Antihyperglycemic activity of Helicteres isora roots in alloxan-induced diabetic rats

Pharmaceutical Biology

Volumn 41, Issue 5, 2003, Pages 347-350

  Venkatesh, Sama ^a   Reddy, G Dayanand ^a   Reddy, B Madhava ^a  

^a G Pulla Reddy College of Pharmacy   (India)

Author keywords

Alloxan diabetic rats; Helicteres isora; Hypoglycemic activity; Roots; Sterculiaceae

Indexed keywords

ACETIC ACID ETHYL ESTER; ALCOHOL; ALLOXAN; ANTIDIABETIC AGENT; BUTANOL; CHLOROFORM; HELICTERES ISORA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; FRACTIONATION; GLUCOSE BLOOD LEVEL; HELICTERES ISORA; MALE; MEDICINAL PLANT; NONHUMAN; PLANT ROOT; RAT;

ANIMALIA; HELICTERES; MALVACEAE;

EID: 0141762645     PISSN: 13880209     EISSN: None     Source Type: Journal    
DOI: 10.1076/phbi.41.5.347.15937     Document Type: Article

References (14)

1. Batik BR, Dey AK, Das PC (1981): Helicteres isora Linn.; a new source of diosgenin. Ind J of Chem, Sect. B, 20B: 938-939.
2. Bean MF, Antoun M, Abrmson D, Chang CJ, McLaughlin JL, Cassady JM (1985): Cucurbitacin B and isocucurbitacin B: cytotoxic components of Helicteres isora. J Nat Prod 48: 500.
3. Holmann RR, Turner RC (1991): Oral agents and insulin in treatment of NIDDM. In: Pickup J, Williams G, Eds., Textbook of Diabetes. Oxford Blackwell, pp. 467-469.
4. Kameswara Rao B, Giri R, Kesavulu MM, Appa Rao Ch (1997): Herbal medicine: in the management of diabetes mellitus. Manpar Vaidhya Patrika I (4, 5): 33-35.
5. Kamiya K, Saiki Y, Hama T, Fujimoto Y, Endang H, Umar M, Satake T (2001): Flavonoid glucuronides from Helicteres isora. Phytochemistry 57: 297-301.
6. Kirthikar KR, Basu BD, An ICS (1981): Indian Medicinal Plants, Vol. 1, II, Allahabad Lalit Mohan Basu, India, pp. 370-372.
7. Pohocha N, Grampurohit ND (2001): Antispasmodic activity of the fruits of Helicteres isora Linn. Phytother Res 15: 49-52.
8. Romesh P, Yuvarajan CR (1995): A new flavone methyl ester from Helicteres isora. J Nat Prod 58: 1242-1243.
9. Saraswathi Bai N (1954): Chemical investigation of the stem bark of Helicteres isora. Bull Cent Res Inst, University Travancore, Trivandrurn, Sect A, 3: 89-107.
10. Satake T, Kamiya K, Saiki Y, Hama T, Fujimoto Y, Kitanaka S, Kimura Y, Uzawa J, Endang H, Umar M (1999): Studies on the constituents of fruits of Helicteres isora. Chem Pharm Bull 47: 1444-1447.
11. Singh SB, Singh AK, Thakur RS (1984): Chemical constituents of leaves of Helicteres isora. Ind J Pharm Sci 46: 148-149.
12. Tezuka Y, Terazono M, Kusumoto TI, Kawashima Y, Hatanaka Y, Kadota S, Hattori M, Namba T, Kikuchi T (1999): Helisterculins A and B, two new (7.5′, 8.2′)-neolignans and helisorin, the first (6.4′, 7.5′, 8.2′)-neolignan from the Indonesian medicinal plant Helicteres isora. Helv Chem Acta 82: 408-417.
13. Trease EG, Evans WC (1983): Textbook of Pharmacognosy, 12th ed., Oxford Alden Press, p. 539.
14. Trinder P (1969): Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann Clin Biochem 6: 24-27.