Age-dependent impairment of somatosensory response in the amyloid precursor protein 23 transgenic mouse model of Alzheimer's disease

Journal of Neuroscience

Volumn 23, Issue 23, 2003, Pages 8231-8236

  Mueggler, Thomas ^a,b   Baumann, Diana ^a   Rausch, Martin ^a   Staufenbiel, Matthias ^a   Rudin, Markus ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Alzheimer's disease; Amyloid precursor protein; APP; fMRI; Functional magnetic resonance imaging; Hindpaw; Peripheral stimulation; Relative cerebral blood volume; Somatosensory cortex; Transcutaneous blood gas monitoring; Transgenic mice

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN 23; UNCLASSIFIED DRUG;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD VOLUME; BRAIN CIRCULATION; BRAIN FUNCTION; BRAIN MAPPING; DISEASE COURSE; ELECTROSTIMULATION; HEMODYNAMICS; MOUSE; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SOMATOSENSORY CORTEX; SOMATOSENSORY DISORDER; TRANSGENIC MOUSE;

EID: 0141744905     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-23-08231.2003     Document Type: Article

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