The sodium channel blocker RS100642 reverses down-regulation of the sodium channel α-subunit Nav 1.1 expression caused by transient ischemic brain injury in rats

Neurotoxicity Research

Volumn 5, Issue 4, 2003, Pages 245-253

  Yao, C ^a   Williams, A J ^a   Lu, X C M ^a   Price, R A ^a   Cunningham, B S ^a   Berti, R ^a   Tortella, F C ^a   Dave, Jit R ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

Gene expression; Ischemia; Mexiletine; Middle cerebral artery occlusion; RS100642; Sodium channel blockers; Sodium channels

Indexed keywords

DRUG DERIVATIVE; MEXILETINE; NERVE PROTEIN; NEUROPROTECTIVE AGENT; RS100642; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL, VOLTAGE GATED, TYPE I, ALPHA PROTEIN; SODIUM CHANNEL, VOLTAGE GATED, TYPE II, ALPHA 1; SODIUM CHANNEL, VOLTAGE-GATED, TYPE I, ALPHA PROTEIN; SODIUM CHANNEL, VOLTAGE-GATED, TYPE II, ALPHA 1;

ANIMAL; ARTICLE; CEREBRAL ARTERY DISEASE; DOWN REGULATION; DRUG EFFECT; GENE EXPRESSION; GENETICS; MALE; PATHOPHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; DOWN-REGULATION; GENE EXPRESSION; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MALE; MEXILETINE; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 0141835035     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03033382     Document Type: Article

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