Short-term hemodynamic effects of endothelin receptor blockade in dogs with chronic heart failure

Circulation

Volumn 94, Issue 4, 1996, Pages 779-784

  Shimoyama, Hisashi ^a   Sabbah, Hani N ^a,b   Borzak, Steven ^a   Tanimura, Mitsuhiro ^a   Shevlyagin, Serguei ^a   Scicli, Gloria ^a   Goldstein, Sidney ^a  

^a HENRY FORD HEART AND VASCULAR INSTITUTE   (United States)

^b HENRY FORD HOSPITAL   (United States)

Author keywords

endothelin; heart failure; receptors

Indexed keywords

BOSENTAN; ENDOTHELIN RECEPTOR ANTAGONIST;

ANIMAL MODEL; AORTA PRESSURE; ARTICLE; CONTROLLED STUDY; DOG; ECHOCARDIOGRAPHY; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART OUTPUT; HEART RATE; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; SYSTEMIC VASCULAR RESISTANCE;

EID: 0029738660     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.94.4.779     Document Type: Article

References (47)

1. Masaki T, Kimura S, Yanagisawa M, Goto K. Molecular and cellular mechanism of endothelin regulation: implication for vascular function. Circulation. 1991;84:1457-1467.
2. Inoue A, Yanagisawa M, Kimura S, Kasuya Y, Miyauchi T, Goto K, Masaki T. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA. 1989;86:2863-2867.
3. B receptors mediate contraction to endothelin-1 in human bloodvessels. Circulation. 1994;89:1203-1208.
4. O'Brien RF, Robbins RJ, McMurtry IF. Endothelial cells in culture produce a vasoconstrictor substance. J Cell Physiol. 1987;132:263-270.
5. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
6. Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature. 1990;348:730-732.
7. Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kimura S, Goto K, Masaki M. Cloning a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature. 1990;348:732-735.
8. Ando K, Hirata Y, Shichiri M, Emori T, Muramo F. Presence of immunoreactive endothelin in human plasma. FEBS Lett. 1989;245:164-166.
9. Cody RJ, Haas GJ, Binkley PF, Capers Q, Kelly R. Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation. 1992;85:504-509.
10. Rodeheffer RJ, Lerman A, Heublein DM, Burnett JC Jr. Increased plasma concentration of endothelin in congestive heart failure in humans. Mayo Clin Proc. 1992;67:719-724.
11. Cavero PG, Miller WL, Heublein DM, Margulies KB, Burnett JC Jr. Endothelin in experimental congestive heart failure in the anesthetized dog. Am J Physiol. 1990;259:F312-F317.
12. Sabbah HN, Kono T, Scicli AG, Scicli G, Stein PD, Carretero OA. Endothelin plasma concentration is increased in dogs with chronic heart failure. Circulation. 1991;84(suppl II):II-470. Abstract.
13. Teerlink JR, Loffler BM, Hess P, Maire JP, Clozel M, Clozel JP. Role of endothelin in maintenance of blood pressure in conscious rats with chronic heart failure: acute effects of the endothelin receptor antagonist Ro 40-0203 (bosentan). Circulation. 1994;90:2510-2518.
14. Cernacek P, Stewart DJ. Immunoreactive endothelin in human plasma: marked elevations in patients with cardiogenic shock. Biochem Biophys Res Commun. 1989;161:562-567.
15. Qiu S, Theroux P, Marcil M, Solymoss BC. Plasma endothelin-1 levels in stable and unstable angina. Cardiology. 1993;82:12-19.
16. Miyauchi T, Yanagisawa M, Tomizawa T, Sigishita Y, Suzuki N, Fujino M, Ajisaka R, Goto K, Masaki T. Increased plasma concentrations of endothelin-1 and big endothelin-1 in acute myocardial infarction. Lancet. 1989;2:53-54.
17. Stewart DJ, Kubac G, Costello KB, Cernacek P. Increased plasma endothelin-1 in the early hours of acute myocardial infarction. J Am Coll Cardiol. 1991;18:38-43.
18. Margulies KB, Hildebrand FL Jr, Lerman A, Perrella MA, Burnett JC Jr. Increased endothelin in experimental heart failure. Circulation. 1990;82:2226-2230.
19. Underwood RD, Aarhus LL, Heublein DM, Burnett JC Jr. Endothelin in thoracic inferior vena caval constriction model of heart failure. Am J Physiol. 1992;263:H951-H955.
20. Sabbah HN, Stein PD, Kono T, Gheorghiade M, Le vine TB, Jafri S, Hawkins ET, Goldstein S. A canine model of chronic heart failure produced by multiple sequential intracoronary microembolizations. Am J Physiol. 1991;260:H1379-H1384.
21. Sabbah HN, Shimoyama H, Kono T, Gupta RC, Sharov VG, Scicli G, Levine TB, Goldstein S. Effects of long-term monotherapy with enalapril. metoprolol, and digoxin on the progression of left ventricular dysfunction and dilation in dogs with reduced ejection fraction. Circulation. 1994;89:2852-2859.
22. Weiss JL, Frederiksen JW, Weisfeldt ML. Hemodynamic determinants of the time-course of fall in canine left ventricular pressure. J Clin Invest. 1976;58:751-760.
23. Kono T, Sabbah HN, Rosman H, Alam M, Jafri S, Stein PD, Goldstein S. Mechanism of functional mitral regurgitation during acute myocardial ischemia. J Am Coll Curdiol. 1992;19:1101-1105.
24. Teerlink JR, Carteaux J-P, Sprecher URS, Loffler B-M, Clozel M, Clozel J-P. Role of endogenous endothelin in normal hemodynamic status of anesthetized dogs. Am J Physiol. 1995;268:H432-H440.
25. Thomas JA, Marks BH. Plasma norepinephrine in congestive heart failure. Am J Cardiol. 1978;41:233-243.
26. Levine TB, Francis GS, Goldsmith SR, Simon AB, Cohn JN. Activity of the sympathetic nervous system and renin-angiotensin system assessed by plasma hormone levels and their relation to hemodynamic abnormalities in congestive heart failure. Am J Cardiol. 1982;49:1659-1666.
27. Goldsmith SR, Francis GS, Cowley AW Jr, Levine TB, Cohn JN. Increased plasma arginine vasopressin in patients with congestive heart failure. J Am Coll Cardiol. 1983;1:1385-1390.
28. Masaki T, Yanagisawa M, Goto K, Kimura S. Role of endothelin in mechanisms of local blood pressure control. J Hypertens. 1990;8(suppl 7):S107-S112.
29. Yoshizumi M, Kurihara H, Sugiyama T, Takaku F, Yanagisawa M, Masaki T, Yazaki Y. Hemodynamic shear stress stimulates endothelin production by cultured endothelial cells. Biochem Biophys Res Commun. 1989;161:859-864.
30. Shichiri M, Hirata Y, Ando K, Kanno K, Emori T, Ohta K, Marumo F. Postural change and volume expansion affect plasma endothelin levels. JAMA, 1990;263:661. Letter.
31. Rubanyi GM. Potential physiological and pathological significance of endothelins. Drugs Future. 1992;17:915-936.
32. Sokolovsky M. Endothelins and sarafotoxins: physiological regulation, receptor subtypes and transmembrane signaling. Pharmacol Ther. 1992;54:129-149.
33. Harrison VJ, Randriantsoa A, Schoeffter P. Heterogeneity of endothelin-sarafotoxin receptors mediating contraction of pig coronary arteries. Br J Pharmacol. 1992;105:511-513.
34. B receptors in canine coronary arteries. Circ Res. 1994;74:105-114.
35. Douglas SA, Louden C, Vickery-Clark LM, Storer BL, Hart T, Feuerstein GZ, Elliott JD, Ohlstein EH. A role for endogenous endothelin-1 in neointimal formation after rat carotid artery balloon angioplasty: protective effects of the novel nonpeptide endothelin receptor antagonist SB 209670. Circ Res. 1994;75:190-197.
36. Grover GJ, Dzwonczyk S, Parham CS. The endothelin-1 receptor antagonist BQ-123 reduces infarct size in a canine model of coronary occlusion and reperfusion. Cardiovasc Res. 1991;27:1613-1618.
37. Velasco CE, Yanagisawa M. Endothelins protect the ischemic myocardium. J Am Coll Cardiol. 1994;23:30A. Abstract.
38. A receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload. Circulation. 1994;89:2198-2203.
39. Ishikawa T, Yanagisawa M, Kanura S, Goto K, Masaki T. Positive inotropic action of a novel vasoconstrictor peptide endothelin on guinea pig atria. Am J Physiol. 1988;255:H970-H973.
40. Li K, Stewart DJ, Rouleau JL. Myocardial contractile actions of endothelin-1 in rat and rabbit papillary muscle: role of endocardial endothelium. Circ Res. 1991;69:301-312.
41. McClellan G, Weisberg A, Winegrad S. Endothelin regulation of cardiac contractility in absence of added endothelin. Am J Physiol. 1995;268:H1621-H1627.
42. Sabbah HN, Levine TB, Gheorghiade M, Kono T, Goldstein S. Hemodynamic response of a canine model of chronic heart failure to intravenous dobutamine, nitroprusside, enalaprilat and digoxin. Cardiovasc Drugs Ther. 1993;7:349-356.
43. Packer M, Meller J, Medina N, Yushak M, Gorlin R. Determinants of drug response in severe chronic heart failure, I: activation of vasoconstrictor forces during vasodilator therapy. Circulation. 1981;64:506-514.
44. Sabbah HN, Kono T, Stein PD, Mancini GBJ, Goldstein S. Left ventricular shape changes during the course of evolving heart failure. Am J Physiol 1992;263:H266-H270.
45. Sabbah HN, Goldberg AD, Schoels W, Kono T, Brachmann J, Goldstein S. Spontaneous and inducible ventricular arrhythmias in a canine model of chronic heart failure: relation to hemodynamics and sympathoadrenergic activation. Eur Heart J. 1992;13:1562-1572.
46. Sabbah HN, Kono T, Rosman H, Jafri S, Stein PD, Goldstein S. Left ventricular shape: a factor in the etiology of functional mitral regurgitation in heart failure. Am Heart J. 1992;123:961-966.
47. Gengo PJ, Sabbah HN, Steffen RP, Sharpe JK, Kono T, Stein PD, Goldstein S. Myocardial beta-adrenoceptor and voltage sensitive calcium channel changes in a canine model of chronic heart failure. J Mol Cell Cardiol. 1992;24:1361-1369.