Distribution of Adenoviral Vector in Brain after Intravenous Administration

Journal of Korean Medical Science

Volumn 18, Issue 1, 2003, Pages 108-111

  Moon, Chanil ^a   Moon, Cheil ^b   Kang, Wha Sun ^c   Jeong, Dae Chul ^c   Jin, Jong Youl ^d  

^a Eulji University   (South Korea)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Our Lady of Mercy Hospital

^d The Catholic University of Korea   (South Korea)

Author keywords

Adenoviridae; Central Nervous System; Gene Therapy; Green Fluorescent Protein

Indexed keywords

GREEN FLUORESCENT PROTEIN; RECOMBINANT PROTEIN; HYBRID PROTEIN; PHOTOPROTEIN;

ADENOVIRUS VECTOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONTROLLED STUDY; DRUG DISTRIBUTION; FEMALE; GENE TRANSFER; GRANULE CELL; HIPPOCAMPUS; INFERIOR COLLICULUS; MESENCEPHALON; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PURKINJE CELL; REPORTER GENE; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BLOOD BRAIN BARRIER; BRAIN; COMPARATIVE STUDY; CYTOLOGY; GENE VECTOR; GENETICS; GLIA; HUMAN ADENOVIRUS; INTRAVENOUS DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; NERVE CELL; PYRAMIDAL NERVE CELL; TAIL; TISSUE DISTRIBUTION; VASCULARIZATION; VIROLOGY;

ADENOVIRUSES, HUMAN; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CEREBELLUM; FEMALE; GENES, REPORTER; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; INFERIOR COLLICULUS; INJECTIONS, INTRAVENOUS; LUMINESCENT PROTEINS; MICE; MICE, INBRED BALB C; NEUROGLIA; NEURONS; PURKINJE CELLS; PYRAMIDAL CELLS; RECOMBINANT FUSION PROTEINS; TAIL; TISSUE DISTRIBUTION;

EID: 0141958644     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.2003.18.1.108     Document Type: Article

References (17)

1. Lattime LC, Gerson SL. Gene therapy of cancer. San Diego: Academic Press, 1998.
2. Du B, Wu P, Boldt-Houle DM, Terwilliger EF. Efficient transduction of human neurons with an adeno-associated virus vector. Gene Ther 1996; 3: 254-61.
3. Grant CA, Ponnazhagan S, Wang XS, Srivastava A, Li T. Evaluation of recombinant adeno-associated virus as a gene transfer vector for the retina. Curr Eye Res 1997; 16: 949-56.
4. Jomary C, Vincent KA, Grist J, Neal MJ, Jones SE. Rescue of photoreceptor function by AAV-mediated gene transfer in a mouse model of inherited retinal degeneration. Gene Ther 1997; 4: 683-90.
5. Freese A, Geller AI, Neve R. HSV-1 vector mediated neuronal gene delivery strategies for molecular neuroscience and neurology. Biochem Pharmacol 1990; 40: 2189-99.
6. Geller AI, Breakefield XO. A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons. Science 1988; 241: 1667-9.
7. Cook DG, Turner RS, Kolson DL, Lee VM, Doms RW. Vaccinia virus serves as an efficient vector for expressing heterologous proteins in human NTera 2 neurons. J Comp Neurol 1996; 374: 481-92.
8. Poeschla EM, Wong-Staal F, Looney DJ. Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors. Nat Med 1998; 4: 354-7.
9. van Praag H, Schinder AF, Christie BR, Toni N, Palmer TD, Gage FH. Functional neurogenesis in the adult hippocampus. Nature 2002; 415: 1030-4.
10. Doran SE, Ren XD, Betz AL, Pagel MA, Neuwelt EA, Roessler BJ, Davidson BL. Gene expression from recombinant viral vectors in the central nervous system after blood-brain barrier disruption. Neurosurgery 1995; 36: 965-70.
11. Raninov NG, Zimmer C, Chase M, Kramm CM, Chiocca EA, Weissleder R, Breakefield XO. Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. Hum Gene Ther 1995; 6: 1543-52.
12. Eloit M, Gilardi-Hebenstreit P, Toma B, Perricaudet M. Construction of a defective adenovirus vector expressing the pseudorabies virus glycoprotein gp50 and its use as a live vaccine. J Gen Virol 1990; 71: 2425-31.
13. Moon C, Jaberi P, Otto-Bruc A, Baehr W, Palczewski K, Ronnett GV. Calcium-sensitive participate guanylyl cyclase as a modulator of cAMP in olfactory receptor neurons. J Neurosci 1998; 18: 3195-205.
14. Moon C, Sung Y, Reddy R, Ronnett GV. Odorants induce the phosphorylation of the cAMP response element binding protein in olfactory receptor neurons. Proc Natl Acad Sci USA 1999; 96: 14605-10.
15. Jin JY, Song CW, Kim JA, Lee HJ, Kim TG, Han CW, Eom HS, Park SJ, Jeong DC, Chung NG, Kim SY, Seo YH. Expression patterns of green fluorescent protein (GFP) after intravenous injection with adenovirus vector in mouse organs. Korean J Med 2001; 61: 537-45.
16. Smith RL, Traul DL, Schaack J, Clayton GH, Staley KJ, Wilcox CL. Characterization of promoter function and cell-type-specific expression from viral vectors in the nervous system. J Virol 2000; 74: 11254-61.
17. Abe T, Wakimoto H, Bookstein R, Maneval DC, Chiocca EA, Basilion JP. Intra-arterial delivery of p53-containing adenoviral vector into experimental brain tumor. Cancer Gene Ther 2002; 9: 228-35.