Endothelin receptor blockade has an oxygen-saving effect in Dahl salt-sensitive rats with heart failure

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 285, Issue 4 54-4, 2003, Pages

  Noguchi, Teruo ^a   Chen, Zengyi ^a   Bell, Stephen P ^a   Nyland, Lori ^a   LeWinter, Martin M ^a,b  

^a UNIVERSITY OF VERMONT   (United States)

^b FLETCHER ALLEN HEALTH CARE   (United States)

Author keywords

Oxygen consumption

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; OXYGEN; PROTON; SODIUM CHLORIDE; SODIUM ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENERGY METABOLISM; HEART FAILURE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE OXYGEN CONSUMPTION; HEART VENTRICLE PRESSURE; HEART VOLUME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; RAT; RAT STRAIN; RECEPTOR BLOCKING;

EID: 0141788763     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00731.2002     Document Type: Article

References (38)

1. Belloni AS, Rossi GP, Andreis PG, Neri G, Albertin G, Pessina AC, and Nussdorfer GG. Endothelin adrenocortical secretagogue effect is mediated by the B receptor in rats. Hypertension 27: 1153-1159, 1996.
2. Burkhoff D, Sugiura S, Yue DT, and Sagawa K. Contractility-dependent curvilinearity of end-systolic pressure-volume relations. Am J Physiol Heart Circ Physiol 252: H1218-H1227, 1987.
3. Clozel M, Gray GA, Breu V, Loffier BM, and Osterwalder R. The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo. Biochem Biophys Res Commun 186: 867-873, 1992.
4. Dahl LK, Knudsen KD, Heine MA, and Leitl GJ. Effects of chronic excess salt ingestion. Modification of experimental hypertension in the rat by variations in the diet. Circ Res 22: 11-18, 1968.
5. Dijkman MA, Heslinga JW, Sipkema P, and Westerhof N. Perfusion-induced changes in cardiac contractility depend on capillary perfusion. Am J Physiol Heart Circ Physiol 274: H405-H410, 1998.
6. Gibbs CL, Wendt IR, Kotsanas G, and Young IR. Mechanical, energetic, and biochemical changes in long-term volume overload of rabbit heart. Am J Physiol Heart Circ Physiol 262: H819-H827, 1992.
7. Gilbert JC and Glantz SA. Determinants of left ventricular filling and of the diastolic pressure- volume relation. Circ Res 64: 827-852, 1989.
8. 2 consumption and systolic pressure-volume area or force-time integral. Circ Res 66: 999-1011, 1990.
9. Goto Y, Slinker BK, and LeWinter MM. Effect of coronary hyperemia on Emax and oxygen consumption in blood-perfused rabbit hearts. Energetic consequences of Gregg's phenomenon. Circ Res 68: 482-492, 1991.
10. Hirata Y, Emori T, Eguchi S, Kanno K, Imai T, Ohta K, and Marumo F. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J Clin Invest 91: 1367-1373, 1993.
11. Ingwall JS. Is cardiac failure a consequence of decreased energy reserve? Circulation 87, Suppl VII: VII-58-VII-62, 1993.
12. Inoko M, Kihara Y, Morii I, Fujiwara H, and Sasayama S. Transition from compensatory hypertrophy to dilated, failing left ventricles in Dahl salt-sensitive rats. Am J Physiol Heart Circ Physiol 267: H2471-H2482, 1994.
13. + exchange is impaired in cardiac hypertrophy. J Clin Invest 99: 125-135, 1997.
14. Iwanaga Y, Kihara Y, Hasegawa K, Inagaki K, Yoneda T, Kaburagi S, Araki M, and Sasayama S. Cardiac endothelin-1 plays a critical role in the functional deterioration of left ventricles during the transition from compensatory hypertrophy to congestive heart failure in salt-sensitive hypertensive rats. Circulation 98: 2065-2073, 1998.
15. Kameyama T, Chen Z, Bell SP, VanBuren P, Maughan D, and LeWinter MM. Mechanoenergetic alterations during the transition from cardiac hypertrophy to failure in Dahl salt-sensitive rats. Circulation 98: 2919-2929, 1998.
16. Kleyman TR and Cragoe EJ Jr. Amiloride and its analogs as tools in the study of ion transport. J Membr Biol 105: 1-21, 1988.
17. Kobayashi T, Miyauchi T, Sakai S, Kobayashi M, Yamaguchi I, Goto K, and Sugishita Y. Expression of endothelin-1, ETA and ETB receptors, and ECE and distribution of endothelin-1 in failing rat heart. Am J Physiol Heart Circ Physiol 276: H1197-H1206, 1999.
18. + exchanger. Circ Res 68: 269-279, 1991.
19. MacCarthy PA, Grocott-Mason R, Prendergast BD, and Shah AM. Contrasting inotropic effects of endogenous endothelin in the normal and failing human heart: studies with an intracoronary ET(A) receptor antagonist. Circulation 101: 142-147, 2000.
20. McClellan G, Weisberg A, Rose D, and Winegrad S. Endothelial cell storage and release of endothelin as a cardioregulatory mechanism. Circ Res 75: 85-96, 1994.
21. McCurdy D, Palmer BM, Maughan DW, and LeWinter MM. Myocardial cross-bridge kinetics in transition to failure in Dahl salt-sensitive rats. Am J Physiol Heart Circ Physiol 281: H1390-H1396, 2001.
22. Moravec CS, Reynolds EE, Stewart RW, and Bond M. Endothelin is a positive inotropic agent in human and rat heart in vitro. Biochem Biophys Res Commun 159: 14-18, 1989.
23. Mulder P, Boujedaini H, Richard V, Derumeaux G, Henry JP, Renet S, Wessale J, Opgenorth T, and Thuillez C. Selective endothelin-A versus combined endothelin-A/endothelin-B receptor blockade in rat chronic heart failure. Circulation 102: 491-493, 2000.
24. 2 consumption and increases contractile efficiency in rats. Am J Physiol Heart Circ Physiol 281: H2191-H2197, 2001.
25. Noguchi T, Kihara Y, Begin KJ, Gorga JA, Palmiter KA, LeWinter MM, and VanBuren P. Altered myocardial thin filament composition and function in the failing Dahl salt sensitive rat heart. Circulation 107: 630-635, 2003.
26. Peter MG and Davenport AP. Characterization of the endothelin receptor selective agonist, BQ3020 and antagonists BQ123, FR139317, BQ788, 50235, Ro462005 and bosentan in the heart. Br J Pharmacol 117: 455-462, 1996.
27. Pieske B, Beyermann B, Breu V, Loffler BM, Schlotthauer K, Maier LS, Schmidt-Schweda S, Just H, and Hasenfuss G. Functional effects of endothelin and regulation of endothelin receptors in isolated human nonfailing and failing myocardium. Circulation 99: 1802-1809, 1999.
28. Poderoso JJ, Peralta JG, Lisdero CL, Carreras MC, Radisic M, Schopfer F, Cadenas E, and Boveris A. Nitric oxide regulates oxygen uptake and hydrogen peroxide release by the isolated beating rat heart. Am J Physiol Cell Physiol 274: C112-C119, 1998.
29. Sakai S, Miyauchi T, Kobayashi M, Yamaguchi I, Goto K, and Sugishita Y. Inhibition of myocardial endothelin pathway improves long-term survival in heart failure. Nature 384: 353-355, 1996.
30. Sakai S, Miyauchi T, Sakurai T, Kasuya Y, Ihara M, Yamaguchi I, Goto K, and Sugishita Y. Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Marked increase in endothelin-1 production in the failing heart. Circulation 93: 1214-1222, 1996.
31. Serneri GG, Cecioni I, Vanni S, Paniccia R, Bandinelli B, Vetere A, Janming X, Bertolozzi I, Boddi M, Lisi GF, Sani G, and Modesti PA. Selective upregulation of cardiac endothelin system in patients with ischemic but not idiopathic dilated cardiomyopathy: endothelin-1 system in the human failing heart. Circ Res 86: 377-385, 2000.
32. Shimoyama H, Sabbah HN, Borzak S, Tanimura M, Shevlyagin S, Scicli G, and Goldstein S. Short-term hemodynamic effects of endothelin receptor blockade in dogs with chronic heart failure. Circulation 94: 779-784, 1996.
33. Spinale FG, Walker JD, Mukherjee R, Iannini JP, Keever AT, and Gallagher KP. Concomitant endothelin receptor subtype-A blockade during the progression of pacing-induced congestive heart failure in rabbits. Beneficial effects on left ventricular and myocyte function. Circulation 95: 1918-1929, 1997.
34. Suga H. Ventricular energetics. Physiol Rev 70: 247-277, 1990.
35. Takeuchi Y, Kihara Y, Inagaki K, Yoneda T, and Sasayama S. Endothelin-1 has a unique oxygen-saving effect by increasing contractile efficiency in the isolated rat heart. Circulation 103: 1557-1563, 2001.
36. Thomas PB, Liu EC, Webb ML, Mukherjee R, Hebbar L, and Spinale FG. Exogenous effects and endogenous production of endothelin in cardiac myocytes: potential significance in heart failure. Am J Physiol Heart Circ Physiol 271: H2629-H2637, 1996.
37. Verhaar MC, Strachan FE, Newby DE, Cruden NL, Koomans HA, Rabelink TJ, and Webb DJ. Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade. Circulation 97: 752-756, 1998.
38. Yoneda T, Kihara Y, Ohkusa T, Iwanaga Y, Inagaki K, Takeuchi Y, Hayashida W, Ueyama T, Hisamatsu Y, Fujita M, Hatac S, Matsuzaki M, and Sasayama S. Calcium handling and sarcoplasmic-reticular protein functions during heart-failure transition in ventricular myocardium from rats with hypertension. Life Sci 70: 143-157, 2001.