Regional variation in the use of medications by older Canadians - A persistent and incompletely understood phenomena

Pharmacoepidemiology and Drug Safety

Volumn 12, Issue 7, 2003, Pages 575-582

  Hogan, D B ^a,b   Maxwell, C J ^a   Fung, T S ^a   Ebly, E M ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b Health Sciences Centre Calgary   (Canada)

Author keywords

Medication use in seniors; Regional differences in medications

Indexed keywords

ACETYLSALICYLIC ACID; ANALGESIC AGENT; ANTIDEPRESSANT AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; ANXIOLYTIC AGENT; BENZODIAZEPINE DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARDIAC AGENT; CORTICOSTEROID; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; GLUCOCORTICOID; HERBACEOUS AGENT; INSULIN; MINERAL; MINERALOCORTICOID; MONOAMINE OXIDASE INHIBITOR; NEUROLEPTIC AGENT; NITRATE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; ORAL ANTIDIABETIC AGENT; PARACETAMOL; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VITAMIN;

AGED; AGING; ALTERNATIVE MEDICINE; ARTHRITIS; ARTICLE; CANADA; CONTROLLED STUDY; DATA ANALYSIS; DEPRESSION; DIABETES MELLITUS; DRUG UTILIZATION; FEMALE; GEOGRAPHY; HEART INFARCTION; HUMAN; HYPERTENSION; LINEAR REGRESSION ANALYSIS; LOGISTIC REGRESSION ANALYSIS; LONGITUDINAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; RHEUMATIC DISEASE; STATISTICAL SIGNIFICANCE;

ACETAMINOPHEN; AGED; BENZODIAZEPINES; CANADA; COHORT STUDIES; DRUGS, CHINESE HERBAL; DRUGS, NON-PRESCRIPTION; FEMALE; GEOGRAPHY; HEALTH SERVICES FOR THE AGED; HUMANS; LONGITUDINAL STUDIES; MALE; NITRATES; SELF MEDICATION;

EID: 0141840668     PISSN: 10538569     EISSN: None     Source Type: Journal    
DOI: 10.1002/pds.803     Document Type: Article

References (29)

1. Willcox SM, Himmelstein DU, Woodlander S. Inappropriate drug-prescribing for the community-dwelling elderly. JAMA 1994; 272: 292-296.
2. Chen YF, Dewey ME, Avery AJ. Self-reported medication use for older people in England and Wales. J Clin Pharm Ther 2001; 26: 129-140.
3. Hogan DB, Ebly EM, Fung TS. Regional variations in use of potentially inappropriate medications by Canadian seniors participating in the Canadian Study of Health & Aging. Can J Clin Pharmacol 1995; 2: 167-174.
4. Au DH, McDonell MB, Martin DC, Fihn SD. Regional variations in health status. Med Care 2001; 39: 879-888.
5. Obisesan To, Vargas CM, Gillum RF. Geographic variation in stroke risk in the United States. Region, urbanization, and hypertension in the Third National Health and Nutrition Examination Survey. Stroke 2000; 31: 19-25.
6. Morris RW, Whincup RH, Lampe FC, Walker M, Wannamethee SG, Shaper AG. Geographic variation in the incidence of coronary heart disease in Britain: the contribution of established risk factors. Heart 2001; 86: 277-283.
7. Blanchard JF, Bernstein CN, Wajda A, Rawsthrone P. Small-area variations and sociodemographic correlates for the incidence of Crohn's disease and ulcerative colitis. Am J Epidemiol 2001; 154: 328-335.
8. Anis AH, Guh D, Wang X-H. A dog's breakfast: prescription drug coverage varies widely across Canada. Med Care 2001; 39: 315-316.
9. O'Connor GT, Quinton HB, Traven ND, et al. Geographic variation in the treatment of acute myocardial infarction: the Cooperative Cardiovascular Project. JAMA 1991; 282: 627-633.
10. Lassila HC, Stoehr GP, Ganguli M, et al. Use of prescription medications in an elderly rural population: the MOVIES project. Ann Pharmacother 1996; 30: 589-595.
11. Massie BM, Cleland JF, Armstron PW, et al. Regional differences in the characteristics and treatment ofpatients participating in an international heart failure trial. The Assesssment of Treatment with Lisonopril and Survival (ATLAS) Trial Investigators. J Card Fail 1998; 4: 3-8.
12. Canadian Study of Health and Aging. Canadian Study of Health and Aging-study methods and prevalence of dementia. Can Med Assoc J 1994; 150: 899-913.
13. Teng EL. The modified mini-mental state (3MS) examination. J Clin Psychiatry 1987; 48: 314-318.
14. The Canadian Study of Health and Aging Working Group: the incidence of dementia in Canada. Neurology 2000; 55: 66-73.
15. Sheikh JI, Yesavage. Geriatric Depression Scale (GDS): recent evidence and development of a shorter version. In: Clinical Gerontology: A Guide to Assessment and Intervention, Brink TL (ed.). Haworth Press, New York, NY, 1986; 165.
16. Walop W, Semechuk M. Coding of drugs used by respondents of the Canadian Study of Health and Aging. Can J Clin Pharmacol 2002; 9: 64-68.
17. Gilmore J, Wannell B, Wilkins R, et al. How Healthy are Canadians? Health Rep 1999; 11: Catalogue no. 82-003. Statistics Canada.
18. Astin JA, Pelletier KR, Marie A, Haskell WL. Complementary and alternative medicine use among elderly persons: one year analysis of a Blue Shield Medicare supplement. J Gerontol A Biol Sci Med Sci 2000; 55: M4-9.
19. Anis AH, Carruthers G, Carter AO, Kierulf J. Variability in prescription drug utilization: issues for research. Can Med Assoc J 1996; 154: 635-640.
20. Coyte PC, Hawker G, Wright JG. Variations in knee replacement utilization rates and the supply of health professionals in Ontario, Canada. J Rheumatol 1996; 23: 1214-1220.
21. Carriere Y, Pelletier L. Factors underlying the institutionalization of elderly persons in Canada. J Gerontol B Psychol Sci Soc Sci 1995; 50: S164-172.
22. Grootendorst P. Beneficiary cost sharing under Canadian provincial prescription drug benefit programs: history and assessment. Can J Clin Pharmacol 2002; 9: 79-99.
23. Laupacis A. Inclusion of drugs in provincial drug benefit programs: who is making these decisions, and are they the right ones? Can Med Assoc J 2002; 166: 44-47.
24. Gregoire JP, MacNeil P, Skilton K, et al. Inter-provincial variation in government drug formularies. Can J Pub Health 2001; 92: 307-312.
25. Millar W. Use of alternative health care practitioners by Canadians. Can J Pub Health 1997; 88: 154-158.
26. CTV/Angus Reid Group Poll. Use of Alternative Medicines and Practices. September 1997.
27. Eisenberg DM, Davis RB, Ettner SL, et al. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA 1998; 280: 1569-1575.
28. Kessler RC, Davis RB, Foster DF, et al. Long-term trends in the use of complementary and alternative medical therapies in the United States. Ann Intern Med 2001; 135: 262-268.
29. Rajendran PR, Thompson RE, Reich SG. The use of alternative therapies by patients with Parkinson's disease. Neurology 2001; 57: 790-794.