Vascular effects of sildenafil in hypertensive cardiac transplant recipients

American Journal of Hypertension

Volumn 16, Issue 10, 2003, Pages 874-877

  Schofield, Richard S ^a,b,d   Edwards, David G ^c   Schuler, Brian T ^a   Estrada, Juan ^a   Aranda Jr , Juan M ^a   Pauly, Daniel F ^a   Hill, James A ^a   Aggarwal, Rahul ^a   Nichols, Wilmer W ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEW HAMPSHIRE   (United States)

^d Box 100277 ^*  (United States)

Author keywords

Arterial compliance; Heart transplantation; Hypertension; Sildenafil

Indexed keywords

ANTIHYPERTENSIVE AGENT; IMMUNOSUPPRESSIVE AGENT; SILDENAFIL;

ADULT; AORTA PRESSURE; ARTERY COMPLIANCE; ARTICLE; BLOOD VESSEL REACTIVITY; BRACHIAL ARTERY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG TOLERABILITY; GRAFT REJECTION; HEART AFTERLOAD; HEART GRAFT; HEART INDEX; HEART LEFT VENTRICLE COMPLIANCE; HEART RATE; HEART STRESS; HUMAN; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; PRIORITY JOURNAL; PULSE PRESSURE; RECIPIENT; SYSTOLIC BLOOD PRESSURE;

EID: 0141786713     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0895-7061(03)01006-9     Document Type: Article

References (18)

1. Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA: Oral sildenafil in the treatment of erectile dysfunction (Erratum, N Engl J Med 1998;339:59). N Engl J Med 1998;338:1397-1404.
2. Jackson G, Benjamin N, Jackson N, Allen MJ: Effects of sildenafil citrate on human hemodynamics. Am J Cardiol 1999;83:13C-20C.
3. Herrmann HC, Chang G, Klugherz BD, Mahoney PD: Hemodynamic effects of sildenafil in men with severe coronary artery disease. N Engl J Med 2000;342:1622-1626.
4. Katz SD, Balidemaj K, Homma S, Wu H, Wang J, Maybaum S: Acute type 5 phosphodiesterase inhibition with sildenafil enhances flow-mediated vasodilation in patients with chronic heart failure. J Am Coll Cardiol 2000;36:845-851.
5. Zusman RM, Prisant LM, Brown MJ: Effect of sildenafil citrate on blood pressure and heart rate in men with erectile dysfunction taking concomitant antihypertensive medication. Sildenafil Study Group. J Hypertens 2000;18:1865-1869.
6. Mahmud A, Hennessy M, Feely J: Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men. J Hum Hypertens 2001;15:707-713.
7. Braith RW, Mills RM, Wilcox CS, Davis GL, Wood CE: Breakdown of blood pressure and body fluid homeostasis in heart transplant recipients. J Am Coll Cardiol 1996;27:375-383.
8. Wilkinson IB, Fuchs SA, Jansen IM, Spratt JC, Murray GD, Cockcroft JR, Webb DJ: Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis. J Hypertens 1998;16:2079-2084.
9. Pauca AL, O'Rourke MF, Kon ND: Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform. Hypertension 2001;38:932-937.
10. Nichols WW, Edwards DG: Arterial elastance and wave reflection augmentation of systolic blood pressure: deleterious effects and implications for therapy. J Cardiovasc Pharmacol Ther 2001;6:5-21.
11. Sarnoff SJ, Braunwald E, Welch GH, Case RB, Stainsby WN, Macruz R: Hemodynamic determinants of oxygen consumption of the heart with special reference to the tension-time index. Am J Physiol 1958;192:148-156.
12. Schofield RS, Schuler BT, Edwards DG, Aranda JM Jr, Hill JA, Nichols WW: Amplitude and timing of central aortic pressure wave reflections in heart transplant recipients. Am J Hypertens 2002;15:809-815.
13. Nichols WW, O'Rourke MF: McDonald's Blood Flow in Arteries: Theoretic, Experimental and Clinical Principles, 4th ed. Edward Arnold, London, 1998.
14. Mahmud A, Feely J: Reduction in arterial stiffness with angiotensin II antagonist is comparable with and additive to ACE inhibition. Am J Hypertens 2002;15:321-325.
15. Chen CH, Nevo E, Fetics B, Pak PH, Yin FC, Maughan WL, Kass DA: Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure. Validation of generalized transfer function. Circulation 1997;95:1827-1836.
16. Fetics B, Nevo E, Chen CH, Kass DA: Parametric model derivation of transfer function for noninvasive estimation of aortic pressure by radial tonometry. IEEE Trans Biomed Eng 1999;46:698-706.
17. Hope SA, Tay DB, Meredith IT, Cameron JD: Comparison of generalized and gender-specific transfer functions for the derivation of aortic waveforms. Am J Physiol Heart Circ Physiol 2002;283: H1150-H1156.
18. Soderstrom S, Nyberg G, O'Rourke MF, Sellgren J, Ponten J: Can a clinically useful aortic pressure wave be derived from a radial pressure wave? Br J Anesth 2002;88:481-488.