Gene expression profiling during thymus ontogeny and its association with TCRVβ8.1-Dβ2.1 rearrangements of inbred mouse strains

Molecular and Cellular Biochemistry

Volumn 252, Issue 1-2, 2003, Pages 223-228

  Espanhol, Aline R ^a,b   Macedo, Cláudia ^a   Junta, Cristina M ^a   Cardoso, Renato Sousa ^a   Victorero, Geneviève ^c   Loriod, Beatrice ^c   Nguyen, Catherine ^c   Jordan, Bertrand ^c   Passos, Geraldo A S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^c INSERM   (France)

Author keywords

Cluster analysis; Cytokine; Gene expression profiling; TCRV 8.1; V(D)J recombination

Indexed keywords

BETA ACTIN; CYTOKINE; GAMMA INTERFERON; GENE PRODUCT; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 7; LYMPHOTOXIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; RECOMBINASE; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CLUSTER ANALYSIS; COMPLEX FORMATION; COMPUTER PROGRAM; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FETUS; FETUS DEVELOPMENT; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENE REARRANGEMENT; GENETIC RECOMBINATION; GENETIC SUSCEPTIBILITY; IN VIVO STUDY; INBRED STRAIN; KINETICS; MOLECULAR EVOLUTION; MOUSE; MOUSE STRAIN; NONHUMAN; ONTOGENY; REGULATORY MECHANISM; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRAIN DIFFERENCE; T LYMPHOCYTE; THYMUS;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; GENE EXPRESSION PROFILING; GENE REARRANGEMENT, BETA-CHAIN T-CELL ANTIGEN RECEPTOR; MICE; MICE, INBRED STRAINS; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY; THYMUS GLAND;

ANIMALIA; MAMMALIA; MOUSE MAMMARY TUMOR VIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0141839792     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025556510001     Document Type: Article

References (28)

1. Junta CM, Passos GAS: Emergence of TCRα/β V(D)J recombination and transcription during ontogeny of inbred mouse strains. Mol Cell Biochem 187: 67-72, 1998
2. Macedo C, Junta CM, Passos GAS: Onset off-cell receptor Vβ8.1 and Dβ2.1 V(D)J recombination during thymus development of inbred mouse strains. Immunol Lett 69: 371-373, 1999
3. Muegge K, Vila MP, Durum SK: Interleukin-7: A cofactor for V(D)J rearrangement of the T-cell receptor gene. Science 261: 93-95, 1993
4. Sollof RS, Wang TG, Dempsey D, Jennings SR, Wolcott RM, Chervenak R: Interleukin 7 induces TCR gene rearrangement in adult marrow-resident murine precursor T cells. Mol Immunol 34: 453-462, 1997
5. Candeias S, Muegge K, Durum SK: IL-7 receptor and V(D)J recombination: Trophic vs. mechanistic actions. Immunity 6: 501-508, 1997
6. Haks MC, Oosterwegel MA, Blom B, Spits H, Kruisbeek AM: Cell-fate decisions in early T-cell development regulation by cytokine receptors and pre-TCR. Sem Immunol 11: 23-37, 1999
7. Di Santo JP, Rodewald HR: In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development. Current Opin Immunol 10: 196-207, 1998
8. Laky K, Lefrançois L, von Freeden-Jeffry U, Murray R, Puddington L: The role of IL-7 in thymic and extrathymic development of TCR gamma-delta cells. J Immunol 161: 707-713, 1998
9. Schlissel MS, Durum SD, Muegge K: The interleukin 7 receptor is required for T-cell receptor gamma locus accessibility to V(D)J recombinase. J Exp Med 191: 1045-1050, 2000
10. Weissman IL: Developmental switches in the immune system. Cell 76: 207-218, 1994
11. Mombaerts P, Iacomini J, Johnson RS, Herrup K, Tonegawa S, Papaioannou VE: RAG-1 deficient mice have no mature B and T lymphocytes. Cell 68: 869-877, 1992
12. Hempel WM, Stanhope-Baker P, Mathieu N, Huang F, Schlissel MS, Ferrier P: Enhancer control of V(D)J recombination at the TCR beta locus: Differential effects on DNA cleavage and joining. Genes Dev 12: 2305-2317, 1998
13. Eisen MB, Spellman PT, Brown PO, Botstein D: Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 95: 14863-14868, 1998
14. Eisen M: Gene cluster treeview. Stanford University (http.//genome-www.stanford.edu/serum), 2001
15. Rugh R: The Mouse: Its Reproduction and Development. Burgess, Minneapolis, 1968
16. Rothenberg EV, Telfer JC, Anderson MK: Transcriptional regulation of lymphocyte lineage commitment. BioEssays 21: 726-742, 1999
17. Wilson A, Held W, MacDonald HR: Two waves of recombinase expression in developing thymocytes. J Exp Med 179: 1335-1360, 1994
18. Turka LA, Schatz DG, Clettinger MA, Chun JJM, Gorka C, Lee K, Mc Cormack WT, Thompson CB: Thymocyte expression of RAG-1 and RAG-2: Termination by T-cell receptor cross-linking. Science 253: 778-781, 1991
19. Mallick CA, Dudley EC, Viney JL, Owen MJ, Hayday AC: Rearrangement and diversity of T-cell receptor beta chain genes in thymocytes: A critical role for the beta chain. Cell 73: 513-519, 1993
20. Godfrey DI, Kennedy J, Mombaerts P, Tonegawa S, Zlotnik A: Onset of TCRβ gene rearrangement and role of TCRβ expression during CD3-, CD4-, CD8- thymocyte differentiation. J Immunol 152: 4783-4791, 1994
21. Chung S, Strominger JL: Regulation of T-cell antigen receptor (TCR) α-chain expression by TCRβ chain transcripts. Proc Natl Acad Sci USA 92: 3712-3716, 1995
22. Guidos CJ, Williams CJ, Wu GE, Paige CJ, Danska JS: Development of CD4+ CD8+ thymocytes in RAG-deficient mice through a T-cell receptor β chain-independent pathway. J Exp Med 181: 1187-1195, 1995
23. Robey E, Fowlkes BJ: Selective events in T-cell development. Ann Rev Immunol 12: 675-705, 1994
24. Acha-Orbea H, Shakhov AN, Scarpellino L, Kolb E, Muller V, Vessazshaw A, Fuchs R, Blochlinger K, Rollini P, Billotte J, Sarafidou M, MacDonald HR, H. Diggelmann H: Clonal deletion of V-beta 14-bearing T-cells in mice transgenic for mammary tumour virus. Nature 350: 207-211, 1991
25. Barnett A, Mustafa F, Wrona TJ, Lozano M, Dudley JP: Expression of mouse mammary tumor virus superantigen mRNA in the thymus correlates with kinetics of self-reactive T-cell loss. J Virology 73: 6634-6645, 1999
26. Montgomery RA, Dallman MJ: Analysis of cytokine gene expression during fetal thymic ontogeny using polymerase chain reaction. J Immunol 147: 554-560, 1991
27. Hikida M, Mori M, Kawabata T, Takai T, Ohmori H: Characterization of B-cells expressing recombination activating genes in germinal centers of immunized mouse lymph nodes. J Immunol 158: 2509-2512, 1997
28. Le Bon A, Desaymard C, Papiernik M: Neonatal impaired response to viral superantigen encoded by MMTV(SW) and Mtv-7. Int Immunol 7: 1897-1903, 1995