Analysis of histology specimens using lifetime multiphoton microscopy

Journal of Biomedical Optics

Volumn 8, Issue 3, 2003, Pages 376-380

  Eliceiri, Kevin W ^a   Fan, Ching Hua ^a,b   Lyons, Gary E ^a   White, John G ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b The Department of Electrical and Computer Engineering   (United States)

Author keywords

Fluorescence lifetime imaging; Multiphoton microscopy

Indexed keywords

FLUORESCENCE; LIGHT SCATTERING; PATHOLOGY; PHOTONS; TISSUE;

MULTIPHOTON MICROSCOPY;

MEDICAL IMAGING;

PRIMATES;

4',6 DIAMIDINO 2 PHENYLINDOLE; CARBOCYANINE; CYANINE DYE 3; CYTOSKELETON PROTEIN; DNA; INDOLE DERIVATIVE;

ANIMAL; ARTICLE; CAENORHABDITIS ELEGANS; CELL NUCLEUS; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CYTOLOGY; CYTOPLASM; EVALUATION; FEASIBILITY STUDY; METABOLISM; METHODOLOGY; MULTIPHOTON MICROSCOPY; PRENATAL DEVELOPMENT; ULTRASTRUCTURE; VALIDATION STUDY;

ANIMALS; CAENORHABDITIS ELEGANS; CARBOCYANINES; CELL NUCLEUS; CYTOPLASM; CYTOSKELETAL PROTEINS; DNA; FEASIBILITY STUDIES; INDOLES; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE, MULTIPHOTON;

EID: 0141756186     PISSN: 10833668     EISSN: None     Source Type: Journal    
DOI: 10.1117/1.1584053     Document Type: Article

References (12)

1. J. E. Pawley, Handbook of Confocal Microscopy, Plenum, New York (1996).
2. W. Denk, J. H. Strickler, and W. W. Webb, "Two-photon laser scanning fluorescence microscopy," Science 248(4951), 73-76 (1990).
3. C. Thomas et al., "Four-dimensional imaging: computer visualization of 3D movements in living specimens," Science 273(5275), 603-607 (1996).
4. J. R. Lakowicz, Principles of Fluorescence Microscopy, 2nd ed., Kluwer Academic/Plenum, New York (1999).
5. J. R. Lakowicz et al., "Fluorescence lifetime imaging," Anal. Biochem. 202(2), 316-330 (1992).
6. X. F. Wang, A. Periasamy, and B. Herman, "Fluorescence lifetime imaging microscopy (FLIM): instrumentation and applications," Crit. Rev. Anal. Chem. 23, 365-3369 (1992).
7. T. W. J. Gadella, T. M. Jovin, and R. M. Clegg, "Fluorescence lifetime imaging microscopy (FLIM): spatial resolution of microstructures on the nanosecond time scale," Biophys. Chem. 48, 221-239 (1993).
8. P. I. Bastiaens and A. Squire, "Fluorescence lifetime imaging microscopy: spatial resolution of biochemical processes in the cell," Trends Cell Biol. 9(2), 48-52 (1999).
9. M. J. Cole et al., "Time-domain whole-field fluorescence lifetime imaging with optical sectioning," J. Microsc. 203(Pt. 3), 246-257 (2001).
10. H. C. Gerritsen et al., "The photon economy of fluorescence lifetime imaging," Scanning 18, 55-56 (1996).
11. H. C. Gerritsen and K. de Grauw, "One and two-photon confocal fluorescence lifetime imaging and its applications," in Methods in Cellular Imaging, A. Periasamy, Ed., pp. 309-323, Oxford University Press, New York (2001).
12. V. E. Centonze and J. G. White, "Multiphoton excitation provides optical sections from deeper within scattering specimens than confocal imaging," Biophys. J. 75(4), 2015-2024 (1998).