Increased high-affinity phosphodiesterase PDE2 gene expression in germ tubes counteracts CAP1-dependent synthesis of cyclic AMP, limits hypha production and promotes virulence of Candida albicans

Molecular Microbiology

Volumn 50, Issue 2, 2003, Pages 391-409

  Bahn, Yong Sun ^a,c   Staab, Janet ^a   Sundstrom, Paula ^a,b,d  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; ENZYME; PHOSPHODIESTERASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BUDDING; CANDIDA ALBICANS; CANDIDIASIS; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME SYNTHESIS; FUNGUS GROWTH; FUNGUS HYPHAE; FUNGUS MUTANT; GENE DISRUPTION; GENE EXPRESSION REGULATION; GERM LAYER; MOUSE; NONHUMAN; PARASITE VIRULENCE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; STARVATION;

CANDIDA ALBICANS; CELL CYCLE PROTEINS; CYCLIC AMP; CYTOSKELETAL PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HYPHAE; MICROFILAMENT PROTEINS; PHOSPHORIC DIESTER HYDROLASES;

ANIMALIA; CANDIDA; CANDIDA ALBICANS; FUNGI; MAMMALIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0142030056     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2003.03692.x     Document Type: Article

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