The influence of CYP2D6 activity on the kinetics of propafenone enantiomers in Chinese subjects

British Journal of Clinical Pharmacology

Volumn 47, Issue 5, 1999, Pages 553-556

  Cai, W M ^a   Chen, B ^a   Cai, M H ^a   Chen, Y ^b   Zhang, Y D ^b  

^a JINLING HOSPITAL   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Chinese; CYP2D6; Enantiomer; Pharmacokinetics; Phenotype; Propafenone

Indexed keywords

CYTOCHROME P450; DEXTROMETHORPHAN; PROPAFENONE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CHINESE; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG METABOLISM; ENANTIOMER; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NAUSEA; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PHENOTYPE; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STOMACH DISEASE; VERTIGO;

ADMINISTRATION, ORAL; ADULT; ANTI-ARRHYTHMIA AGENTS; AREA UNDER CURVE; CHINA; CYTOCHROME P-450 CYP2D6; DIZZINESS; FEMALE; HUMANS; MALE; MIDDLE AGED; NAUSEA; PROPAFENONE; STEREOISOMERISM; STOMACH DISEASES;

EID: 0032955843     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1999.00932.x     Document Type: Article

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