Von Willebrand factor (VWF)-dependent human platelet activation: Porcine VWF utilizes different transmembrane signaling pathways than does thrombin to activate platelets, but both require protein phosphatase function

Journal of Thrombosis and Haemostasis

Volumn 1, Issue 2, 2003, Pages 337-346

  Song, S ^a   Mody, M ^a   Freedman, J ^a,b   Ellis, J ^a   Lazarus, A H ^a,b  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b CANADIAN BLOOD SERVICES   (Canada)

Author keywords

Phosphatase; Platelet; Thrombin; Transmembrane signaling; von Willebrand factor

Indexed keywords

ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; CALCIUM; FIBRINOGEN RECEPTOR; LEUKOCYTE ANTIGEN; LYSOSOMAL PROTEIN GP53; PADGEM PROTEIN; PHOSPHOPROTEIN PHOSPHATASE; THROMBIN; VON WILLEBRAND FACTOR;

ANIMAL; ARTICLE; BLOOD; CELL MEMBRANE; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; IN VITRO STUDY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; SWINE; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

ADENOSINE DIPHOSPHATE; ANIMALS; ANTIGENS, CD; BLOOD PLATELETS; CALCIUM; CELL MEMBRANE; HUMANS; P-SELECTIN; PHOSPHOPROTEIN PHOSPHATASE; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; SUS SCROFA; THROMBIN; VON WILLEBRAND FACTOR;

EID: 0141785252     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1046/j.1538-7836.2003.00050.x     Document Type: Article

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