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Volumn 33, Issue 9, 2003, Pages 887-901

Do metabolic pathways exist for xenobiotics? The micro-metabolism hypothesis

Author keywords

[No Author keywords available]

Indexed keywords

ANILINE DERIVATIVE; ENZYME; XENOBIOTIC AGENT;

EID: 0141953673     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250310001598221     Document Type: Article
Times cited : (14)

References (13)
  • 1
    • 0036105516 scopus 로고    scopus 로고
    • High-performance liquid chromatography-UV diode array, inductively coupled plasma mass spectrometry (ICPMS) and orthogonal acceleration time-of-flight mass spectrometry (oa-TOF-MS) applied to the simultaneous detection and identification of metabolites of 4-bromoaniline in rat urine
    • ABOU-SHAKRA, F., SAGE, A. B., CASTRO-PEREZ, J., NICHOLSON, J. K. LINDON, J. C., SCARFE, G. B and WILSON, I. D., 2002, High-performance liquid chromatography-UV diode array, inductively coupled plasma mass spectrometry (ICPMS) and orthogonal acceleration time-of-flight mass spectrometry (oa-TOF-MS) applied to the simultaneous detection and identification of metabolites of 4-bromoaniline in rat urine. Chromatographia, 55, S9-S13.
    • (2002) Chromatographia , vol.55
    • Abou-Shakra, F.1    Sage, A.B.2    Castro-Perez, J.3    Nicholson, J.K.4    Lindon, J.C.5    Scarfe, G.B.6    Wilson, I.D.7
  • 4
    • 0141846188 scopus 로고
    • Pharmacokinetics and metabolism of non-steroidal anti-inflammatory agents
    • J. W. Bridges and L. F. Chasseaud (eds), Chichester: Wiley
    • HUCKER, H. B., KWAN, K. C. and DUGGAN, D. E., 1980, Pharmacokinetics and metabolism of non-steroidal anti-inflammatory agents. In J. W. Bridges and L. F. Chasseaud (eds), Progress in Drug Metabolism (Chichester: Wiley), vol. 5, pp. 165-253.
    • (1980) Progress in Drug Metabolism , vol.5 , pp. 165-253
    • Hucker, H.B.1    Kwan, K.C.2    Duggan, D.E.3
  • 6
    • 0141917869 scopus 로고    scopus 로고
    • Detection of mono- and di-hexoses as metabolites of 4-bromoaniline using exact mass neutral loss acquisitions by HPLC-TOF-MS/MS
    • In press
    • MAJOR, H., CASTRO-PEREZ, J., NICHOLSON, J. and WILSON, I. D., In press, Detection of mono- and di-hexoses as metabolites of 4-bromoaniline using exact mass neutral loss acquisitions by HPLC-TOF-MS/MS. Xenobiotica.
    • Xenobiotica
    • Major, H.1    Castro-Perez, J.2    Nicholson, J.3    Wilson, I.D.4
  • 7
    • 0037214092 scopus 로고    scopus 로고
    • Characterisation of putative pentose-containing conjugates as minor metabolites of 4-bromoaniline present in the urine of rats following intraperitoneal administration
    • MAJOR, H., CASTRO-PEREZ, J., NICHOLSON, J. K. and WILSON, I. D., 2002, Characterisation of putative pentose-containing conjugates as minor metabolites of 4-bromoaniline present in the urine of rats following intraperitoneal administration. Rapid Communications in Mass Spectrometry, 17, 76-80.
    • (2002) Rapid Communications in Mass Spectrometry , vol.17 , pp. 76-80
    • Major, H.1    Castro-Perez, J.2    Nicholson, J.K.3    Wilson, I.D.4
  • 10
    • 0033995198 scopus 로고    scopus 로고
    • High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICPMS) for the analysis of xenobiotic metabolites in rat urine: Application to the metabolites of 4-bromoaniline
    • NICHOLSON, J. K., LINDON, J. C., SCARFE, G., WILSON, I. D., ABOU-SHAKRA, F., CASTR-PEREZ, J., EATON, A and PREECE, S., 2000, High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICPMS) for the analysis of xenobiotic metabolites in rat urine: application to the metabolites of 4-bromoaniline. Analyst, 125, 235-236.
    • (2000) Analyst , vol.125 , pp. 235-236
    • Nicholson, J.K.1    Lindon, J.C.2    Scarfe, G.3    Wilson, I.D.4    Abou-Shakra, F.5    Castr-Perez, J.6    Eaton, A.7    Preece, S.8
  • 12
    • 0018140231 scopus 로고
    • Novel drug metabolites produced by functionalisation reactions: Chemistry and toxicology
    • TESTA, B. and JENNER, P., 1978, Novel drug metabolites produced by functionalisation reactions: chemistry and toxicology. Drug Metabolism Reviews, 7, 325-369.
    • (1978) Drug Metabolism Reviews , vol.7 , pp. 325-369
    • Testa, B.1    Jenner, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.