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Organization of the gene encoding the human endothelin-converting enzyme (ECE-1)
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Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
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Nelson JB, Hedican SP, George DJ, et al. Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med 1995; 1:944-949.
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Nat Med
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Nelson, J.B.1
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0030047858
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Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer
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Nelson JB, Chan-Tack K, Hedican SP, et al. Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer. Cancer Res 1996; 56:663-668.
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Endothelium-derived factors as paracrine mediators of prostate cancer progression
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Pirtskhalaishvili G, Nelson JB. Endothelium-derived factors as paracrine mediators of prostate cancer progression. Prostate 2000; 44:77-87.
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Prostate
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Expression of endothelin receptor a associated with prostate cancer progression
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Gohji K, Kitazawa S, Tamada H, et al. Expression of endothelin receptor a associated with prostate cancer progression. J Urol 2001; 165:1033-1036.
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ETA receptors mediate vasoconstriction, whereas ETB receptors clear endothelin-1 in the splanchnic and renal circulation of healthy men
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Bohm F, Pernow J, Lindstrom J, et al. ETA receptors mediate vasoconstriction, whereas ETB receptors clear endothelin-1 in the splanchnic and renal circulation of healthy men. Clin Sci (Lond) 2003; 104:143-151.
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Methylation of the 5′ CpG island of the endothelin B receptor gene is common in human prostate cancer
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Nelson JB, Lee WH, Nguyen SH, et al. Methylation of the 5′ CpG island of the endothelin B receptor gene is common in human prostate cancer. Cancer Res 1997; 57:35-37.
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Pharmacological characterization of A-127722: An orally active and highly potent ETA-selective receptor antagonist
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Clinical Data and Phase III Trials with Atrasentan in Hormone Refractory Prostate Cancer
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The Endothelin-A Receptor Antagonist Atrasentan (ABT-627) Delays Clinical Progression in Hormone Refractory Prostate Cancer: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial
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Abstract #694
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Carducci MA, Nelson JB, Padley RJ, et al. The Endothelin-A Receptor Antagonist Atrasentan (ABT-627) Delays Clinical Progression in Hormone Refractory Prostate Cancer: a Multinational, Randomized, Double-Blind, Placebo-Controlled Trial. Proc Am Soc Clin Oncol 2001; 20:174a (Abstract #694).
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Effects of atrasentan on progression and survival in men with hormone refractory prostate cancer: Follow-up study M96-594
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Abstract #708
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Carducci MA, Nelson JB, Humerickhouse R, et al. Effects of atrasentan on progression and survival in men with hormone refractory prostate cancer: follow-up study M96-594. Proc Am Soc Clin Oncol 2002; 21:178a (Abstract #708).
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The Selective Endothelin-A Receptor Antagonist Atrasentan Improves Quality of Life Adjusted Time to Progression (QATTP) in Hormone Refractory Prostate Cancer Patients
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Abstract #1567
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Singh A, Padley RJ, Ashraf T, et al. The Selective Endothelin-A Receptor Antagonist Atrasentan Improves Quality of Life Adjusted Time to Progression (QATTP) in Hormone Refractory Prostate Cancer Patients. Proc Am Soc Clin Oncol 2001; 20:393a (Abstract #1567).
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The Endothelin-A Receptor Antagonist Atrasentan (ABT-627) Reduces Skeletal Remodeling Activity in Men with Advanced, Hormone Refractory Prostate Cancer
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Abstract #12
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Nelson JB, Carducci MA, Padley RJ, et al. The Endothelin-A Receptor Antagonist Atrasentan (ABT-627) Reduces Skeletal Remodeling Activity in Men with Advanced, Hormone Refractory Prostate Cancer. Proc Am Soc Clin Oncol 2001; 20:4a (Abstract #12).
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Nelson, J.B.1
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