Heart rate as a therapeutic target in heart failure?

European Heart Journal, Supplement

Volumn 5, Issue G, 2003, Pages

  Tavazzi, Luigi ^a  

^a FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

Heart failure; Heart rate; If channel; If channel antagonist; Ivabradine

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; IVABRADINE; NEUROHORMONE; UNCLASSIFIED DRUG;

CORRELATION ANALYSIS; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; HEART INFARCTION; HEART LEFT VENTRICLE FAILURE; HEART RATE; HUMAN; LIFE EXPECTANCY; MORTALITY; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0141986503     PISSN: 1520765X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1520-765X(03)90003-4     Document Type: Review

References (16)

1. Ferrari R, Rapezzi C, Lombardi F. The revival of heart rate. Eur Heart J Suppl 1999;1(suppl H):853-4.
2. Zuanetti G, Hernàndez-Bernal F, Rossi A et al. Relevance of heart rate as a prognostic factor in myocardial infarction: the GISSI experience. Eur Heart J Suppl 1999;1(suppl H):52-6.
3. Swedberg K, Eneroth P, Kjekshus J, Wilhelmsen L. The Consensus Trial Study Group. Hormone regulation of cardiovascular function in patients with severe congestive heart failure and their relation to mortality. Circulation 1990;82:1730-7.
4. St. John Sutton M, Pfeffer MA, Moye L et al. Cardiovascular death and left ventricular remodelling two years after myocardial infarction. Baseline predictors and impact of long-term use of captopril: information from the survival and ventricular enlargement (SAVE) trial. Circulation 1997; 96:3294-9.
5. Peters KG, Kienzle MG. Severe cardiomyopathy due to chronic rapidly conducted atrial fibrillation: complete recovery after restoration of sinus rhythm. Am J Med 1988;85:242-4.
6. Opasich C, Rapezzi, Lucci D et al., on behalf of the Italian Network on Congestive Heart Failure (IN-CHF) Investigators. Precipitating factors and decision-making processes of short-term worsening heart failure despite 'optimal' treatment (from the IN-CHF Registry). Am J Cardiol 2001;88:382-7.
7. Leimbach WM, Wallin BG, Victor RG et al. Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure. Circulation 1986;73:913-9.
8. Grassi G, Seravalle G, Cattaneo BM et al. Sympathetic activation and loss of reflex sympathetic control in mild congestive heart failure. Circulation 1995;92:3206-11.
9. Sandvik, Erikssen J, Ellestad M et al. Heart rate increase and maximal heart rate during exercise as predictors of cardiovascular mortality: a 16-year follow-up study of 1960 healthy men. Coron Artery Dis 1995;6:667-79.
10. Kreutz R, Struk B, Stock P et al. Evidence for primary genetic determination of heart rate regulation. Chromosomal mapping of a genetic locus in the rat. Circulation 1997;96:1078-81.
11. Gundersen T. Influence of heart size on mortality and reinfarction in patients treated with timolol after myocardial infarction. Br Heart J 1983;50:135-9.
12. Chadda K, Goldstein S, Byington R et al. Effect of propranolol after acute myocardial infarction in patients with congestive heart failure. Circulation 1986;73:503-10.
13. CIBIS-II Investigators and Committees. The Cardiac insufficiency Bisoprolol Study II: a randomised trial. Lancet 1999; 353:9-13.
14. MERIT-HF Study Group. Effect of metoprolol CR/XL in chronic heart failure: metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999;353:2001-7.
15. Packer M, Coats AJS, Fowler MB et al. Effect of carvedilol on survival in severe chronic heart failure. N Engl J Med 2001;344:1651-8.
16. Nul DR, Doval HC, Grancelli HO et al. Heart rate is a marker of amiodarone mortality reduction in severe heart failure. J Am Coll Cardiol 1997;29:1199-205.