Using technetium-99m methoxyisobutylisonitrile lung single-photon-emission computed tomography to predict response to chemotherapy and compare with P-glycoprotein expression in patients with untreated small cell lung cancer

Medical Oncology

Volumn 20, Issue 3, 2003, Pages 247-253

  Changlai, Sheng Pin ^a   Tsai, Chang Shu ^b   Ding, Hueisch Jy ^c   Huang, Wen Tao ^d   Kao, Albert ^e   Hsu, Wu Huei ^e  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b TZU CHI COLLEGE OF TECHNOLOGY   (Taiwan)

^c I SHOU UNIVERSITY   (Taiwan)

^d YUANPEI UNIVERSITY   (Taiwan)

^e CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Chemotherapy; P glycoprotein; Single photon emission computed tomography; Small cell lung cancer; Technetium 99m methoxyisobutylisonitrile

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; ETOPOSIDE; GLYCOPROTEIN P; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; TECHNETIUM 99M;

ACCURACY; ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER PATIENT; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; MALE; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TREATMENT OUTCOME; TUMOR BIOPSY;

AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SMALL CELL; CISPLATIN; ETOPOSIDE; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; P-GLYCOPROTEIN; RADIOPHARMACEUTICALS; RETROSPECTIVE STUDIES; TECHNETIUM TC 99M SESTAMIBI; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0141748379     PISSN: 13570560     EISSN: None     Source Type: Journal    
DOI: 10.1385/MO:20:3:247     Document Type: Article

References (22)

1. Lassen U, Hansen HH: Small cell carcinoma of the lung. In Cancer treatment, edited by CM Haskell, JS Berek, Philadelphia, W B Saunders, 1995, pp. 414-420.
2. Smit EF, Postmus PE: Chemotherapy of small cell lung cancer. In Carney DN (ed). Lung cancer. The Bath Press, Avon, London, 1995, pp. 156-172.
3. Berlin J, Schiller JH: Chemotherapy of small-cell carcinoma of the lung. In Johnson BE, Johnson DH (eds). Lung cancer. Wiley-Liss, New York, 1995, pp. 247-261.
4. Oka M, et al. The clinical role of MDR1 gene expression in human lung cancer. Anticancer Res 1997;17:721-724.
5. Twentyman PR. Mechanism of drug resistance in lung cancer cells. In Carney DN (ed). Lung cancer. The Bath Press, Avon, London. 1995.
6. Beck W, Dalton WS: Mechanisms of drug resistance. In DeVita VT Jr, et al. (eds.) Cancer: principles and practice of oncology. JB Lippincott, Philadelphia, 1997.
7. Piwnica-Worms D, et al. Functional imaging of multidrug-resistant P-glycoprotein with an organotechnetium complex. Cancer Res 1993;53:977-984.
8. Hendrikse NH, et al. Visualization of multidrug resistance in vivo. Eur J Nucl Med 1999;26:283-293.
9. Vergote J, et al. Comparison of the kinetics of active efflux of 99mTc-MIBI in cells with P-glycoprotein-mediated and multidrug-resistance protein-associated multidrug-resistance phenotypes. Eur J Biochem 1998;252:140-146.
10. Hendrikse NH, et al. 99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein. Br J Cancer 1998;77:353-358.
11. Yamamoto Y, et al. Comparative study of technetium-99m-sestamibi and thallium-201 SPECT in predicting chemotherapeutic response in small cell lung cancer. J Nucl Med 1998;39:1626-1629.
12. Kao CH, et al. Technetium-99m methoxyisobutylisonitrile chest imaging of small cell lung carcinoma: relation to patient prognosis and chemotherapy response - a preliminary report. Cancer 1998;83:64-68.
13. Kao CH, et al. Quickly predicting chemotherapy response to paclitaxel-based therapy in non-small cell lung cancer by early technetium-99m methoxyisobutylisonitrile chest single photon emission computed tomography. Clin Cancer Res 2000;6:820-824.
14. Oken MM, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 1982;5:649-655.
15. Aktolun C, et al. Assessment of tumour necrosis and detection of mediastinal lymph node metastasis in bronchial carcinoma with technetium-99m MIBI imaging: comparison with CT scan. Eur J Nucl Med 1994;21:973-979.
16. Kao CH, et al. Differentiation of single solid lesions in the lungs by means of single-photon emission tomography with technetium-99m methoxyisobutylisonitrile. Eur J Nucl Med 1993;20:249-254.
17. Kostakoglu L, et al. Association of tumor washout rates and accumulation of technetium-99m-MIBI with expression of P-glycoprotein in lung cancer. J Nucl Med 1998;39:228-234.
18. Kreisholt J, et al. Immunohistochemical detection of DNA topoisomerases II α, p-glycoprotein and multidrug resistance protein (MRP) in small-cell and non-small-cell lung cancer. Br J Cancer 1998;77:1469-1473.
19. Chuman Y, et al. Expression of the multidrug-resistance-associated protein (MRP) gene in human colorectal, gastric and non-small-cell lung carcinomas. Int J Cancer 1996;66:274-279.
20. Karnofsky DA, et al. The use of nitrogen mustards in the palliative treatment of cancer. Cancer 1948;1:634-656.
21. Neal AJ, Hoskin PJ: Lung cancer and mesothelioma. In Neal AJ, Hoskin PJ (eds). Clinical oncology: basic principles and practice. Arnold, London, 1997, pp. 42-55.
22. Canitrot Y, et al. Multidrug resistance genes (MRP) and MDRI expression in small cell lung cancer xenografts: relationship with response to chemotherapy. Cancer Lett 1998;130:133-141.