Abnormal platelet cytoskeletal assembly in hemodialyzed patients results in deficient tyrosine phosphorylation signaling

Kidney International

Volumn 57, Issue 5, 2000, Pages 1905-1914

  Díaz Ricart, Maribel ^a,b   Estebanell, Eva ^a   Cases, Aleix ^a   Calls, Jordi ^a   López Pedret, José ^a   Carretero, Marta ^a   Castillo, Ricardo ^a   Ordinas, Antonio ^a   Escolar, Ginés ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

Author keywords

Cytoskeleton; Hemodialysis; Peritoneal dialysis; Phosphotyrosine proteins; Signal transduction; Uremia

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; HEMODIALYSIS; HEMOSTASIS; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; UREMIA;

EID: 0034019829     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00040.x     Document Type: Article

References (47)

1. 1. LEWIS J, ZUCKER M, FERGUSON J: Bleeding tendency in uremia. Blood 11:1073-1076, 1956
2. 2. ANDRASSY K, RITZ E: Uremia as a cause of bleeding. Am J Nephrol 5:313-318, 1985
3. 3. DI MINNO G, MARTINEZ J, MCKEAN ML, DELAROSA J, BURKE JF, MURPHY S: Platelet dysfunction in uremia: Multifaceted defect partially corrected by dialysis. Am J Med 79:552-559, 1985
4. 4. GORDGE MP, NEILD GH: Platelet function in uraemia. Platelets 2:115-123, 1991
5. 5. IBELS LS, STEWART JH, MAHONY JF, NEALE FC, SHEIL AGR: Occlusive arterial disease in uraemic and haemodialysis patients and renal transplant recipients. Q J Med 46:197-214, 1997
6. 6. REMUZZI G, LIVIO M, MARCHIARO G, MECCA G, DE GAETANO G: Bleeding in renal failure: Altered platelet function in chronic uraemia only partially corrected by haemodialysis. Nephron 22:347-353, 1978
7. 7. CASTILLO R, LOZANO T, ESCOLAR G, REVERT L, LÓPEZ J, ORDINAS A: Defective platelet adhesion on vessel subendothelium in uremic patients. Blood 68:337-342, 1986
8. 8. ESCOLAR G, CASES A, BASTIDA E, GARRIDO M, LÓPEZ J, REVERT L, CASTILLO R, ORDINAS A: Uremic platelets have a functional defect affecting the interaction of von Willebrand factor with glycoprotein IIb-IIIa. Blood 76:1336-1340, 1990
9. 9. CASTAMAN G, RODEGHIERO F, LATTUADA A, LAGRECA G, MANNUCCI PM: Multimeric pattern of plasma and platelet von Willebrand factor is normal in uremic patients. Am J Hematol 44:266-269, 1993
10. 10. MEYER D, BAUMGARTNER HR: Role of von Willebrand factor in platelet adhesion to the subendothelium. Br J Haematol 54:1-9, 1983
11. 11. ESCOLAR G, MONTEAGUDO J, CASTILLO R, CASES A, GARRIDO M, ORDINAS A: Ultrastructural immunolocalization and morphometric quantification of platelet membrane GPIb and GPIIb-IIIa in uremic patients. Prog Clin Biol Res 283:197-201, 1988
12. 12. GRALNICK HR, MCKEOWN LP, WILLIAMS SB, SHAFER B: Plasma and platelet von Willebrand factor defects in uremia. Am J Med 85:806-810, 1989
13. 13. ZWAGINGA JJ, IJSSELDIJK MJ, BEESER-VISSER N, DE GROOT PG, Vos J, SIXMA JJ: High von Willebrand factor concentration compensates a relative adhesion defect in uremic blood. Blood 75:1498-1508, 1990
14. 14. BENIGNI A, BOCCARDO P, GALBUSERA M, MONTEAGUDO J, DE MARCO L, REMUZZI G, RUGGERI ZM: Reversible activation defect of the platelet glycoprotein IIb-IIIa complex in patients with uremia. Am J Kidney Dis 22:668-676, 1993
15. 15. GAWAZ MP, DOBOS G, SPATH M, SCHOLLEMEYER P, GURLAND HJ, MUJAIS SK: Impaired function of platelet membrane glycoprotein IIb-IIIa in end-stage renal disease. J Am Soc Nephrol 5:36-46, 1994
16. 16. ESCOLAR G, DÍAZ-RICARI M, CASES A, CASTILLO R, ORDINAS A, WHITE JG: Abnormal cytoskeletal assembly in platelets from uremic patients. Am J Pathol 143:823-831, 1993
17. 17. LINDSAY RM, FRIESEN M, ARONSTAM A, ANDRUS F, CLARK WF, LINTON AL: Improvement of platelet function by increased frequency of haemodialysis. Clin Nephrol 10:67-70, 1978
18. 18. LINDSAY RM, PRENTICE CRM, DAVIDSON JF, BURTON JA, MCNICOL GP: Haemostatic changes during dialysis associated with thrombus formation on dialysis membranes. Br Med J 4:454-458, 1972
19. 19. SULTAN Y, LONDON GM, GOLDFARB B, TOULON P, MARCHAIS SJ: Activation of platelets coagulation and fibrinolysis in patients on long-term haemosialysis: Influence of cuprophan and polyacrylonitrile membranes. Nephrol Dial Transplant 5:362-368, 1990
20. 20. WARDLE EN, PIERCY DA: Studies of contact activation of blood in haemodialysis. J Clin Pathol 25:1045-1049, 1972
21. 21. SCHMITT GW, MOAKE JL, RUDY CK, VICKS SL, HAMBURGER RJ: Alterations in hemostatic parameters during hemodialysis with dialyzers of different membrane composition and flow design: Platelet activation and factor VIII-relaled von Willebrand factor during hemodialysis. Am J Med 83:411-418, 1987
22. 22. DOCCI D, TURCI F, DEL VECCHIO C, BILANCIONI R, CENCIONI L, PRETOLANI E: Hemodialysis-associated platelet loss: Study on the relative contribution of dialyzer membrane composition and geometry. Int J Artif Organs 7:337-340, 1986
23. 23. SLOAND JA, SLOAND EM: Studies on platelet membrane glycoproteins and platelet function during hemodialysis. J Am Soc Nephrol 8:799-803, 1997
24. 24. LINDSAY RM, FRIESEN M, KOENS F, LINTON AL, OREOPOULOS D, DE VEBER G: Platelet function in patients on long term peritoneal dialysis. Clin Nephrol 6:335-339, 1976
25. 25. NENCI GG, BERRETTINI M, AGNELLI G, PARISE P, BUONCRISTIANI U, BALLATORI E: Effect of peritoneal dialysis, hemodialysis and kidney transplantation on blood platelet function. Nephron 23:287-292, 1979
26. 26. FOX JEB, LIPFERT L, CLARK EA, REYNOLDS CC, AUSTIN CD, BRUGGE JS: On the role of the platelet membrane skeleton in mediating signal transduction. J Biol Chem 268:25973-25984, 1993
27. 27. RAO GH, ESCOLAR G, WHITE JG: Epinephrine reverses the inhibitory influence of aspirin on platelet-vessel wall interactions. Thromh Res 44:65-74, 1986
28. 28. BORN GVR: The aggregation of blood platelets by adenosine diphosphate and its reversal. Nature 194:927-929, 1962
29. 29. ESCOLAR G, CASES A, VIÑAS M, CALLS J, CIRERA I, ORDINAS A: Evaluation of acquired platelet dysfunctions in uremic and cirrhotic patients using patient function analyzer (PFA-100™): Influence of hematocrit elevation. Haematologica 84:614-619, 1999
30. 30. BAUMGARTNER HR, MUGGLI R: Adhesion and aggregation: Morphological demonstration and quantitation in vivo and in vitro, in Platelets in Biology and Pathology, edited by GORDON JL, Amsterdam, North Holland Biomedical Press, 1976, pp 23-60
31. 31. DÍAZ-RICART M, TANDON NN, GÓMEZ-ORTIZ G, CARRETERO M, ESCOLAR G, ORDINAS A, JAMIESON GA: Antibodies to CD36 (GPIV) inhibit platelet adhesion to subendothelial surfaces under flow conditions. Arterioscler Thromb Vasc Biol 16:883-888, 1996
32. 32. ESCOLAR G, BASTIDA E, CASTILLO R, ORDINAS A: Development of a computer program to analyze the parameters of platelet-vessel wall interaction. Haemostasis 16:8-14, 1986
33. 33. JENNINGS LK, FOX JEB, EDWARDS HH, PHILLIPS DR: Changes in the cytoskeletal structure of human platelets following thrombin activation. J Biol Chem 256:6927-6932, 1981
34. 34. KOMETANI M, SATO T, FUJII T: Platelet cytoskeletal components involved in shape change and secretion. Thromb Res 41:801-809, 1986
35. 35. LAEMMLI UK: Cleavage of structural proteins during the assembly of the head of bacteriophage. Nature 227:680-685, 1970
36. 36. ZWAGINGA JJ, IJSSELDIJK MJ, DE GROOT PG, VOS J, DE BOS KUH. RL, SIXMA JJ: Defects in platelet adhesion and aggregate formation in uremic bleeding disorder can be attributed to factors in plasma. Arterioscler Thromb 11:733-744, 1991
37. 37. ROGER SD, PIPER J, TUCKER B, RAINE AEG, BAKER LRI, KOVACS IB: Comparison of haemostatic activity in haemodialysis and peritoneal dialysis patients with a novel technique, haemostatometry. Nephron 62:422-428, 1992
38. 38. WHITE JG: An overview of platelet structural physiology. Scanning Microscopy 1:1677-1700. 1987
39. 39. HARTWIG JH: Mechanisms of actin rearrangements mediating platelet activation. J Cell Biol 118:1421-1442, 1992
40. 40. ESTEBANELI E, DÍAZ-RICART M, LOZANO M, MAZZARA R, ESCOLAR G, ORDINAS A: Cytoskeletal reorganization after preparation of platelet concentrates, using the buffy coat method, and during their storage. Haematologica 83:112-117, 1998
41. 41. ADLER AJ, BERLYNE GM: β-Thromboglobulin and platelet factor-4 levels during hemodialysis with polyacrylonitrile. Trans Am Soc Artif Intern Organs 4:100-102, 1981
42. 42. HAKIM RM, SCHATER AI: Hemodialysis-associated platelet activation and thrombocytopenia. Am J Med 78:575-580, 1985
43. 43. GAWAZ MP, WARD RA: Effects of hemodialysis on platelet-derived thrombospondin. Kidney Int 40:257-265, 1991
44. 44. CASES A, REVERTER JC, ESCOLAR G, SANZ C, LÓPEZ-PEDRET J, REVERT L, ORDINAS A: Platelet activation on hemodialysis: Influence of dialysis membranes. Kidney Int 43(Suppl 41):S217-S220, 1993
45. 45. REVERTER JC, ESCOLAR G, SANZ C, CASES A, VILLAMOR N, NIEUWENHUIS HK, LÓPEZ J, ORDINAS A: Platelet activation during hemodialysis measured through exposure of p-selectin: Analysis by flow cytometric and ultrastructural techniques. J Lab Clin Med 124:79-85. 1994
46. 46. HARKER LA, MALPASS TW, BRANSON HE, HASSELL EA II, SLICHTER SJ: Mechanism of abnormal bleeding in patients undergoing cardiopulmonary bypass: Acquired transient platelet dysfunction associated with selective α-granule release. Blood 56:824-834, 1980
47. 47. TASSIES D, REVERTER JC, CASES A, ESCOLAR G, VILLAMOR N, LOPEZ-PEDRET J, CASTILLO R, ORDINAS A: Reticulated platelets in uremic patients: Effect of hemodialysis and continuous ambulatory peritoneal dialysis. Am J Hematol 50:161-166, 1995