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Volumn 58, Issue 9, 2003, Pages 651-653
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Concentration dependent stereoselectivity of propafenone N-depropylation metabolism with human hepatic recombinant CYP1A2
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Author keywords
[No Author keywords available]
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Indexed keywords
CYTOCHROME P450 1A2;
DEPROPYLPROPAFENONE;
LIVER ENZYME;
PROPAFENONE;
RECOMBINANT ENZYME;
ANIMAL CELL;
ANIMAL CELL CULTURE;
ARTICLE;
CELL STRAIN;
CHEMICAL REACTION;
CHIRALITY;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
CULTURE MEDIUM;
DEPROPYLATION;
DRUG DETERMINATION;
DRUG DISPOSITION;
DRUG ELIMINATION;
DRUG INTERACTION;
DRUG METABOLISM;
DRUG STRUCTURE;
ENANTIOMER;
ENANTIOSELECTIVITY;
ENZYME ACTIVITY;
ENZYME SUBSTRATE;
EXPERIMENTAL MODEL;
HUMAN;
IC 50;
IN VITRO STUDY;
ISOMER;
NONHUMAN;
PHARMACOKINETICS;
PROTEIN EXPRESSION;
REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
SEPARATION TECHNIQUE;
STEREOCHEMISTRY;
TRANSGENE;
ANTI-ARRHYTHMIA AGENTS;
BIOTRANSFORMATION;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CHROMATOGRAPHY, LIQUID;
CYTOCHROME P-450 CYP1A2;
HUMANS;
LIVER;
PROPAFENONE;
RECOMBINANT PROTEINS;
STEREOISOMERISM;
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EID: 0141842760
PISSN: 00317144
EISSN: None
Source Type: Journal
DOI: None Document Type: Article |
Times cited : (14)
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References (12)
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