Advanced Glycation End Products Stimulate an Enhanced Neutrophil Respiratory Burst Mediated Through the Activation of Cytosolic Phospholipase A2 and Generation of Arachidonic Acid

Circulation

Volumn 108, Issue 15, 2003, Pages 1858-1864

  Wong, Richard K M ^b   Pettit, Andrew I ^b   Quinn, Paulene A ^b   Jennings, Sonja C ^b   Davies, Joan E ^b   Ng, Leong L ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b NONE

Author keywords

Arachidonic acid; Free radicals; Glycosylation end products, advanced; NADPH oxidase; Phospholipases

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ACETYLCYSTEINE; ADVANCED GLYCATION END PRODUCT; ARACHIDONIC ACID; CALCIUM; FREE RADICAL; INDOMETACIN; LACTONE; LIPOXYGENASE INHIBITOR; PHOSPHOLIPASE A2; PROSTAGLANDIN SYNTHASE INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRITIUM;

ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME SUBSTRATE; GEL; HUMAN; HUMAN CELL; ISOTOPE LABELING; MEMBRANE TRANSPORT; NEUTROPHIL; OXIDATION REDUCTION REACTION; PATHOGENESIS; PRIORITY JOURNAL; RESPIRATORY BURST; UPREGULATION; VASCULAR DISEASE; WESTERN BLOTTING;

ACETYLCYSTEINE; ADULT; ARACHIDONIC ACID; ARACHIDONIC ACIDS; CELLS, CULTURED; ENZYME INHIBITORS; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; INDOMETHACIN; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; OXIDATION-REDUCTION; PHOSPHOLIPASES A; PHOSPHONIC ACIDS; QUINACRINE; REACTIVE OXYGEN SPECIES; RESPIRATORY BURST; VASCULAR DISEASES;

EID: 0142021938     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000089372.64585.3B     Document Type: Article

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