Ultrastructural and immunologic characteristics of mouse x cattle xenogeneic hybridomas originating from bovine leukemia virus-infected cattle

Veterinary Pathology

Volumn 40, Issue 4, 2003, Pages 460-464

  Saini, S S ^b   Kaushik, A ^b   Basrur, P K ^b   Yamashiro, S ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b NONE

Author keywords

Bovine immunoglobulin; Bovine leukemia virus; Hybridoma; Xenogeneic somatic cell hybridization

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; HETEROPHILE ANTIBODY; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; VIRUS ANTIGEN;

ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE ACTIVATION; BOVINE LEUKEMIA VIRUS; CATTLE DISEASE; CELL ULTRASTRUCTURE; CHROMOSOME; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; ENVELOPE GENE; GENETIC ANALYSIS; HYBRIDOMA; IMMUNOCHEMISTRY; IMMUNOPATHOLOGY; LEUKEMIA VIRUS; MOUSE; NONHUMAN; PLASMA CELL; POLYCLONAL ACTIVATION; POLYMERASE CHAIN REACTION; POLYPLOIDY; VIRUS INFECTION; VIRUS VIRULENCE; ANIMAL; ANTIBODY SPECIFICITY; CATTLE; CELL FUSION; GENETICS; IMMUNOLOGY; KARYOTYPING; METABOLISM; ULTRASTRUCTURE; VIROLOGY;

ANIMALIA; BOS TAURUS; BOVINAE; BOVINE LEUKEMIA VIRUS; C TYPE VIRUS;

ANIMALS; ANTIBODIES, HETEROPHILE; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS, VIRAL; CATTLE; CELL FUSION; HYBRIDOMAS; IMMUNOGLOBULIN M; KARYOTYPING; LEUKEMIA VIRUS, BOVINE; MICE;

EID: 0141888956     PISSN: 03009858     EISSN: None     Source Type: Journal    
DOI: 10.1354/vp.40-4-460     Document Type: Article

References (18)

1. Avrnameas S: Natural autoantibodies: from "horrr autotoxicus" to "gnothi seauton". Immunol Today 12:154-159, 1991.
2. Booman P, Tieman M, Van Zaane D, Bosma AA, De Boer GF: Construction of a bovine-murine heteromyeloma cell line; production bovine monoclonal antibodies against rotavirus and pregnant mare serum gonadotropihin. Vet Immunol Immunopathol 24:211-226, 1990
3. Borche L, Lim A, Binet JL, Dighiero G: Evidence that chronic lymphocytic leukemia B lymphocytes are frequently committed to production of natural autoantibodies. Blood 76:562-569, 1990
4. Davidson I, Katzav S, Ungar-Waron H, Eshhar Z, Haimovich J, Trainin Z: Somatic cell hybridization between bovine leukemia virus-infected lymphocytes and murine plasma cell tumors: cell fusion studies with bovine cells. Mol Immunol 7:893-899, 1982
5. Fawcett DW: The Cell, 2nd ed., pp 303-329. WB Saunders, Philadelphia, PA, 1981
6. Ferrer JF: Bovine lymphosarcoma. Adv Vet Sci Comp Med 24:1-68, 1980
7. Ferrer JF, Cabradilla C, Gupta P: Bovine leukemia: a model for viral carcinogenesis. Cold Spring Harbor Conf Cell Prolif 7:887-899, 1980
8. Ghadially FN: Ultrastructural Pathology of the Cell and Matrix, 2nd ed., pp. 315-422. Butterworths, London, UK, 1982
9. Kaushik A, Lim A, Poncet P, Ge XR, Dighiero G: Comparative analysis of natural autoantibody specificities among hybridomas originating from spleen and peritoneal cavity of adult NZB and BALB/c mice. Scand J Immunol 27:461-471, 1988
10. Kettmann R, Deschamps J, Cleuter Y, Couez D, Burny A, Marbain G: Leukemogenesis by bovine leukemia virus; proviral DNA integration and lack of RNA expression of viral long terminal repeat and 3′ proximate cellular sequences. Proc Natl Acad Sci USA 79:2465-2469, 1982
11. Kohler G, Milstein C: Continuous cultures of fused cells secreting antibody of predefined specificity. Nature (Lond) 256:495-497, 1975
12. Meirom R, Brenner J, Trainin Z: BLV infected lymphocytes exhibit two patterns of expression as determined by Ig and CD5 markers. Vet Immunol Immunopathol 36:179-186, 1993
13. Murtaugh MP, Lin GF, Haggard DL, Weber AF, Meiske JC: Detection of bovine leukemia virus in cattle by the polymerase chain reaction. J Virol Methods 33:73-85, 1991
14. Sagata N, Yasumaga T, Tsuzuku-Kawamura J, Ohishi K, Ogawa Y, Ikawa Y: Complete nucleotide sequence of the genome of bovine leukemia virus: its evolutionary relationship to other retro-viruses. Proc Natl Acad Sci USA 82:677-681, 1985
15. Saini SS, Allore B, Jacobs RM, Kaushik A: Exceptionally long CDR3H region with multiple cysteine residues in functional bovine IgM antibodies. Eur J Immunol 29:2420-2426, 1999
16. H gene family, related to mammalian group I, clan II, is identified in cattle. Mol Immunol 34:641-651, 1997
17. Yamashiro S, Clandinin MT: Myocardial ultrastructure of rat fed high and low erucic acid rapeseed oils. Exp Mol Pathol 33:55-64, 1980
18. Yamashiro S, Gilman JPW, Basrur PK, Abandowtz HM: Growth and cytogenetic characteristics of nickel-sulphide-induced rhabdomyosarcomas in rats. Acta Pathol Jpn 28:435-444, 1978