Immunologic aspects of West syndrome and evidence of plasma inhibitory effects on T cell function

Arquivos de Neuro-Psiquiatria

Volumn 61, Issue 3 B, 2003, Pages 731-737

  Montelli, Terezinha C B ^a   Soares, Angela M V C ^b   Peraçoli, Maria Terezinha S ^b  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b IB UNESP ^*

Author keywords

CD1; CD3; CD4; CD8; Dinitrochlorobenzene; Immunoglobulins; Lennox Gastaut syndrome; Multifocal independent spike syndrome; Proliferation assay; T cells; T lymphocytes subsets; West syndrome

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; CD1 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ARTICLE; CELL ASSAY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; EPILEPSY; FEMALE; GROUPS BY AGE; HUMAN; IMMUNE DEFICIENCY; IMMUNOGLOBULIN BLOOD LEVEL; INFANT; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE TRANSFORMATION; MALE; SENSITIZATION; SKIN MANIFESTATION; SKIN TEST; SPIKE WAVE; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE; WEST SYNDROME;

EID: 0141952856     PISSN: 0004282X     EISSN: None     Source Type: Journal    
DOI: 10.1590/s0004-282x2003000500006     Document Type: Article

References (65)

1. Zhi-Sheng Liu, Qin-Wen Wang, Fang-Lin Wang, Li-Zhi Yang. Serum cytokine levels are altered in patients with West syndrome. Brain Dev 2001;23:548-551.
2. Dulac O. What is West Syndrome? Brain Dev 2001;23:447-452.
3. Shamir R, Garty BZ, Rachmel A, Kivity S, Alpert G. Risk of infection during adrenocorticotropic hormone treatment in infants with infantile spasms. Pediatr Infect Dis 1993;12:913-916.
4. Riikonen R. Infantile spasms: infectious disorders. Neuropediatrics 1993;24:274-280.
5. Lombroso CT. A prospective study of infantile spasms: clinical and therapeutic correlations. Epilepsia 1983;24:135-158.
6. Noriega-Sanchez A, Markand ON. Clinical and electroencephalographic correlation of independent multifocal spike discharges. Neurology 1976;26:667-72.
7. Benson M, Blennow G, Rosen I. Intrathecal immunoglobulin production and minor motor seizures. Acta Paediatr Scand 1987;76:147-150.
8. Duse M, Notarangelo LD, Tiberti S, Menegati E, Plebani A, Ugazio AG. Intravenous immune globulin in the treatment of intractable childhood epilepsy. Clin Exp Immunol 1996;104:71-76.
9. Eriksson K, Peltola J, Keranen T, Haapala AM, Koivikko M. High prevalence of antiphospholipid antibodies in children with epilepsy: a controlled study of 50 cases. Epilepsy Res 2001;46:129-137.
10. Lousa M, Sanchez-Alonso S, Rodriguez-Diaz R, Dalmau J. Status epilepticus with neuron-reactive serum antibodies: response to plasma exchange. Neurology 2000;54:2163-2165.
11. Wiendl H, Bien CG, Bemasconi P, et al. Glu R3 antibodies: prevalence in focal epilepsy but no specificity for Rasmussen's encephalitis. Neurology 2001;57:1511-1514.
12. Hattori H. Spontaneous remission of spasms in West syndrome. Implications of viral infections. Brain Dev 2001;23:705-707.
13. Montelli TCB. Síndrome de West, Lennox-Gastaut e epilepsia com descargas multifocais independentes: imunodeficiência e hipótese de autoimunidade. Thesis. Botucatu, 1995.
14. Montelli TCB, Mota NGS, Peraçoli MTS, Torres EA, Rezkallah-Iwasso MT. Immunological disturbances in West and Lennox-Gastaut syndromes. Arq Neuropsiquiatr 1984;42:132-139.
15. Montelli TCB, Peraçoli MTS, Soares AMVC, et al. Sensibilidade mutagênica, atividade de células natural killer e distribuição de subpopulações de linfócitos T em pacientes com síndrome de West. Resultados preliminares. Arq Neuropsiquiatr 1992;50:115.
16. Mota NGS, Rezkallah-Iwasso MT, Peraçoli MTS, Montelli TCB. Demonstration of antibody and cellular immune response to brain extract in West and Lennox-Gastaut syndromes. Arq Neuropsiquiatr 1984;42:126-131.
17. Montelli TCB, Rezkallah-Iwasso MT, Peraçoli MTS, Mota NGS. Immunologic disturbance in West and Lennox-Gastaut syndromes and in epilepsy with independent multifocal spikes. Cleveland Clin J Med 1989;56:S-285.
18. Hrachovy RA, Frost JD, Shearer JL, et al. Immunological evaluation of patients with infantile spasms. Ann Neurol, 1985;18:414.
19. Illum N, Taudorf K, Heilmann C, et al., Intravenous immunoglobulin: a single-blind trial in children with Lennox-Gastaut syndrome. Neuropediatrics 1990;21:87-90.
20. Plioplys AV, Greaves A, Yoshida W. Anti-CNS antibodies in childhood neurologic diseases. Neuropediatrics 1989;20:93-102.
21. Van Engelen BG, Weemaes CM, Renier WO, Bakkeren JA, Borm GF, Strengers PF. A dysbalanced immune system in cryptogenic Lennox-Gastaut syndrome. Scand J Immunol 1995;41:209-213.
22. Van Voorhis WC, Hair LS, Steinman RM, Kaplan G. Human dendritic cells. Enrichment and characterization from peripheral blood. J Exp Med 1980;155:1172-1187.
23. Musatti CC, Rezkallah MT, Mendes E, Mendes NF. In vivo and in vitro evaluation of cell-mediated immunity in patients with paracoccidioidomycosis. Cell Immunol 1976;24:365-378.
24. Park MI, Edwin SS, Scott JR, Branch DW. Interpretation of blocking activity in maternal serum depends on the equation used for calculation of mixed lymphocyte culture results. Clin Exp Immunol 1990;82:363-368.
25. Naspitz CK. Mecanismos básicos da resposta imunológica. In Melaragno R Filho R, Nasptiz CK. (eds). Neuroimunologia, São Paulo Sarvier, 1982:11-35.
26. Mendes E, Raphael A, Mota NGS, Mendes NF. Cell-mediated immunity in leprosy and transfer of delayed hypersensititvity reactions. J Allergy Clin Immunol 1971;53:233-239.
27. Eeg-Olofsson O, Osterland CK, Guttmann RD, et al. Immunological studies in focal epilepsy. Acta Neurol Scand 1988;78:358-368.
28. Shmatko VG, Kvetkova EA, Ereniev SI. Clinico-immunologic correlations in epilepsy. Zh Nevropatol Psikiatr Im S S Korsakova, 1984;84:814-819.
29. Margaretten NC, Warren RP. Reduced natural killer cell activity and OKT4/OKT8 ratio in epileptic patients. Immunol Invest 1986;15:159-167.
30. Bostantjsopoulou S, Hatzizisi O, Argyropoulou O, et al. Immunological parameters in patients with epilepsy. Funct Neurol 1994;9:11-15.
31. Bradstock KF, Kerr A, Grimsley P, Kirk J, Luxford C. Phenotypic characterization of immature lymphoid cells in human umbilical cord blood. Immunol Cell Biol 1988;66:387-394.
32. Sotzik F, Boyd A, Shortman K. Surface antigens of human thymocyte populations defined by CD3, CD4 and CD8 expression: CD1a is expressed by mature thymocytes but not peripheral T Cells. Immunol Lett 1993;36:101-106.
33. Caldwell CW, Poje E, Cooperstock M. Expansion of immature thymic precursor cells in peripheral blood after acute marrow suppression. Am J Clin Pathol 1991;95:824-827.
34. Seniz FN, Muftuoglu E, Batun MS, Say B. CD1+ cells in mothers of stillborn infants with neural tube defects. Am J Med Genet 1995;56:60-61.
35. Chollet-Martin S, Pialoux G, Gougerot-Pocidalo MA. Increased CD1-positive cells in peripheral blood of AIDS and ARC patients. Immunol Lett 1988;17:53-57.
36. Montelli TCB, Soares AMVC, Parise-Fortes MR, Rezkallah-Iwasso MT, Padula NMR, Peracoli MTS. Alterations of cell-mediated immune response in children with febrile seizures. Arq Neuropsiquiatr 1997;55:193-198.
37. Sugizaki MF, Peraçoli MTS, Mendes-Giannini MJS, et al. Correlation between antigenemia of paracoccidioides brasiliensis and inhibiting effects of plasma in patients with paracocidioidomycosis. Med Mycol 1999;37:277-284.
38. Chequer-Bou-Habib D, Oliveira-Neto MP, Ferreira-da-Cruz MF, Galvão-Castro B. The possible role of circulating immune complexes in the deficiency of cell-mediated immunity in paracoccidioidomycosis. Braz J Med Biol Res 1989;22:205-212.
39. Horwitz DA, Garret MA, Craig AH. Serum effects on mitogenic reactivity in subjects with systemic lupus erythematosus, rheumatoid arthritis and scleroderma: technical considerations and lack correlation with anti-lymphocyte antibodies. Clin Exp Immunol 1977;27:100-110.
40. Riely GJ, Rachmilewitz J, Koo PH, Tykocinski ML. Alpha2-macroglobulin modulates the immunoregulatory function of the lipocalin placental protein 14. Biochem J 2000;3512:503-508.
41. Bartolomei F, Boucraut J, Barrie M, et al. Cryptogenic partial epilepsies with anti-GM1 antibodies: a new form of immune-mediated epilepsy? Epilepsia 1996;37:922-926.
42. Peltola JT, Haapala A, Isojarvi JI, et al., Antiphospholipid and antinuclear antibodies in patients with epilepsy or new-onset seizure disorders. Am J Med 2000;109:712-717.
43. Xie XK, Tang LO. Observation on anti-brain antibody in serum of 110 epileptics, Chin Med J 1990;103:71-75.
44. De Graeff PA, The TH, Van Munster PJ, Out TA, Vossen JM, Zegers BJ. The primary immune response in patients with selective IgA deficiency. Clin Exp Immunol 1983;54:778-784.
45. Sanjeev Rai B, Krishnamurthy PN, Rama Rao BR. Study of cell-mediated immunity in malnourished children with DNCB skin sensitization test. Indian Pediatr 1981;18:29-33.
46. Ryniewicz B, Pawinska M. Preliminary immunological studies in spinal muscular atrophy. Eur J Pediatr 1978;128:57-60.
47. Haraldsson A, van Engelen BG, Renier WO, Bakkeren JA, Weemaes CM. Light chain ratios and concentrations of serum immunoglobulins in children with epilepsy. Epilepsy Res 1992;13:255-260.
48. Nieto M, Roldan S, Sanchez B, Candau R, Rodriguez R. Immunological study in patients with severe myoclonic epilepsy in childhood. Rev Neurol 2000;30:412-414.
49. Dambinova SA, Izykenova GA, Burov SV, Grigarenko EV, Gromov SA, The presence of autoantibodies to N-terminus domain Glu R1 subunit of AMPA receptor in the blood serum of patients with epilepsy. J Neurol Sci 1997;152:93-97.
50. Mukharinskaia VS, Antadze ZI, Kipiani MK, Vashklevich RI, Arutiunova ES. State of humoral immunity in epilepsy patients (abs). Zh Nevropatol Psikhiatr Im SS Korsakova 1980;80:1074-1077.
51. Poletaev AB, Karlov VA, Pomogaeva MV, Selifanova OP, Immunoenzyme analysis of the antigenic orientation of anti-brain autoantibodies in the serum of epileptics. Zh Nevropatol Psikhiatr Im S S Korsakova 1985;85:831-833.
52. Qu ZP, Yy LY, Lu CZ, Quiao J, Lin YX, Hong Z. A preliminary observation on auto-cholinergic synapse dysfunction in patients with different types of epilepsy. Jpn J Psychiatry Neurol 1992;46:401-403.
53. Yoshimura K, Konishi T, Kotani H, Wakiguchi H, Kurashige T. Prevalence of positive anticardiolipin antibody in benign infantile convulsion. Brain Dev 2001;23:317-320.
54. Morozov SG, Gnedenko BB, Asanova LM, Abramova OS. Autoantibodies to brain tissue antigens in epilepsy patients. Zh Nevropatol Psikhiatr Im S S Korsakova 1996;96:71-74.
55. Vlajkovic S, Jankovic BD. Experimental epilepsy in vitro: neuromodulating activity of anti-brain autoantibodies from rats exposed to electroconvulsive shock. Int J Neurosci 1991;59:205-211.
56. Karpiak SE, Serokosz M, Rapport MM. Effects of antisera to S-100 protein and to synaptic membrane fraction on maze performance and EEG. Brain Res 1976;102:313-321.
57. Karpiak SE, Graf L, Rapport MM. Antiserum to brain gangliosides produces recurrent epileptiform activity. Science 1976;194:735-737.
58. Karpiak SE, Huang YL, Rapport MM. Immunological model of epilepsy. Epileptiform activity induced by fragments of antibody to GM1 ganglioside. J Neuroimmunol 1982;3:15-21.
59. Karpiak SE, Mahadik SP, Graf L, Rapport MM. An immunological model of epilepsy: seizures induced by antibodies to GM1 gangliosides. Epilepsia 1981;22:189-196.
60. Barinaga M. Antibodies linked to rare epilepsy. Science 1995;268:362-363.
61. Rogers SW, Andrews PI, Gahring LC, et al. Autoantibodies to glutamate receptor Glu R3 in Rasmussens encephalitis. Science 1994;265:648-651.
62. Rees AJ. Autoimmunity and autoimmune disease. Brit J Anesthesiol 1979;51:13-20.
63. Jerne NK. The immune system. Sci Am 1973;229:52-60.
64. During MJ, Symes CW, Lawlor PA, et al. An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy. Science 2000;287:1453-1460.
65. Aarli JA. Epilepsy and the immune system. Arch Neurol 2000;57:1689-1692.