The dependence of ultrasonic backscatter on trabecular thickness in human calcaneus: Theoretical and experimental results

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control

Volumn 50, Issue 8, 2003, Pages 979-986

  Wear, Keith A ^a   Laib, Andres ^b  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b SCANCO MEDICAL AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACKSCATTERING; BIOMEDICAL ENGINEERING; BONE; COMPUTERIZED TOMOGRAPHY;

HUMAN CALCANEUS; TRABECULAR THICKNESS; ULTRASONIC BACKSCATTER;

ULTRASONIC IMAGING;

ARTICLE; BIOLOGICAL MODEL; CALCANEUS; COMPARATIVE STUDY; COMPUTER SIMULATION; CYTOLOGY; ECHOGRAPHY; EVALUATION; HUMAN; IN VITRO STUDY; PHYSIOLOGY; RADIATION SCATTERING; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; VALIDATION STUDY;

CALCANEUS; COMPUTER SIMULATION; HUMANS; MODELS, BIOLOGICAL; REPRODUCIBILITY OF RESULTS; SCATTERING, RADIATION; SENSITIVITY AND SPECIFICITY;

EID: 0141957772     PISSN: 08853010     EISSN: None     Source Type: Journal    
DOI: 10.1109/TUFFC.2003.1226542     Document Type: Article

References (73)

1. NIH Consensus Statement, "Osteoporosis Prevention, Diagnosis, and Therapy," vol. 17, no. 1, Mar. 27-29, 2000.
2. C. C. Glüer, "Quantitative ultrasound techniques for the assessment of osteoporosis: Expert agreement on current status," J. Bone Miner. Res., vol. 12, pp. 1280-1288, 1997.
3. C. F. Njeh, T. Fuerst, E. Diessel, and H. K. Genant, "Is quantitative ultrasound dependent on bone structure? A reflection," Osteo. Int., vol. 12, pp. 1-15, 2001.
4. C. M. Langton, S. B. Palmer, and R. W. Porter, "The measurement of broadband ultrasonic attenuation in cancellous bone," Eng. Med., vol. 13, pp. 89-91, 1984.
5. P. Rossman, J. Zagzebski, C. Mesina, J. Sorenson, and R. Mazess, "Comparison of speed of sound and ultrasound attenuation in the os calcis to bone density of the radius, femur and lumbar spine," Clin. Phys. Physiol. Meas., vol. 10, pp. 353-360, 1989.
6. M. B. Tavakoli and J. A. Evans, "Dependence of the velocity and attenuation of ultrasound in bone on the mineral content," Phys. Med. Biol., vol. 36, pp. 1529-1537, 1991.
7. J. A. Zagzebski, P. J. Rossman, C. Mesina, R. B. Mazess, and E. L. Madsen, "Ultrasound transmission measurements through the os calcis," Calc. Tissue Int., vol. 49, pp. 107-111, 1991.
8. J. J. Kaufman and T. A. Einhorn, "Perspectives: Ultrasound assessment of bone," J. Bone. Miner. Res., vol. 8, pp. 517-525, 1993.
9. C. F. Njeh, R. Hodgskinson, J. D. Currey, and C. M. Langton, "Orthogonal relationships between ultrasonic velocity and material properties of bovine cancellous bone," Med. Eng. Phys., vol. 18, pp. 373-381, 1996.
10. C. M. Langton, C. F. Njeh, R. Hodgskinson, and J. D. Carrey, "Prediction of mechanical properties of the human calcaneus by broadband ultrasonic attenuation," Bone, vol. 18, pp. 495-503, 1996.
11. M. L. Bouxsein and S. E. Radloff, "Quantitative ultrasound of the calcaneus reflects the mechanical properties of calcaneal trabecular bone," J. Bone Miner. Res., vol. 12, pp. 839-846, 1997.
12. P. Laugier, P. Droin, A. M. Laval-Jeantet, and G. Berger, "In vitro assessment of the relationship between acoustic properties and bone mass density of the calcaneus by comparison of ultrasound parametric imaging and quantitative computed tomography," Bone, vol. 20, pp. 157-165, 1997.
13. C. Chappard, P. Laugier, B. Fournier, C. Roux, and G. Berger, "Assessment of the relationship between broadband ultrasound attenuation and bone mineral density at the calcaneus using BUA imaging and DXA," Osteo. Int., vol. 7, pp. 316-322, 1997.
14. P. H. F. Nicholson, R. Muller, G. Lowet, X. G. Cheng, T. Hildebrand, P. Ruegsegger, G. Van Der Perre, J. Dequeker, and S. Boonen, "Do quantitative ultrasound measurements reflect structure independently of density in human vertebral cancelous bone?," Bone, vol. 23, pp. 425-431, 1998.
15. D. Hans, C. Wu, C. F. Njeh, S. Zhao, P. Augat, D. Newitt, T. Link, Y. Lu, S. Majumdar, and H. K. Genant, "Ultrasound velocity of trabecular cubes reflects mainly bone density and elasticity," Calcif. Tissue Int., vol. 64, pp. 18-23, 1999.
16. H. Trebacz and A. Natali, "Ultrasound velocity and attenuation in cancellous bone samples from lumbar vertebra and calcaneus," Osteo. Int., vol. 9, pp. 99-105, 1999.
17. C. F. Njeh, D. Hans, J. Li, B. Fan, T. Fuerst, Y. Q. He, E. Tsuda-futami, Y. Lu, C. Y. Wu, and H. K. Genant, "Comparison of six calcaneal quantitative ultrasound devices: Precision and hip fracture discrimination," Osteo. Int., vol. 11, pp. 1051-1062, 2000.
18. S. R. Cummings, D. M. Black, M. C. Nevitt, W. Browner, J. Cauley, K. Ensrud, H. K. Genant, L. Palermo, J. Scott, and T. M. Vogt, "Bone density at various sites for prediction of hip fractures," Lancet, vol. 341, pp. 72-75, 1993.
19. D. Hans, P. Dargent-Molina, A. M. Schott, J. L. Sebert, C. Cormier, P. O. Kotzki, P. D. Delmas, J. M. Pouilles, G. Breart, and P. J. Meunier, "Ultrasonographic heel measurements to predict hip fracture in elderly women: The EPIDOS prospective study," Lancet, vol. 348, pp. 511-514, 1996.
20. D. C. Bauer, C. C. Gluer, J. A. Cauley, T. M. Vogt, K. E. Ensrud, H. K. Genant, and D. M. Black, "Broadband ultrasound attenuation predicts fractures strongly and independently of densitometry in older women," Arch. Intern, Med., vol. 157, pp. 629-634, 1997.
21. M. Schott, S. Weill-Engerer, D. Hans, F. Duboeuf, P. D. Delmas, and P. J. Meunier, "Ultrasound discriminates patients with hip fracture equally well as dual energy x-ray absorptiometry and independently of bone mineral density," J. Bone Miner. Res., vol. 10, pp. 243-249, 1995.
22. H. Turner, M. Peacock, L. Timmerman, J. M. Neal, and C. C. Johnston, Jr., "Calcaneal ultrasonic measurements discriminate hip fracture independently of bone mass," Osteo. Int., vol. 5, pp. 130-135, 1995.
23. C. C. Glüer, S. R. Cummings, D. C. Bauer, K. Stone, A. Pressman, A. Mathur, and H. K. Genant, "Osteoporosis: Association of recent fractures with quantitative US findings," Radiology, vol. 199, pp. 725-732, 1996.
24. P. Thompson, J. Taylor, A. Fisher, and R. Oliver, "Quantitative heel ultrasound in 3180 women between 45 and 75 years of age: Compliance, normal ranges and relationship to fracture history," Osteo. Int., vol. 8, pp. 211-214, 1998.
25. J. C. Rice, S. C. Cowin, and J. A. Bowman, "On the dependence of the elasticity and strength of cancellous bone on apparent density," J. Biomech., vol. 21, pp. 155-168, 1988.
26. V. Roberjot, P. Laugier, P. Droin, P. Giat, and G. Berger, "Measurement of integrated backscatter coefficient of trabecular bone," in Proc. IEEE Ultrason. Symp., 1996, pp. 1123-1126.
27. K. A. Wear and D. W. Armstrong, "The relationship between ultrasonic backscatter and bone mineral density in human calcaneus," IEEE Trans. Ultrason., Ferroelect., Freq. Contr., vol. 47, pp. 777-780, 2000.
28. B. K. Hoffmeister, S. A. Whitten, and J. Y. Rho, "Low megahertz ultrasonic properties of bovine cancellous bone," Bone, vol. 26, pp. 635-642, 2000.
29. B. K. Hoffmeister, S. A. Whitten, S. C. Kaste, and J. Y. Rho, "Effect of collagen and mineral content on the high frequency ultrasonic properties of human cancellous bone," Bone, Osteo. Int., vol. 13, pp. 26-32, 2002.
30. K. A. Wear and B. S. Garra, "Assessment of bone density using broadband ultrasonic backscatter," in Proc. 22nd Int. Symp. Ultrason. Imaging and Tissue Char., 1997, p. 14.
31. P. Giat, C. Chappard, C. Roux, P. Laugier, and G. Berger, "Preliminary clinical assessment of the backscatter coefficient in osteoporosis," in Proc. 22nd Int. Symp. Ultrason. Imaging and Tissue Char., 1997, p. 16.
32. P. Laugier, C. Giat, C. Chappard, C. Roux, and G. Berger, "Clinical assessment of the backscatter coefficient in osteoporosis," in Proc. IEEE Ultrason. Symp., Oct. 1997, pp. 1104-1105.
33. K. A. Wear and B. S. Garra, "Assessment of bone density using ultrasonic backscatter," Ultrasound Med. Biol., vol. 24, pp. 689-695, 1998.
34. C. Roux, V. Roberjot, R. Paorcher, S. Kolta, M. Dougados, and P. Laugier, "Ultrasonic backscatter and transmission parameters at the os calcis in postmenopausal osteoporosis," J. Bone Miner. Res., vol. 16, pp. 1353-1362, 2001.
35. K. A. Wear and D. W. Armstrong, "Relationships among calcaneal backscatter, attenuation, sound speed, hip bone mineral density, and age in normal adult women," J. Acoust. Soc. Amer., vol. 110, pp. 573-578, 2001.
36. J. J. Faran, "Sound scattering by solid cylinders and spheres," J. Acoust. Soc. Amer., vol. 23, pp. 405-418, 1997.
37. P. M. Morse and K. U. Ingard, Theoretical Acoustics. Princeton, NJ: Princeton Univ. Press, 1986.
38. K. A. Wear, "Frequency dependence of ultrasonic backscatter from human trabecular bone: Theory and experiment," J. Acoust. Soc. Amer., vol. 106, pp. 3659-3664, 1999.
39. G. Luo, J. J. Kaufman, A. Chabrera, B. Bianco, J. H. Kinney, D. Haupt, J. T. Ryaby, and R. S. Siffert, "Computational methods for ultrasonic bone assessment," Ultrasound Med. Biol., vol. 25, pp. 823-830, 1999.
40. S. Chaffai, V. Roberjot, F. Peyrin, G. Berger, and P. Laugier, "Frequency dependence of ultrasonic backscattering in cancellous bone: Autocorrelation model and experimental results," J. Acoust. Soc. Amer., vol. 108, pp. 2403-2411, 2000.
41. K. A. Wear, "Anisotropy of ultrasonic backscatter and attenuation from human calcaneus: Implications for relative roles of absorption and scattering in determining attenuation," J. Acoust. Soc. Amer., vol. 107, pp. 3474-3479, 2000.
42. P. H. F. Nicholson, R. Strelitzki, R. O. Cleveland, and M. L. Bouxsein, "Scattering of ultrasound in cancellous bone: Predictions from a theoretical model," J. Biomech., vol. 33, pp. 503-506, 2000.
43. L. Serpe and J. Y. Rho, "The nonlinear transition period of broadband ultrasound attenuation as bone density varies," J. Biomech., vol. 29, pp. 963-966, 1996.
44. C. M. Sehgal and J. F. Greenleaf, "Scattering of ultrasound by tissues," Ultrason. Imag., vol. 6, pp. 60-80, 1984.
45. C. M. Sehgal, "Quantitative relationship between tissue composition and scattering of ultrasound," J. Acoust. Soc. Amer., vol. 94, pp. 1944-1952, 1993.
46. K. D. Hausler, P. A. Rich, P. C. Smith, and E. B. Barry, "Relationships between static histomorphometry and ultrasound in the human calcaneus," Calcif. Tissue. Int., vol. 64, pp. 477-480, 1999.
47. D. Ulrich, B. van Rietbergen, A. Laib, and P. Ruegsegger, "The ability of three-dimensional structural indices to reflect mechanical aspects of trabecular bone," Bone, vol. 25, pp. 55-60, 1999.
48. M. Parfitt, M. K. Drezner, F. H. Glorieux, J. A. Kanis, H. Malluche, P. J. Neunier, S. M. Ott, and R. R. Recker, "Bone histomorphometry: Standardization of nomenclature, symbols, and units," J. Bone Miner. Res., vol. 2, pp. 595-609, 1987.
49. A. Hosokawa and T. Otani, "Ultrasonic wave propagation in bovine cancellous bone," J. Acoust. Soc. Amer., vol. 23, pp. 405-418.
50. M. E. Anderson, S. C. Soo, and G. E. Trahey, "Microcalcifications as elastic scatterers under ultrasound," IEEE Trans. Ultrason., Ferroelect., Freq. Contr., vol. 45, pp. 925-934, 1998.
51. J. K. Gong, J. S. Arnold, and S. H. Cohn, "Composition of trabecular and cortical bone," Anat. Rec., vol. 149, pp. 325-332, 1964.
52. S. Lang, "Ultrasonic method for measuring elastic coefficients of bone and results on fresh and dried bovine bones," IEEE Trans. Biomed. Eng., vol. BME-17, pp. 101-105, 1970.
53. J. L. Williams, "Ultrasonic wave propagation in cancellous and cortical bone: Predictions of some experimental results by Biot's theory," J. Acoust. Soc. Amer., vol. 92, pp. 1106-1112, 1992.
54. J. Y. Rho, R. B. Ashman, and C. H. Turner, "Young's modulus of trabecular and cortical bone material: Ultrasonic and microtensile measurements," J. Biomech., vol. 26, pp. 111-119, 1993.
55. R. B. Ashman and J. Y. Rho, "Elastic modulus of trabecular bone material," J. Biomech., vol. 21, pp. 177-181, 1988.
56. D. E. Grenoble, J. L. Katz, K. L. Dunn, R. S. Gilmore, and K. L. Murty, "The elastic properties of hard tissues and apatites," J. Biomed. Mater. Res., vol. 6, pp. 221-233, 1972.
57. E. L. Madsen, M. F. Insana, and J. A. Zagzebski, "Method of data reduction for accurate determination of acoustic backscatter coefficients," J. Acoust. Soc. Amer., vol. 76, pp. 913-923, 1984.
58. J. M. Alves, J. T. Ryaby, J. J. Kaufman, P. P. Magee, and R. S. Siffert, "Influence of marrow on ultrasonic velocity and attenuation in bovine trabecular bone," Calc. Tissue. Int., vol. 58, pp. 362-367, 1996.
59. F. Njeh and C. M. Langton, "The effect of cortical endplates on ultrasound velocity through the calcaneus: An in vitro study," Br. J. Radiol., vol. 70, pp. 504-510, 1997.
60. P. H. F. Nicholson and M. L. Bouxsein, "Bone marrow influences quantitative ultrasound measurements in human cancellous bone," Ultrasound Med. Biol., vol. 28, pp. 369-375, 2002.
61. J. A. Zagzebski, L. X. Yao, E. J. Boote, and Z. F. Lu, "Quantitative Backscatter Imaging," in Ultrasonic Scattering in Biological Tissues. K. K. Shung and G. A. Thieme, Eds, Boca Raton, FL: CRC Press, 1993, pp. 451-486.
62. K. A. Wear, B. S. Garra, and T. J. Hall, "Measurements of ultrasonic backscatter coefficients in human liver and kidney in vivo," J. Acoust. Soc. Amer., vol. 98, pp. 1852-1857, 1995.
63. R. Kuc and M. Schwartz, "Estimating the acoustic attenuation coefficient slope for liver from reflected ultrasound signals," IEEE Trans. Sonics Ultrason., vol. SU-26, pp. 353-362, 1979.
64. P. Droin, G. Berger, and P. Laugier, "Velocity dispersion of acoustic waves in cancellous bone," IEEE Trans. Ultrason., Ferroelect., Freq. Contr., vol. 45, pp. 581-592, 1998.
65. A. D. Pierce, Acoustics: An Introduction to Its Physical Principles and Applications. New York: McGraw-Hill, 1981, p. 31.
66. W. Xu and J. J. Kaufman, "Diffraction correction methods for insertion ultrasound attenuation estimation," IEEE Trans. Biomed. Eng., vol. 40, pp. 563-570, 1993.
67. P. Ruegsegger, B. Koller, and R. Muller, "A microtomographic system for the nondestructive evaluation of bone architecture," Calc. Tissue Int., vol. 58, pp. 24-29, 1996.
68. T. Hildebrand and P. Ruegsegger, "A new method for the model-independent assessment of thickness in three-dimensional images," J. Microscopy, vol. 185, pp. 67-75, 1995.
69. T. Hildebrand and P. Ruegsegger, "Quantification of bone microarchitecture with the structure model index," Comput. Methods Biomechanics Biomed. Eng., vol. 1, pp. 15-23, 1997.
70. K. A. Wear, "Fundamental precision limitations for measurements of frequency dependence of backscatter: Applications in tissue-mimicking phantoms and trabecular bone," J. Acoust. Soc. Amer., vol. 110, no. 6, pp. 3275-3282, 2001.
71. P. Laugier, F. Padilla, and F. Jenson, "Ultrasonic scattering models for cancellous bone," in 143rd Meeting of the Acoustical Society of America, J. Acoust. Soc. Amer., vol. 111, p. 2412, May 2002.
72. P. Nicholson and M. Bouxsein, "On the relationship of ultrasonic properties to density and architecture in trabecular bone," in 143rd Meeting of the Acoustical Society of America, J. Acoust. Soc. Amer., vol. 111, p. 2413, May 2002.
73. S. Chaffai, F. Peyrin, S. Nuzzo, R. Porcher, G. Berger and P. Laugier, "Ultrasonic characterization of human cancellous bone using transmission and backscatter measurements: Relationships to density and microstructure," Bone, vol. 20, pp. 229-237, 2002.