Novel core(polyester)-shell(polysaccharide) nanoparticles: Protein loading and surface modification with lectins

Journal of Controlled Release

Volumn 92, Issue 1-2, 2003, Pages 103-112

  Rodrigues, J S ^a   Santos Magalhaes N S ^a   Coelho, L C B B ^a   Couvreur, P ^b   Ponchel, G ^b   Gref, R ^b  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Bauhinia monandra; Caprolactone; Copolymer; Core corona nanoparticle; Dextran; Lectin; Lens culinaris

Indexed keywords

POLYESTERS; POLYSACCHARIDES; PROTEINS; SURFACE TREATMENT;

LECTINS;

NANOSTRUCTURED MATERIALS;

BOVINE SERUM ALBUMIN; COPOLYMER; DEXTRAN POLY(EPSILON CAPROLACTONE) COPOLYMER; LECTIN; NANOPARTICLE; POLYCAPROLACTONE; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ADSORPTION; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; ENCAPSULATION; HEMAGGLUTINATION; HUMAN; HUMAN CELL; LENTIL; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN MODIFICATION;

EID: 0141853264     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(03)00296-7     Document Type: Article

References (20)

1. Janes K.A., Calvo P., Alonso M.J. Polysaccharide colloidal particles as delivery systems for macromolecules. Adv. Drug Deliv. Rev. 47:2001;83-97.
2. Kompella U.B., Lee V.H.L. Delivery systems for penetration enhancement of peptide and protein drugs: design considerations. Adv. Drug Deliv. Rev. 46:2001;211-245.
3. Meyenburg S., Lilie H., Panzner S., Rudolph R. Fibrin encapsulated liposomes as protein delivery system studies on the in vitro release behavior. J. Controlled Release. 69:2000;159-168.
4. Quellec P., Gref R., Perrin L., Dellacherie E., Sommer F., Verbavatz J.M., Alonso M.J. Protein encapsulation within PEG-coated nanospheres. I. Physico-chemical characterization. J. Biomed. Mater. Res. 42:1998;45-54.
5. Tobio M., Gref R., Sanchez A., Langer R., Alonso M.J. Stealth PLA-PEG nanoparticles as protein carriers for nasal administration. Pharmaceut. Res. 15:1998;274-279.
6. Jung T., Kamm W., Breitenbach A., Kaiserling E., Xiao J.X., Kissel T. Biodegrable nanoparticules for oral delivery of peptides: is there a role for polymers to affect mucosal uptake? Eur. J. Pharm. Biopharm. 50:2000;147-160.
7. Zambaux M.F., Bonneaux F., Gref R., Dellacherie E., Vigneron C. Preparation and characterization of protein C-loaded PLA nanoparticles. J. Controlled Release. 60:1999;179-188.
8. Hussain N., Jani P.U., Florence A.T. Enhanced oral uptake of tomato lectin-conjugated nanoparticles in the rat. Pharm. Res. 14:1997;613-618.
9. Ezpeleta I., Arangoa M.A., Irache J.M., Stainmesse S., Chabenat C., Popineau Y., Orecchioni A.M. Preparation of Ulex europaeus lectin-gliadin nanoparticle conjugates and their interaction with gastrointestinal mucus. Int. J. Pharm. 191:1999;25-32.
10. De Wolf F.A., Brett G.M. Ligand-binding proteins: their potential for application in systems for controlled delivery and uptake of ligands. Pharmacol. Rev. 52:2000;207-236.
11. R. Gref, P. Couvreur, G. Barratt, E. Mysiakine, Surface-engineered nanoparticles for multiple ligand coupling, Biomaterials (in press).
12. Sharon N., Lis H. Carbohydrate Specificity in Lectins. 1989;Chapman and Hall, London.
13. Yamazaki N., Kojima S., Bovin N.V., André S., Gabius S., Gabius H.J. Endogenous lectins as targets for drug delivery. Adv. Drug Deliv. Rev. 43:2000;225-244.
14. Ponchel G., Irache J.M. Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract. Adv. Drug Deliv. Rev. 34:1998;191-219.
15. Gref R., Rodrigues J.S., Couvreur P. Polysaccharide grafted with polyesters: novel amphiphilic copolymers for biomedical applications. Macromolecules. 35:2003;9861-9867.
16. Coelho L.C.B.B., Silva M.B.R. Simple method to purify milligram quantities of the galactose-specific lectin from the leaves of Bauhinia monandra. Phytochem. Anal. 11:2000;1-6.
17. Vauthier C., Shchmidt C., Couvreur P. Measurement of the density of polymeric nanoparticles drug carriers by isopycnic centrifugation. J. Nanopart. Res. 1:1999;411-418.
18. L Peterson G. A simplification of the protein assay Method of Lowry et al., which is more generally applicable. Anal. Biochem. 83:1997;346-356.
19. Correia M.T.S., Coelho L.C.B.B. Purification of glucose/mannose specific lectin, isoform 1, from seeds of Cratylia mollis Mart. (Camaratu Bean). Appl. Biochem. Biotechnol. 55:1995;261-273.
20. Quellec P., Gref R., Dellacherie E., Sommer F., Tran M., Alonso M.J. Protein encapsulation within poly(ethylene glycol)-coated nanospheres. II. Controlled release properties. J. Biomed. Mater. Res. 47:(3):1999;388-395.