and Botham, P.A. (1995) A two-centre study for the evaluation and validation of an animal model for the assessment of the potential of small molecular weight chemicals to cause respiratory allergy. Toxicology 96, 37-50.
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Toxicology
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Blaikie, L.1
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12
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84940627661
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Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody
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[12] Dearman, R.J., Hegarty, J.M. and Kimber, I. (1991) Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody. Int. Arch. Allergy. Appl. Immunol. 95, 70-76.
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Dearman, R.J.1
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13
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0025905268
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Differential stimulation of immune function by respiratory and contact chemical allergens
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[13] Dearman, R.J. and Kimber, I. (1991) Differential stimulation of immune function by respiratory and contact chemical allergens. Immunology 72, 563-570.
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Immunology
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Dearman, R.J.1
Kimber, I.2
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14
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0026505330
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Divergent immune responses to respiratory and contact chemical allergens: Antibody elicited by phthalic anhydride and oxazolone
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[14] Dearman, R.J. and Kimber, I. (1992) Divergent immune responses to respiratory and contact chemical allergens: antibody elicited by phthalic anhydride and oxazolone. Clin. Exp. Allergy 22, 241-250.
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Clin. Exp. Allergy
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Dearman, R.J.1
Kimber, I.2
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15
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0026549196
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Characterization of murine immune responses to allergenic diisocyanates
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[15] Dearman, R.J., Spence, L.M. and Kimber, I. (1992) Characterization of murine immune responses to allergenic diisocyanates. Toxicol. Appl. Pharmacol. 112, 190-197.
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Dearman, R.J.1
Spence, L.M.2
Kimber, I.3
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16
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0026655094
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Differential ability of occupational chemical contact and respiratory allergens to cause immediate and delayed dermal hypersensitivity reactions in mice
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[16] Dearman, R.J., Mitchell, J.A., Basketter, D.A. and Kimber, I. (1992) Differential ability of occupational chemical contact and respiratory allergens to cause immediate and delayed dermal hypersensitivity reactions in mice. Int. Arch. Allergy Immunol. 97, 315-321
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Int. Arch. Allergy Immunol.
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Dearman, R.J.1
Mitchell, J.A.2
Basketter, D.A.3
Kimber, I.4
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17
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0026669562
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The cellular and molecular basis for divergent allergic responses to chemicals
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[17] Dearman, R.J., Basketter, D.A., Coleman, J.W. and Kimber, I. (1992) The cellular and molecular basis for divergent allergic responses to chemicals. Chem. Biol. Interact. 84, 1-10.
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Chem. Biol. Interact.
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Dearman, R.J.1
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18
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0027990848
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Inducible interleukin-4-secreting cells provoked in mice during chemical sensitisation
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[18] Dearman, R.J., Ramdin, L.S.P., Basketter, D.A. and Kimber, I. (1994) Inducible interleukin-4-secreting cells provoked in mice during chemical sensitisation. Immunology 81, 551-557.
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Immunology
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19
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0029620692
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Differential cytokine production following chronic exposure of mice to chemical respiratory and contact allergens
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Immunology
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IL-4 is required to generate and sustain in vivo IgE responses
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IFN-γ regulates the isotypes of Ig secreted during in vivo humoral immune responses
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0026687699
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Variable effects of chemical allergens on serum IgE concentration in mice. Preliminary evaluation of a novel approach to the identification of respiratory sensitisers
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Identification of chemical respiratory allergens: Dose-response relationships in the mouse IgE test
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Detection of IgE-mediated respiratory hypersensitivity in workers exposed to hexahydrophthalic anhydride
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The mouse IgE test for the identification of potential chemical respiratory allergens. Considerations of stability and controls
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Total IgE antibody in BALB/c mice after dermal exposure to chemicals
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31
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0030175425
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Characterization of chemical allergens as a function of divergent cytokine secretion profiles induced in mice
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in press
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[31] Dearman, R.J., Basketter, D.A. and Kimber, I. (1996) Characterization of chemical allergens as a function of divergent cytokine secretion profiles induced in mice. Toxicol. Appl. Pharmacol., in press.
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Toxicol. Appl. Pharmacol.
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Dearman, R.J.1
Basketter, D.A.2
Kimber, I.3
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