메뉴 건너뛰기




Volumn 90, Issue 2, 2003, Pages 253-266

Suppression of AP-1 constitutive activity interferes with polyomavirus MT antigen transformation ability

Author keywords

AP 1 activation; Cell transformation; Middle T antigen; Polyomavirus

Indexed keywords

AGAROSE; MT ANTIGEN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

EID: 0141864342     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10628     Document Type: Article
Times cited : (1)

References (64)
  • 2
    • 0025720735 scopus 로고
    • The role of Jun, Fos, and the AP-1 complex in cell proliferation and transformation
    • Angel P, Karin M. 1991. The role of Jun, Fos, and the AP-1 complex in cell proliferation and transformation. Biochim Biophys Acta 1072:129-157.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 3
    • 0030224378 scopus 로고    scopus 로고
    • Polyomavirus-induced malignant transformation: Comparative analysis of wild type and mutant middle T-overexpressing cell lines
    • Armelin MCS, Oliveira MLS. 1996. Polyomavirus-induced malignant transformation: Comparative analysis of wild type and mutant middle T-overexpressing cell lines. Braz J Med Biol Res 29:1133-1140.
    • (1996) Braz J Med Biol Res , vol.29 , pp. 1133-1140
    • Armelin, M.C.S.1    Oliveira, M.L.S.2
  • 4
    • 0025806587 scopus 로고
    • Ha-Ras augments cJun activity and stimulates phosphorylation of its activation domain
    • Binétruy B, Smeal T, Karin M. 1991. Ha-Ras augments cJun activity and stimulates phosphorylation of its activation domain. Nature 351:122-127.
    • (1991) Nature , vol.351 , pp. 122-127
    • Binétruy, B.1    Smeal, T.2    Karin, M.3
  • 5
    • 0030761514 scopus 로고    scopus 로고
    • The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation
    • Blaikie PA, Fournier E, Dilworth SM, Birnbaum D, Borg JP, Margolis B. 1997. The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation. J Biol Chem 272:20671-20677.
    • (1997) J Biol Chem , vol.272 , pp. 20671-20677
    • Blaikie, P.A.1    Fournier, E.2    Dilworth, S.M.3    Birnbaum, D.4    Borg, J.P.5    Margolis, B.6
  • 6
    • 0021710934 scopus 로고
    • Hygromycin B phosphotransferase as a selectable marker for DNA transfer experiments with higher eucaryotic cells
    • Blochlinger K, Diggelmann H. 1984. Hygromycin B phosphotransferase as a selectable marker for DNA transfer experiments with higher eucaryotic cells. Mol Cell Biol 4:2929-2931.
    • (1984) Mol Cell Biol , vol.4 , pp. 2929-2931
    • Blochlinger, K.1    Diggelmann, H.2
  • 7
    • 0027410854 scopus 로고
    • Suppression of oncogene induced transformation by a deletion mutant c-Jun
    • Brown PH, Alani R, Preis LH, Szabo E, Birrer MJ. 1993. Suppression of oncogene induced transformation by a deletion mutant c-Jun. Oncogene 8:877-886.
    • (1993) Oncogene , vol.8 , pp. 877-886
    • Brown, P.H.1    Alani, R.2    Preis, L.H.3    Szabo, E.4    Birrer, M.J.5
  • 8
    • 0028157457 scopus 로고
    • Mechanism of action of a dominant-negative mutant of c-Jun
    • Brown PH, Chen TK, Birrer MJ. 1994. Mechanism of action of a dominant-negative mutant of c-Jun. Oncogene 9:791-799.
    • (1994) Oncogene , vol.9 , pp. 791-799
    • Brown, P.H.1    Chen, T.K.2    Birrer, M.J.3
  • 10
    • 0029031055 scopus 로고
    • Identification of regions in polyomavirus middle T and small T antigens important for association with protein phosphatase 2A
    • Campbell KS, Auger KR, Hemmings BA, Roberts TM, Pallas DC. 1995. Identification of regions in polyomavirus middle T and small T antigens important for association with protein phosphatase 2A. J Virol 69:3721-3728.
    • (1995) J Virol , vol.69 , pp. 3721-3728
    • Campbell, K.S.1    Auger, K.R.2    Hemmings, B.A.3    Roberts, T.M.4    Pallas, D.C.5
  • 11
    • 0021364908 scopus 로고
    • Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigen
    • Carmichael GG, Schaffhausen BS, Mandel G, Liang TJ. 1984. Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigen. Proc Natl Acad Sci USA 81:679-683.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 679-683
    • Carmichael, G.G.1    Schaffhausen, B.S.2    Mandel, G.3    Liang, T.J.4
  • 12
    • 0022541589 scopus 로고
    • Recombinant retroviruses that transduce individual polyoma tumor antigens: Effects on growth and differentiation
    • Cherington V, Morgan B, Spiegelman BM, Roberts TM. 1986. Recombinant retroviruses that transduce individual polyoma tumor antigens: Effects on growth and differentiation. Proc Natl Acad Sci USA 83:4307-4311.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4307-4311
    • Cherington, V.1    Morgan, B.2    Spiegelman, B.M.3    Roberts, T.M.4
  • 13
    • 0034691011 scopus 로고    scopus 로고
    • Regulation of keratin 19 gene expression by estrogen in human breast cancer cells and identification of the estrogen responsive gene region
    • Choi I, Gudas LJ, Katzenellenbogen BS. 2000. Regulation of keratin 19 gene expression by estrogen in human breast cancer cells and identification of the estrogen responsive gene region. Mol Cell Endocrinol 164:225-237.
    • (2000) Mol Cell Endocrinol , vol.164 , pp. 225-237
    • Choi, I.1    Gudas, L.J.2    Katzenellenbogen, B.S.3
  • 14
    • 0020519557 scopus 로고
    • Polyomavirus transforming protein associates with the product of the c-src cellular gene
    • Courtneidge SA, Smith AE. 1983. Polyomavirus transforming protein associates with the product of the c-src cellular gene. Nature 303:435-439.
    • (1983) Nature , vol.303 , pp. 435-439
    • Courtneidge, S.A.1    Smith, A.E.2
  • 17
    • 0034802718 scopus 로고    scopus 로고
    • Expression of a human polyomavirus oncoprotein and tumor suppressor proteins in medulloblastomas
    • Del Valle L, Baehring J, Lorenzana C, Giordano A, Khalili K, Croul S. 2001b. Expression of a human polyomavirus oncoprotein and tumor suppressor proteins in medulloblastomas. Mol Pathol 54:331-337.
    • (2001) Mol Pathol , vol.54 , pp. 331-337
    • Del Valle, L.1    Baehring, J.2    Lorenzana, C.3    Giordano, A.4    Khalili, K.5    Croul, S.6
  • 18
    • 0036884703 scopus 로고    scopus 로고
    • Polyoma virus middle T antigen and its role in identifying cancer-related molecules
    • Dilworth SM. 2002. Polyoma virus middle T antigen and its role in identifying cancer-related molecules. Nat Rev Cancer 2:951-956.
    • (2002) Nat Rev Cancer , vol.2 , pp. 951-956
    • Dilworth, S.M.1
  • 19
    • 0028091333 scopus 로고
    • Transformation by polyomavirus middle T antigen involves the binding and tyrosine phosphorylation of Shc
    • Dilworth SM, Brewster CEP, Jones MD, Lanfrancone L, Pelicci G, Pelicci PG. 1994. Transformation by polyomavirus middle T antigen involves the binding and tyrosine phosphorylation of Shc. Nature 367:87-90.
    • (1994) Nature , vol.367 , pp. 87-90
    • Dilworth, S.M.1    Brewster, C.E.P.2    Jones, M.D.3    Lanfrancone, L.4    Pelicci, G.5    Pelicci, P.G.6
  • 20
    • 0031001540 scopus 로고    scopus 로고
    • Polyomavirus large T antigen overcomes p53 dependent growth arrest
    • Doherty J, Freund R. 1997. Polyomavirus large T antigen overcomes p53 dependent growth arrest. Oncogene 14:1923-1931.
    • (1997) Oncogene , vol.14 , pp. 1923-1931
    • Doherty, J.1    Freund, R.2
  • 21
    • 0026322935 scopus 로고
    • Generation of a large library of point mutations in polyoma middle T antigen
    • Druker BJ, Roberts TM. 1991. Generation of a large library of point mutations in polyoma middle T antigen. Nucleic Acids Res 19:6855-6861.
    • (1991) Nucleic Acids Res , vol.19 , pp. 6855-6861
    • Druker, B.J.1    Roberts, T.M.2
  • 22
    • 0025120622 scopus 로고
    • A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full and associated phosphatidylinositol kinase activity
    • Druker BJ, Ling LE, Cohen B, Roberts TM, Schaffhausen BS. 1990. A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full and associated phosphatidylinositol kinase activity. J Virol 64:4454-4461.
    • (1990) J Virol , vol.64 , pp. 4454-4461
    • Druker, B.J.1    Ling, L.E.2    Cohen, B.3    Roberts, T.M.4    Schaffhausen, B.S.5
  • 23
    • 0026672766 scopus 로고
    • Polyomavirus middle T-antigen NPTY mutants
    • Druker BJ, Sibert L, Roberts TM. 1992. Polyomavirus middle T-antigen NPTY mutants. J Virol 66:5770-5776.
    • (1992) J Virol , vol.66 , pp. 5770-5776
    • Druker, B.J.1    Sibert, L.2    Roberts, T.M.3
  • 24
    • 0030060270 scopus 로고    scopus 로고
    • Polyomavirus middle T antigen associates with the kinase domain of Src-related tyrosine kinases
    • Dunant NM, Senften M, Ballmer-Hofer K. 1996. Polyomavirus middle T antigen associates with the kinase domain of Src-related tyrosine kinases. J Virol 70:1323-1330.
    • (1996) J Virol , vol.70 , pp. 1323-1330
    • Dunant, N.M.1    Senften, M.2    Ballmer-Hofer, K.3
  • 25
    • 0026733076 scopus 로고
    • Separation of immortalization from tumor induction with polyoma large T mutants that fail to bind the retinoblastoma gene product
    • Freund R, Bronson RT, Benjamin TL. 1992. Separation of immortalization from tumor induction with polyoma large T mutants that fail to bind the retinoblastoma gene product. Oncogene 7:1979-1987.
    • (1992) Oncogene , vol.7 , pp. 1979-1987
    • Freund, R.1    Bronson, R.T.2    Benjamin, T.L.3
  • 26
    • 0027523229 scopus 로고
    • Mutation of a cysteine residue in polyomavirus middle T antigen abolishes interactions with protein phosphatase 2A, pp60c-src, and phosphatidylinositol-3 kinase, activation of c-fos expression, and cellular transformation
    • Glenn GM, Eckhart W. 1993. Mutation of a cysteine residue in polyomavirus middle T antigen abolishes interactions with protein phosphatase 2A, pp60c-src, and phosphatidylinositol-3 kinase, activation of c-fos expression, and cellular transformation. J Virol 67:1945-1952.
    • (1993) J Virol , vol.67 , pp. 1945-1952
    • Glenn, G.M.1    Eckhart, W.2
  • 27
    • 0024478233 scopus 로고
    • Association of p60fyn with middle tumor antigen in murine polyomavirus-transformed rat cells
    • Horak ID, Kawakami T, Gregory F, Robbins KC, Bolen JB. 1989. Association of p60fyn with middle tumor antigen in murine polyomavirus-transformed rat cells. J Virol 63:2343-2347.
    • (1989) J Virol , vol.63 , pp. 2343-2347
    • Horak, I.D.1    Kawakami, T.2    Gregory, F.3    Robbins, K.C.4    Bolen, J.B.5
  • 28
    • 85047697990 scopus 로고    scopus 로고
    • Cell transformation by the middle-T-antigen of polyoma virus
    • Ichaso N, Dilworth SM. 2001. Cell transformation by the middle-T-antigen of polyoma virus. Oncogene 20:7908-7916.
    • (2001) Oncogene , vol.20 , pp. 7908-7916
    • Ichaso, N.1    Dilworth, S.M.2
  • 29
    • 0023665111 scopus 로고
    • Common elements in growth factor stimulation and oncogenic transformation: 85 kDa phosphoprotein and phosphatidylinositol kinase activity
    • Kaplan DR, Whitman M, Schaffhausen B, Pallas DC, White M, Cantley L, Roberts TM. 1987. Common elements in growth factor stimulation and oncogenic transformation: 85 kDa phosphoprotein and phosphatidylinositol kinase activity. Cell 50:1021-1029.
    • (1987) Cell , vol.50 , pp. 1021-1029
    • Kaplan, D.R.1    Whitman, M.2    Schaffhausen, B.3    Pallas, D.C.4    White, M.5    Cantley, L.6    Roberts, T.M.7
  • 30
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin M. 1995. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270:16483-16486.
    • (1995) J Biol Chem , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 31
    • 0023090997 scopus 로고
    • Association of the polyomavirus middle T antigen with c-Yes protein
    • Kornbluth S, Sudol M, Hanafusa H. 1986. Association of the polyomavirus middle T antigen with c-Yes protein. Nature 325:171-173.
    • (1986) Nature , vol.325 , pp. 171-173
    • Kornbluth, S.1    Sudol, M.2    Hanafusa, H.3
  • 33
    • 0021718854 scopus 로고
    • A polyoma mutant that encodes small T antigen but not middle T antigen demonstrates uncoupling of cell surface and cytoskeletal changes associated with cell transformation
    • Liang TJ, Carmichael GG, Benjamin TL. 1984. A polyoma mutant that encodes small T antigen but not middle T antigen demonstrates uncoupling of cell surface and cytoskeletal changes associated with cell transformation. Mol Cell Biol 4:2772-2783.
    • (1984) Mol Cell Biol , vol.4 , pp. 2772-2783
    • Liang, T.J.1    Carmichael, G.G.2    Benjamin, T.L.3
  • 37
    • 0023740493 scopus 로고
    • Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: Separation of focus formation and soft agar growth in transformation assays and correlation with kinase activities in vitro
    • Morgan WC, Kaplan DR, Pallas DC, Roberts TM. 1988. Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: Separation of focus formation and soft agar growth in transformation assays and correlation with kinase activities in vitro. J Virol 62:3407-3414.
    • (1988) J Virol , vol.62 , pp. 3407-3414
    • Morgan, W.C.1    Kaplan, D.R.2    Pallas, D.C.3    Roberts, T.M.4
  • 38
    • 0031784937 scopus 로고    scopus 로고
    • Signaling from polyomavirus middle T and small T defines different roles for protein phosphatase 2A
    • Mullane KP, Ratnofsky M, Culleré X, Schaffhausen B. 1998. Signaling from polyomavirus middle T and small T defines different roles for protein phosphatase 2A. Mol Cell Biol 18:7556-7564.
    • (1998) Mol Cell Biol , vol.18 , pp. 7556-7564
    • Mullane, K.P.1    Ratnofsky, M.2    Culleré, X.3    Schaffhausen, B.4
  • 39
    • 0032507967 scopus 로고    scopus 로고
    • Mapping of polyomavirus middle T domain that is responsible for AP-1 activation
    • Oliveira MLS, Roberts TM, Druker BJ, Armelin MCS. 1998. Mapping of polyomavirus middle T domain that is responsible for AP-1 activation. Oncogene 16:2975-2982.
    • (1998) Oncogene , vol.16 , pp. 2975-2982
    • Oliveira, M.L.S.1    Roberts, T.M.2    Druker, B.J.3    Armelin, M.C.S.4
  • 44
    • 0033974322 scopus 로고    scopus 로고
    • Polyoma virus middle T and small T antigens cooperate to antagonize p53-induced cell cycle arrest and apoptosis
    • Qian W, Wiman KG. 2000. Polyoma virus middle T and small T antigens cooperate to antagonize p53-induced cell cycle arrest and apoptosis. Cell Growth Differ 11:31-39.
    • (2000) Cell Growth Differ , vol.11 , pp. 31-39
    • Qian, W.1    Wiman, K.G.2
  • 45
    • 0026178818 scopus 로고
    • T antigens role in polyomavirus transformation: c-myc but not cFos or cJun expression is a target for middle T
    • Rameh LE, Armelin MCS. 1991. T antigens role in polyomavirus transformation: c-myc but not cFos or cJun expression is a target for middle T. Oncogene 6:1049-1056.
    • (1991) Oncogene , vol.6 , pp. 1049-1056
    • Rameh, L.E.1    Armelin, M.C.S.2
  • 46
    • 0026687781 scopus 로고
    • Downregulation of JE and KC genes by glucocorticoids does not prevent the G0 → G1 transition in Balb/3T3 cells
    • Rameh LE, Armelin MCS. 1992. Downregulation of JE and KC genes by glucocorticoids does not prevent the G0 → G1 transition in Balb/3T3 cells. Mol Cell Biol 12:4612-4621.
    • (1992) Mol Cell Biol , vol.12 , pp. 4612-4621
    • Rameh, L.E.1    Armelin, M.C.S.2
  • 47
    • 0028099742 scopus 로고
    • Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant
    • Rapp UR, Troppmair J, Beck T, Birrer MJ. 1994. Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant. Oncogene 9:3493-3498.
    • (1994) Oncogene , vol.9 , pp. 3493-3498
    • Rapp, U.R.1    Troppmair, J.2    Beck, T.3    Birrer, M.J.4
  • 48
    • 0020457386 scopus 로고
    • The roles of individual polyoma virus early proteins in oncogenic transformation
    • Rassoulzadegan M, Cowie A, Glaichenhaus N, Kamen R, Cuzin F. 1982. The roles of individual polyoma virus early proteins in oncogenic transformation. Nature 300:713-718.
    • (1982) Nature , vol.300 , pp. 713-718
    • Rassoulzadegan, M.1    Cowie, A.2    Glaichenhaus, N.3    Kamen, R.4    Cuzin, F.5
  • 49
    • 0018222878 scopus 로고
    • Cellular alterations dependent upon the polyomavirus ht-t function: Separation of mitogenic from transforming capacities
    • Schlegel R, Benjamin TL. 1978. Cellular alterations dependent upon the polyomavirus ht-t function: Separation of mitogenic from transforming capacities. Cell 14:587-599.
    • (1978) Cell , vol.14 , pp. 587-599
    • Schlegel, R.1    Benjamin, T.L.2
  • 50
    • 0026773057 scopus 로고
    • Induction of c-jun protooncogene expression and transcription factor AP-1 activity by the polyoma virus middle-sized tumor antigen
    • Schöntal A, Srinivas S, Eckhart W. 1992. Induction of c-jun protooncogene expression and transcription factor AP-1 activity by the polyoma virus middle-sized tumor antigen. Proc Natl Acad Sci USA 89:4972-4976.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4972-4976
    • Schöntal, A.1    Srinivas, S.2    Eckhart, W.3
  • 51
    • 0033590588 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the mouse Ecm1 gene and its 5′ regulatory sequences
    • Smits P, Bhalerao J, Merregaert J. 1999. Molecular cloning and characterization of the mouse Ecm1 gene and its 5′ regulatory sequences. Gene 226:253-261.
    • (1999) Gene , vol.226 , pp. 253-261
    • Smits, P.1    Bhalerao, J.2    Merregaert, J.3
  • 52
    • 0041761109 scopus 로고    scopus 로고
    • Interleukin-6 increases rat metalloproteinase-13 gene expression through stimulation of activator protein 1 transcription factor in cultured fibroblasts
    • Solis-Herrugo JA, Rippe RA, Schrum LW, de La Torre P, Garcia I, Jeffrey JJ, Munoz-Yague T, Brenner DA. 1999. Interleukin-6 increases rat metalloproteinase-13 gene expression through stimulation of activator protein 1 transcription factor in cultured fibroblasts. J Biol Chem 274:30919-30926.
    • (1999) J Biol Chem , vol.274 , pp. 30919-30926
    • Solis-Herrugo, J.A.1    Rippe, R.A.2    Schrum, L.W.3    De La Torre, P.4    Garcia, I.5    Jeffrey, J.J.6    Munoz-Yague, T.7    Brenner, D.A.8
  • 53
    • 0028114305 scopus 로고
    • Polyomavirus middle sized tumor antigen modulates cJun phosphorylation and transcriptional activity
    • Srinivas S, Schönthal A, Eckhart W. 1994. Polyomavirus middle sized tumor antigen modulates cJun phosphorylation and transcriptional activity. Proc Natl Acad Sci USA 91:10064-10068.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10064-10068
    • Srinivas, S.1    Schönthal, A.2    Eckhart, W.3
  • 54
    • 0029055747 scopus 로고
    • Association of polyomavirus middle tumor antigen with phospholipase C-γ-1
    • Su W, Liu W, Schaffhausen BS, Roberts TM. 1995. Association of polyomavirus middle tumor antigen with phospholipase C-γ-1. J Biol Chem 2705:12331-12334.
    • (1995) J Biol Chem , vol.2705 , pp. 12331-12334
    • Su, W.1    Liu, W.2    Schaffhausen, B.S.3    Roberts, T.M.4
  • 57
    • 0019796925 scopus 로고
    • Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein
    • Treisman R, Novak U, Favaloro J, Kamen R. 1981. Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein. Nature 292:595-600.
    • (1981) Nature , vol.292 , pp. 595-600
    • Treisman, R.1    Novak, U.2    Favaloro, J.3    Kamen, R.4
  • 58
    • 0034641885 scopus 로고    scopus 로고
    • Transcriptional control of SPARC by v-Jun and other members of the AP1 family of transcription factors
    • Vial E, Perez S, Castellazzi M. 2000. Transcriptional control of SPARC by v-Jun and other members of the AP1 family of transcription factors. Oncogene 19:5020-5029.
    • (2000) Oncogene , vol.19 , pp. 5020-5029
    • Vial, E.1    Perez, S.2    Castellazzi, M.3
  • 59
    • 0033938194 scopus 로고    scopus 로고
    • Expression of Jun family members in human colorectal adenocarcinoma
    • Wang H, Birkenbach M, Hart J. 2000. Expression of Jun family members in human colorectal adenocarcinoma. Carcinogenesis 21:1313-1317.
    • (2000) Carcinogenesis , vol.21 , pp. 1313-1317
    • Wang, H.1    Birkenbach, M.2    Hart, J.3
  • 61
    • 0032585649 scopus 로고    scopus 로고
    • Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation
    • Watts RG, Huang C, Young MR, Li JJ, Dong Z, Pennie WD, Colburn NH. 1998. Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation. Oncogene 17:3493-3498.
    • (1998) Oncogene , vol.17 , pp. 3493-3498
    • Watts, R.G.1    Huang, C.2    Young, M.R.3    Li, J.J.4    Dong, Z.5    Pennie, W.D.6    Colburn, N.H.7
  • 62
    • 0021828496 scopus 로고
    • Association of phosphatidylinositol kinase activity with polyoma middle T competent for transformation
    • Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM. 1985. Association of phosphatidylinositol kinase activity with polyoma middle T competent for transformation. Nature 315:239-242.
    • (1985) Nature , vol.315 , pp. 239-242
    • Whitman, M.1    Kaplan, D.R.2    Schaffhausen, B.3    Cantley, L.4    Roberts, T.M.5
  • 63
    • 0033521651 scopus 로고    scopus 로고
    • cJun regulates cell cycle progression and apoptosis by distinct mechanisms
    • Wisdom R, Johnson RS, Moore C. 1999. cJun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J 18:188-197.
    • (1999) EMBO J , vol.18 , pp. 188-197
    • Wisdom, R.1    Johnson, R.S.2    Moore, C.3
  • 64
    • 0034680011 scopus 로고    scopus 로고
    • High levels of phosphorylated c-Jun, Fra-1, Fra-2, and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model
    • Zoumpourlis V, Paraskevi P, Linardopoulos S, Gillespie D, Balmain A, Pintzas A. 2000. High levels of phosphorylated c-Jun, Fra-1, Fra-2, and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model. Oncogene 19:4011-4021.
    • (2000) Oncogene , vol.19 , pp. 4011-4021
    • Zoumpourlis, V.1    Paraskevi, P.2    Linardopoulos, S.3    Gillespie, D.4    Balmain, A.5    Pintzas, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.