Effects of ethanol on gut-associated lymphoid tissues in a model of bacterial translocation: A possible role of apoptosis

Alcohol

Volumn 30, Issue 3, 2003, Pages 183-191

  Souza, Heitor S P ^a,b   Elia, Celeste C S ^a   Braulio, Valeria B ^a   Côrtes, Mauro Q ^a   Furtado, Valeria C S ^a   Garrofé, Henrique C ^a   Martinusso, Cesônia A ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b NONE   (Brazil)

Author keywords

Apoptosis; Bacterial translocation; Cell proliferation; Ethanol; Mucosal immunity

Indexed keywords

ALCOHOL; BIOTIN; CYCLINE; DNA NUCLEOTIDYLEXOTRANSFERASE; IMMUNOGLOBULIN A; TETRACYCLINE; URIDINE DIPHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL TRANSLOCATION; CALORIC INTAKE; COLON; CONTROLLED STUDY; DIET; DUODENUM; ESCHERICHIA COLI; ILEUM; IMMUNE FUNCTION TEST; IMMUNITY; IMMUNOHISTOCHEMISTRY; INTESTINE LYMPHATIC TISSUE; INTESTINE MUCOSA; JEJUNUM; KIDNEY; LAMINA PROPRIA; LIVER; MACROPHAGE; MALE; MESENTERY LYMPH NODE; NICK END LABELING; NONHUMAN; RAT; RAT STRAIN; SMALL INTESTINE; SPLEEN; STOMACH INTUBATION; T LYMPHOCYTE;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; RATTUS NORVEGICUS;

EID: 0141790165     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(03)00134-4     Document Type: Article

References (41)

1. Bardou M., Montembault S., Giraud V., Balian A., Borotto E., Houdayer C., Capron F., Chaput J.-C., Naveau S. Excessive alcohol consumption favours high risk polyp or colorectal cancer occurrence among patients with adenomas: a case control study. Gut. 50:2002;38-42.
2. Braulio V.B., De Queiroz Cortes M., Borges-Neto A.A., Bastos M.A., Cruz M.S. Jr., Fracalanza S.E. Inhibition of bacterial translocation by chronic ethanol consumption in the rat. APMIS. 109:2001;809-815.
3. Choudhry M.A., Fazal N., Goto M., Gamelli R.L., Sayeed M.M. Gut-associated lymphoid T cell suppression enhances bacterial translocation in alcohol and burn injury. Am J Physiol Gastrointest Liver Physiol. 282:2002;G937-G947.
4. Choudhry M.A., Messingham K.A.N., Namak S., Colantoni A., Fontanilla C.V., Duffner L.A., Sayeed M.M., Kovacs E.J. Ethanol exacerbates T cell dysfunction after thermal injury. Alcohol. 21:2000;239-243.
5. Dehne N.E., Mendenhall C.L., Roselle G.A., Grossman C.J. Cell-mediated immune responses associated with short-term alcohol intake: time course and dose dependency. Alcohol Clin Exp Res. 13:1989;201-205.
6. Deitch E.A., Bridges W.M., Ma J.W., Ma L., Berg R.D., Specian R.D. Obstructed intestine as a reservoir for systemic infection. Am J Surg. 159:1990a;394-401.
7. Deitch E.A., Ma W.J., Ma L., Berg R.D., Specian R.D. Protein malnutrition predisposes to inflammatory-induced gut-origin septic states. Ann Surg. 211:1990b;560-567.
8. Deitch E.A., Xu D.Z., Qi L., Specian R.D., Berg R.D. Protein malnutrition alone and in combination with endotoxin impairs systemic and gut-associated immunity. JPEN J Parenter Enteral Nutr. 16:1992;25-31.
9. Dunne F.J. Alcohol and the immune system. BMJ. 298:1989;543-544.
10. Fryer J., Grant D., Jiang J., Metrakos P., Ozcay N., Ford C., Garcia B., Behme R., Zhong R. Influence of macrophage depletion on bacterial translocation and rejection in small bowel transplantation. Transplantation. 62:1996;553-559.
11. Grassmé H., Kirschnek S., Riethmueller J., Riehle A., von Kürthy G., Lang F., Weller M., Gulbins E. CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa. Science. 290:2000;527-530.
12. Grossman C.J., Mendenhall C.L., Roselle G.A. Alcohol and immune regulation. I. In vivo effects of ethanol on concanavalin A sensitive thymic lymphocyte function. Int J Immunopharmacol. 10:1988;187-195.
13. Hall P.A., Coates P.J., Ansari B., Hopwood D. Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci. 107:1994;3569-3577.
14. Homann N., Karkkainen P., Koivisto T., Nosova T., Jokelainen K., Salaspuro M. Effects of acetaldehyde on cell regeneration and differentiation of the upper gastrointestinal tract mucosa. J Natl Cancer Inst. 89:1997;1692-1697.
15. + T lymphocytes in humans. J Immunol. 166:2001;6952-6963.
16. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council. Guide for the Care and Use of Laboratory Animals. 1996;National Academy Press, Washington, DC.
17. Jayasinghe R., Gianutsos G., Hubbard A.K. Ethanol-induced suppression of cell-mediated immunity in the mouse. Alcohol Clin Exp Res. 16:1992;331-335.
18. Jerrells T.R., Smith W., Eckardt M.J. Murine model of ethanol-induced immunosuppression. Alcohol Clin Exp Res. 14:1990;546-550.
19. Koh I.H., Silva R.M. Novel in vitro small intestinal graft model for study of bacterial translocation in the rat. Transplant Proc. 28:1996;2667-2668.
20. Lopez M.C., Huang D.S., Borgs P., Wang Y., Watson R.R. Modification of lymphocyte subsets in the intestinal-associated immune system and thymus by chronic ethanol consumption. Alcohol Clin Exp Res. 18:1994;8-11.
21. MacFie J., O'Boyle C., Mitchell C.J., Buckley P.M., Johnstone D., Sudworth P. Gut origin of sepsis: a prospective study investigating associations between bacterial translocation, gastric microflora, and septic morbidity. Gut. 45:1999;223-228.
22. MacGregor R.R. Alcohol and immune defense. JAMA. 256:1986;1474-1479.
23. Mason C.M., Dobard E., Kolls J., Nelson S. Effect of alcohol on bacterial translocation in rats. Alcohol Clin Exp Res. 22:1998;1640-1645.
24. Meadows G.G., Blank S.E., Duncan D.D. Influence of ethanol consumption on natural killer cell activity in mice. Alcohol Clin Exp Res. 13:1989;476-479.
25. Messingham K.A.N., Fontanilla C.V., Colantoni A., Duffner L.A., Kovacs E.J. Cellular immunity after ethanol exposure and burn injury: dose and time dependence. Alcohol. 22:2000;35-44.
26. Mora E.M., Cardona M.A., Simmons R.L. Enteric bacteria and ingested inert particles translocate to intraperitoneal prosthetic materials. Arch Surg. 126:1991;157-163.
27. Mufti S.I., Prabhala R., Moriguchi S., Sipes I.G., Watson R.R. Functional and numerical alterations induced by ethanol in the cellular immune system. Immunopharmacology. 15:1988;85-93.
28. Napolitano L.M., Koruda M.J., Zimmerman K., McCowan K., Chang J., Meyer A.A. Chronic ethanol intake and burn injury: evidence for synergistic alteration in gut and immune integrity. J Trauma. 38:1995;198-207.
29. Neuman M.G., Shear N.H., Cameron R.G., Katz G., Tiribelli C. Ethanol-induced apoptosis in vitro. Clin Biochem. 32:1999;547-555.
30. Noda T., Iwakiri R., Fujimoto K., Matsuo S., Aw T.Y. Programmed cell death induced by ischemia-reperfusion in rat intestinal mucosa. Am J Physiol Gastrointest Liver Physiol. 274:1998;G270-G276.
31. Potten C.S., Booth C. The role of radiation-induced and spontaneous apoptosis in the homeostasis of the gastrointestinal epithelium: a brief review. Comp Biochem Physiol B Biochem Mol Biol. 118:1997;473-478.
32. Que F.G., Gores G.J. Cell death by apoptosis: basic concepts and disease relevance for the gastroenterologist. Gastroenterology. 110:1996;1238-1243.
33. Reeves P.G., Nielsen F.H., Fahey G.C. Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 123:1993;1939-1951.
34. Roselle G.A., Mendenhall C.L. Ethanol-induced alterations in lymphocyte function in the guinea pig. Alcohol Clin Exp Res. 8:1984;62-67.
35. Seitz H.K., Simanowski U.A., Garzon F.T., Rideout J.M., Peters T.J., Koch A., Berger M.R., Einecke H., Maiwald M. Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the rat. Gastroenterology. 98:1990;406-413.
36. Shellito J.E., Olariu R. Alcohol decreases T-lymphocyte migration into lung tissue in response to Pneumocystis carinii and depletes T-lymphocyte numbers in the spleens of mice. Alcohol Clin Exp Res. 22:1998;658-663.
37. Sibley D., Jerrells T.R. Alcohol consumption by C57BL/6 mice is associated with depletion of lymphoid cells from the gut-associated lymphoid tissues and altered resistance to oral infections with Salmonella typhimurium. J Infect Dis. 182:2000;482-489.
38. Simanowski U.A., Homann N., Knühl M., Arce L., Waldherr R., Conradt C., Bosch F.X., Seitz H.K. Increased rectal cell proliferation following alcohol abuse. Gut. 49:2001;418-422.
39. Thornberry N.A., Lazebnik Y. Caspases: enemies within. Science. 281:1998;1312-1316.
40. Watzl B., Watson R.R. Role of alcohol abuse in nutritional immunosuppression. J Nutr. 122:(3 Suppl):1992;733-737.
41. Welsh F.K.S., Farmery S.M., MacLennan K., Sheridan M.B., Barclay G.R., Guillou P.J., Reynolds J.V. Gut barrier function in malnourished patients. Gut. 42:1998;396-401.