Why would caregivers not want to treat their relative's Alzheimer's disease?

Journal of the American Geriatrics Society

Volumn 51, Issue 10, 2003, Pages 1391-1397

  Karlawish, Jason H T ^a,d,e   Casarett, David J ^a,b,c   James, Bryan D ^a,d   Tenhave, Tom ^a   Clark, Christopher M ^a,c   Asch, David A ^a,b,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Center for Health Equity Research and Promotion   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Alzheimers Disease Center   (United States)

^e Institute on Aging   (United States)

Author keywords

Alzheimer's disease; Decision making; Treatment

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ATTITUDE; CAREGIVER; DEMENTIA SEVERITY RATING SCALE; DEPRESSION; DISEASE SEVERITY; DRUG USE; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMAN; INTERVIEW; MALE; MINI MENTAL STATE EXAMINATION; NORMAL HUMAN; NURSING HOME; QUALITY OF LIFE; RACE; RATING SCALE; RELATIVE; REVIEW; RISK ASSESSMENT; UNITED STATES;

EMPIRICAL APPROACH; MENTAL HEALTH THERAPIES;

ALZHEIMER DISEASE; CAREGIVERS; CHI-SQUARE DISTRIBUTION; CROSS-SECTIONAL STUDIES; DECISION MAKING; DISEASE PROGRESSION; FEMALE; HUMANS; INTERVIEWS; MALE; QUALITY OF LIFE; REPRODUCIBILITY OF RESULTS;

EID: 0141923675     PISSN: 00028614     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1532-5415.2003.51456.x     Document Type: Review

References (25)

1. Wolfson C, Wolfson DB, Asgharian M et al. A reevaluation of the duration of survival after the onset of dementia. N Engl J Med 2001;344:1111-1116.
2. Schulz R, O'Brien A, Bookwala J et al. Psychiatric and physical morbidity effects of dementia caregiving. Prevalence, correlates, and causes. Gerontologist 1995;35:771-791.
3. Leon J, Cheng C-K, Neumann PJ. Alzheimer's disease care. Costs and potential savings. Health Aff 1998;17:206-216.
4. Koppel R. Alzheimer's disease: The Costs to U.S. Businesses in 2002. Chicago, IL: Alzheimer's Association, 2002.
5. Brookmeyer R, Gray S, Kawas C. Projections of Alzheimer's disease in the United States and the impact of delaying disease onset. Am J Public Health 1998;88:1337-1342.
6. Sano M, Ernesto C, Thomas RG et al. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. N Engl J Med 1997;336:1216-1222.
7. Winblad B, Engedal K, Soininen H et al. A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD. Neurology 2001;57:489-495.
8. Post SG, Whitehouse PJ. Emerging antidementia drugs: A preliminary ethical view. J Am Geriatr Soc 1998;46:784-787.
9. Karlawish JH, Casarett D, Propert KJ et al. Relationship between Alzheimer's disease severity and patient participation in decisions about their medical care. J Geriatr Psych Neurol 2002;15:68-72.
10. Karlawish JHT, Klocinski J, Merz JF et al. Caregivers' preferences for the treatment of patients with Alzheimer's disease. Neurology 2000;55:1008-1014.
11. McKhann G, Drachman D, Folstein M et al. Clinical diagnosis of Alzheimer's disease. Report of the NINCDS-ADRDA work group under auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 1984;34:939-944.
12. Cornoni J, Ostfeld A, Taylor J et al. Establishing populations for epidemiologic studies of the elderly: Study design and methodology. Aging 1993;5:27-37.
13. Yesavage JA, Brink TL, Rose TL et al. Development and validation of a geriatric depression screening scale: A preliminary report. J Psychiatr Res 1983;17:37-49.
14. Vitaliano PP, Russo J, Young HM et al. The screen for caregiver burden. Gerontologist 1991;31:76-83.
15. Folstein M, Folstein S, McHugh P. 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
16. Clark C, Ewbank D. Performance of the dementia severity rating scale: A caregiver's questionnaire for rating severity in Alzheimer's disease. Alzheimer Dis Assoc Disord 1996;10:31-39.
17. Berg L. Clinical dementia rating (CDR). Psychopharmacol Bull 1988;24:637-639.
18. Logsdon RG, Gibbons LE, McCurry SM et al. Quality of life in Alzheimer's disease: Patient and caregiver reports. J Mental Health Aging 1999;5:21-32.
19. Strauss A, Corbin J. Basics of Qualitative Research: Techniques and Procedures for Developing Grounded Theory, 2nd Ed. Thousand Oaks, CA: Sage Publications, 1998.
20. Hosmer DW, Lemeshow S. Model building strategies and methods for logistic regression. Applied Logistic Regression. New York: John Wiley and Sons, 1989, pp 82-134.
21. Sachs GA. Dementia and the goals of care. J Am Geriatr Soc 1998;46:782-783.
22. Logsdon RG, Gibbons LE, Teri L et al. Quality of life in Alzheimers disease: Longitudinal perspectives [abstract]. Gerontologist 1999;39:164.
23. Karlawish JHT, Casarett D, Klocinski J et al. The relationship between caregivers' global ratings of Alzheimers disease patients' quality of life, disease severity and the caregiving experience. J Am Geriatr Soc 2001;49:1066-1070.
24. Clybum LD, Stones MJ, Hadjistavropoulos T et al. Predicting caregiver burden and depression in Alzheimer's disease. J Gerontol B Psychol Sci Soc Sci 2000;55B:S2-S13.
25. Covinsky KE, Landefeld CS, Teno J et al. Is economic hardship on the families of the seriously ill associated with patient and surrogate care preferences? The SUPPORT Investigators. Arch Intern Med 1996;156:1737-1741.