Fetal nucleated red blood cells in peripheral blood of pregnant women: Detection and determination of location on a slide using laser-scanning cytometry

Prenatal Diagnosis

Volumn 23, Issue 9, 2003, Pages 710-715

  Hennerbichler, Simone ^a   Kroisel, Peter M ^a   Zierler, Hannelore ^a   Pertl, Barbara ^a   Wintersteiger, Reinhold ^a   Dohr, Gottfried ^a   Sedlmayr, Peter ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

Erythroblasts; Fetal cells in maternal blood; FISH; Laser scanning cytometry; Noninvasive prenatal diagnosis

Indexed keywords

CD71 ANTIGEN; DNA; HEMOGLOBIN C;

AMNIOCENTESIS; ARTICLE; CELL DENSITY; CELL SELECTION; CLINICAL ARTICLE; ERYTHROBLAST; ERYTHROCYTE; FEMALE; FETUS; FETUS BLOOD; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LASER MICROSCOPY; MALE; NUCLEATED RED BLOOD CELL; PERIPHERAL CIRCULATION; POLYMERASE CHAIN REACTION; PREGNANCY; PRIORITY JOURNAL; TWINS; Y CHROMOSOME;

ADULT; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, Y; ERYTHROBLASTS; FEMALE; HUMANS; IMAGE CYTOMETRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MATERNAL AGE; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; PREGNANCY, HIGH-RISK; PRENATAL DIAGNOSIS;

EID: 0141857558     PISSN: 01973851     EISSN: None     Source Type: Journal    
DOI: 10.1002/pd.668     Document Type: Article

References (36)

1. Al-Mufti R, Hambley H, Farzaneh F, Nicolaides KH. 1999. Investigation of maternal blood enriched for fetal cells: role in screening and diagnosis of fetal trisomies. Am J Med Genet 85: 66-75.
2. Ariga H, Ohto H, Busch MP. et al. 2001. Kinetics of fetal cellular and cell-free DNA in the maternal circulation during and after pregnancy: implications for noninvasive prenatal diagnosis. Transfusion 41: 1524-1530.
3. Bianchi DW, Flint AF, Pizzimenti MF, Knoll JHM, Latt SA. 1990. Isolation of fetal DNA from nucleated erythrocytes in maternal blood. Proc Natl Acad Sci USA 87: 3279-3283.
4. Bianchi DW, Mahr A, Zickwolf GK, Houseal TW, Flint AF, Klinger KW. 1992. Detection of fetal cells with 47,XY,+21 karyotype in maternal peripheral blood. Hum Genet 90: 368-370.
5. Bianchi DW, Simpson JL, Jackson LG, et al. 2002. Fetal gender and aneuploidy detection using fetal cells in maternal blood: analysis of NIFTY I data. Prenat Diagn 22: 609-615.
6. Bianchi DW, Williams JM, Sullivan LM, Hanson FW, Klinger KW, Shuber AP. 1997. PCR quantitation of fetal cells in maternal blood in normal and aneuploid pregnancies. Am J Hum Genet 61: 822-829.
7. Bianchi DW, Zickwolf GK, Weil GJ, Sylvester S, DeMaria MA. 1996. Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum. Proc Natl Acad Sci USA 93: 705-708.
8. Burastero SE, Galbiati S, Vassallo A, et al. 2003. Cellular microchimerism as a lifelong physiologic status in parous women: an immunologic basis for its amplification in patients with systemic sclerosis. Arthritis Rheum 48: 1109-1116.
9. Chen H, Griffin DK, Jestice K, Hackett G, Cooper J, Ferguson-Smith MA. 1998. Evaluating the culture of fetal erythroblasts from maternal blood for non-invasive prenatal diagnosis. Prenat Diagn 18: 883-892.
10. Cheung M-C, Goldberg JD, Kan YW. 1996. Prenatal diagnosis of sickle cell anaemia and thalassaemia by analysis of fetal cells in maternal blood. Nat Genet 14: 264-268.
11. DeMaria MA, Zheng Y-L, Zhen D, Weinschenk NM, Vadnais TJ, Bianchi DW. 1996. Improved fetal nucleated erythrocyte sorting purity using intracellular antifetal hemoglobin and Hoechst 33342. Cytometry 25: 37-45.
12. Elias S, Price J, Dockter M, et al. 1992. First trimester prenatal diagnosis of trisomy 21 in fetal cells from maternal blood [letter]. Lancet 340: 1033.
13. Elias S, Simpson JL. 1993. Amniocentesis. In Essentials of Prenatal Diagnosis, Simpson JL, Elias S (eds). Churchill Livingstone: New York; 27-44.
14. Gänshirt-Ahlert D, Börjesson-Stoll R, Burschyk M, et al. 1993. Detection of fetal trisomies 21 and 18 from maternal blood using triple gradient and magnetic cell sorting. Am J Reprod Immunol 30: 194-201.
15. Hennerbichler S, Méhes G, Schmied R, et al. 2002b. Detection and relocation of rare events: A comparative study using the laser scanning cytometer and the metafer/RCDetect microscope scanning system. J Biochem Biophys Methods 53: 109-115.
16. Hennerbichler S, Schmied R, Petek E, et al. 2002a. Detection and relocation of cord blood nucleated red blood cells by laser scanning cytometry. Cytometry 48: 87-92.
17. Jackson LG, Wapner RJ. 1993. Chorionic villous sampling. In Essentials of Prenatal Diagnosis, Simpson JL, Elias S (eds). Churchill Livingstone: New York; 45-61.
18. Klein CA, Schmidt-Kittler O, Schardt JA, Pantel K, Speicher MR, Riethmüller G. 1999. Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells. Proc Natl Acad Sci USA 96: 4494-4499.
19. Klein CA, Seidl S, Petat-Dutter K, et al. 2002. Combined transcriptome and genome analysis of single micrometastatic cells. Nat Biotechnol 20: 387-392.
20. Krabchi K, Gros Louis F, Yan J, et al. 2001. Quantification of all fetal nucleated cells in maternal blood between the 18th and 22nd weeks of pregnancy using molecular cytogenetic techniques. Clin Genet 60: 145-150.
21. Lo Y-MD, Morey AL, Wainscoat JS, Fleming KA. 1994. Culture of fetal erythroid cells from maternal peripheral blood. Lancet 344: 264-265.
22. Oosterwijk JC, Mesker WE, Ouwerkerk-van-Velzen MCM, et al. 1998. Fetal cell detection in maternal blood: a study in 236 samples using erythroblast morphology, DAB and HbF staining, and FISH analysis. Cytometry 32: 178-185.
23. Parano E, Falcidia E, Grillo A, et al. 2001. Noninvasive prenatal diagnosis of chromosomal aneuploidies by isolation and analysis of fetal cells from maternal blood. Am J Med Genet 101: 262-267.
24. Pearson HA. 1967. Life-span of the fetal red blood cell. J Pediatr 70: 166-171.
25. Rodríguez de Alba M, Palomino P, González-González C, et al. 2001. Prenatal diagnosis on fetal cells from maternal blood: practical comparative evaluation of the first and second trimesters. Prenat Diagn 21: 165-170.
26. Samura O, Pertl B, Sohda S, et al. 2000. Female fetal cells in maternal blood: use of DNA polymorphisms to prove origin. Hum Genet 107: 28-32.
27. Savion S, Carp H, Shepshelovich J, et al. 1997. Use of antibodies against the human antigen of erythroblasts for the detection of nucleated erythrocytes in the maternal circulation. Biol Neonate 71: 126-130.
28. Sekizawa A, Kimura T, Sasaki M, Nakamura S, Kobayashi R, Sato T. 1996. Prenatal diagnosis of Duchenne muscular dystrophy using a single fetal nucleated erythrocyte in maternal blood. Neurology 46: 1350-1353.
29. Troeger C, Holzgreve W, Hahn S. 1999a. A comparison of different density gradients and antibodies for enrichment of fetal erythroblasts by MACS. Prenat Diagn 19: 521-526.
30. Troeger C, Zhong XY, Burgemeister R, et al. 1999b. Approximately half of the erythroblasts in maternal blood are of fetal origin. Mol Hum Reprod 5: 1162-1165.
31. Tutschek B, Reinhard J, Kögler G, Wernet P, Niederacher D. 2000. Clonal culture of fetal cells from maternal blood. Lancet 356: 1736-1737.
32. Valerio D, Aiello R, Altieri V, Malato AP, Fortunato A, Canazio A. 1996. Culture of fetal erythroid progenitor cells from maternal blood for non-invasive prenatal genetic diagnosis. Prenat Diagn 16: 1073-1082.
33. Wachtel SS, Sammons D, Manley M, et al. 1996. Fetal cells in maternal blood: recovery by charge flow separation. Hum Genet 98: 162-166.
34. Wang J-Y, Zhen DK, Zilberstein ME, Falco VM, Bianchi DW. 2000. Non-invasive exclusion of fetal aneuploidy in an at-risk couple with a balanced translocation. Mol Hum Reprod 6: 103-106.
35. Zhen DK, Wang JY, Falco VM, Weber W, Delli-Bovi L, Bianchi DW. 1998. Poly-FISH: a technique of repeated hybridizations that improves cytogenetic analysis of fetal cells in maternal blood. Prenat Diagn 18: 1181-1185.
36. Zhong XY, Holzgreve W, Li JC, Aydinli K, Hahn S. 2000. High levels of fetal erythroblasts and fetal extracellular DNA in the peripheral blood of a pregnant woman with idiopathic polyhydramnios: case report. Prenat Diagn 20: 838-841.