Variability in prescription drug utilization: Issues for research

CMAJ. Canadian Medical Association Journal

Volumn 154, Issue 5, 1996, Pages 635-640

  Anis, Aslam H ^a,b,f   Carruthers, S George ^c   Carter, Anne O ^d   Kierulf, Jacqueline ^e  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b ST PAUL S HOSPITAL   (Canada)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

^d CMAJ   (Canada)

^e Burrard Building ^*

^f Health Research Department   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL PRACTICE; COST CONTROL; DATA BASE; DRUG COST; DRUG USE; HUMAN; MEDICAL LITERATURE; PHYSICIAN; PRESCRIPTION;

EID: 0029864708     PISSN: 08203946     EISSN: 14882329     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. National Health Expenditures in Canada, 1975-1993, Health Canada, Ottawa, 1994: 3-4
2. Guidelines for Economic Evaluation of Pharmaceuticals, Canadian Coordinating Office of Health Technology Assessment, Ottawa, 1994
3. Anis A: Substitution laws, insurance coverage, and generic drug use. Med Care 1994; 32: 240-256
4. Anis A: Pharmaceutical prices with insurance coverage and formularies. Can J Econ 1992; 25: 420-437
5. McIsaac W, Naylor CD, Anderson GM et al: Reflections on a month in the life of the Ontario Drug Benefit Plan. Can Med Assoc J 1994; 150: 473-477
6. Lipton HL, Bird JA: Drug utilization review in ambulatory settings: state of the science and directions for outcomes research. Med Care 1993; 31: 1069-1082
7. Rosholm JU, Hallas J, Gram LF: Outpatient utilization of antidepressants: a prescription database analysis. J Affect Disord 1993; 27: 21-28
8. Pickering T, Gurwitz JH, Zaleznik D et al: The appropriateness of oral fluoroquinolone-prescribing in the long-term care setting. J Am Geriatr Soc 1994; 42: 28-32
9. Vermeulen LC, Matuszewski KA, Ratko TA et al: Evaluation of ondansetron prescribing in US academic medical centers. Arch Intern Med 1994; 154: 1733-1740
10. Tamblyn RM, McLeod PJ, Abrahamowicz M et al: Questionable prescribing for elderly patients in Quebec. Can Med Assoc J 1994; 150: 1801-1809
11. Wennberg JE, Gittelson A: Small area variations in health care delivery. Science 1973; 182: 1102-1109
12. McPhareson K, Wennberg JE, Hovind OB et al: Small-area variations in the use of common surgical procedures: an international comparison of New England, England and Norway. N Engl J Med 1982; 307: 1310-1314
13. Paul-Shaheen P, Clark JD, Williams D: Small-area analysis: a review and analysis of the North American literature. J Health Polit Policy Law 1987; 12: 741-809
14. Blais R: Variations in the use of health care services: Why are more studies needed? Can Med Assoc J 1994; 151: 1701-1703
15. Phelps CE, Parente ST: Priority setting in medical technology and medical practice assessment. Med Care 1990; 28: 703-723
16. Rucher TD: Drug-utilization review moving toward an effective and safe model. In Morgan JP, Kagan DC (eds): Society and Medication. Conflicting Signals for Prescribers and Patients, Lexington Books, Lexington, Mass, 1983: 25-31
17. Folland S, Stano M: Small area variations: a critical review of propositions, methods, and evidence. Med Care Rev 1990; 47: 419-465
18. Wennberg JE: Future directions for small area variations. Med Care 1993; 31 (suppl): YS75-YS80
19. Phelps CE: Diffusion of information in medical care. J Econ Perspect 1992; 6: 23-42
20. Davidson W, Molloy DW, Somers G et al: Relation between physician characteristics and prescribing for elderly people in New Brunswick. Can Med Assoc J 1994; 150: 917-921
21. Davidson W, Molloy DW, Bédard M: Physician characteristics and prescribing for elderly people in New Brunswick: relation to patient outcomes. Can Med Assoc J 1995; 152: 1227-1234
22. Lexchin J: Prescribing by Canadian general practitioners: review of English language literature. Can Fam Physician 1990; 36: 465-470
23. Diehr P, Cain KC, Kreuter W et al: Can small area analysis detect variation in surgery rates? Med Care 1992; 30: 484-502
24. Wennberg JE: Dealing with medical practice variation: a proposal for action. Health Aff 1984; 3: 6-31
25. Shulke DG: A congressional perspective on inappropriate drug therapy and drug utilization review. Clin Pharmacol Ther 1991; 50: 606-611
26. Lexchin J: Doctors and detailers: Therapeutic education or pharmaceutical promotion? Int J Health Serv 1989; 19: 663-679
27. Schwartz RK, Soumerai SB, Avorn J: Physician motivations of nonscientific drug prescribing. Soc Sci Med 1989; 28: 577-582
28. Kralewski J, Wetheimer A, Ratner E: Prescription drug utilization review in the private sector. Health Care Manage Rev 1994; 19: 62-71
29. Erwin WG: The definition of drug utilization review: statement of issues. Clin Pharmacol Ther 1991; 50: 596-599
30. Lipton HL, Bird JA: Drug utilization review: state of the art from an academic perspective. Clin Pharmacol Ther 1991; 50: 616-619
31. Beers MH, Fingold SF, Ouslander JG et al: Characteristics and quality of prescribing by doctors practising in nursing homes. J Am Geriatr Soc 1993; 41: 802-807
32. Kaplan B, Farris K, Kirking DM: Assessing physician choice of nonsteroidal anti-inflammatory drugs in a health maintenance organization. Ann Pharmacother 1993; 27: 1393-1399
33. Jones JK: A view from the drug utilization review management organization sector. Clin Pharmacother 1991; 50: 620-625
34. Wertheimer A, Kralewski J: DUR programs: current trends and future directions. Am Pharm 1993; NS33 (2): 37-42