Alpha-internexin expression in medulloblastomas and atypical teratoid-rhabdoid tumors

Clinical Neuropathology

Volumn 22, Issue 5, 2003, Pages 215-221

  Kaya, B ^a   Mena, H ^b   Miettinen, M ^b   Rushing, E J ^b  

^a QUEEN S MEDICAL CENTER   (United States)

^b ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

Author keywords

internexin; Atypical teratoid rhabdoid tumor; Immunohistochemistry; Medulloblastoma; Primitive neuroectodermal tumor

Indexed keywords

ALPHA INTERNEXIN; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERMEDIATE FILAMENT PROTEIN; PERIPHERIN; SYNAPTOPHYSIN;

ADOLESCENT; ADULT; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CHILD; CLINICAL ARTICLE; DESMOPLASTIC MEDULLOBLASTOMA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MEDULLOBLASTOMA; MEDULLOMYOBLASTOMA; NERVE CELL; NERVE CELL DIFFERENTIATION; NEUROECTODERM TUMOR; NODULAR MEDULLOBLASTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHABDOID TUMOR; STAINING; TERATOMA;

ADOLESCENT; ADULT; CARRIER PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; CEREBELLAR NEOPLASMS; CEREBELLUM; CHILD; CHILD, PRESCHOOL; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; IMMUNOENZYME TECHNIQUES; INFANT; INTERMEDIATE FILAMENT PROTEINS; MALE; MEDULLOBLASTOMA; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; NEURONS; RHABDOID TUMOR; SYNAPTOPHYSIN; TERATOMA;

EID: 0141737806     PISSN: 07225091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Bailey P, Cushing H 1925 Medulloblastoma cerebelli; a common type of midcerebellar glioma of childhood. Arch Neurol and Psychiatry 14: 192-224
2. Bambakidis NC, Robinson S, et al 2002 Atypical teratoid/rhabdoid tumors of the central nervous system: clinical, radiographic and pathologic features. Pediatr Neurosurg 37: 64-70
3. Brown HG, Kepner JL, et al 2000 Large cell/anaplastic medulloblastomas: a Pediatric Oncology Group Study. J Neuropathol Exp Neurol 59: 857-865
4. Bruch LA, Hill DA, et al 2001 A role for fluorescence in situ hybridization detection of chromosome 22q dosage in distinguishing atypical teratoid/rhabdoid tumors from medulloblastoma/central primitive neuroectodermal tumors. Hum Path 32: 156-162
5. Burger PC, Grahmann FC, et al 1987 Differentiation in the medulloblastoma. A histological and immunohistochemical study. Acta Neuropathol (Berl) 73: 115-123
6. Burger PC, Yu IT, et al 1998 Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma: a Pediatric Oncology Group Study. Am J Surg Pathol 22: 1083-1092
7. Caputy AJ, McCullough DC, et al 1987 A review of the factors influencing the prognosis of medulloblastoma. The importance of cell differentiation. J Neurosurg 66: 80-87
8. Chien CL, Mason CA, et al 1996 Internexin is the only neuronal intermediate filament expressed in developing cerebellar granule neurons. J Neurobiol 29: 304-318
9. Coffin CM, Braun JT, et al 1990 A clinicopathologic and immunohistochemical analysis of 53 cases of medulloblastoma with emphasis on synaptophysin expression. Mod Path 3: 164-170
10. Crino PB, Trojanowski JQ, et al 1997 Internexin, MAP1B, and nestin in cortical dysplasia as markers of developmental maturity. Acta Neuropathol (Berl) 93: 619-627
11. Czerwionka M, Korf HW, et al 1989 Differentiation in medulloblastomas: correlation between the immunocytochemical demonstration of photoreceptor markers (S-antigen, rod-opsin) and the survival rate in 66 patients. Acta Neuropathol (Berl) 78: 629-636
12. Eberhart CG, Kepner JL, et al 2002 Histopathologic grading of medulloblastomas: a Pediatric Oncology Group Study. Cancer. Cancer 94: 552-560
13. Foley J, Witte D, et al 1994 Expression of the neural intermediate filament proteins peripherin and neurofilament-66/alpha-internexin in neuroblastoma. Lab Invest 71: 193-199
14. Giangaspero F, Chieco P, et al 1991 "Desmoplastic" versus "classic" medulloblastoma: comparison of DNA content, histopathology and differentiation. Virchows Arch A Pathol Anat Histopathol 418: 207-214
15. Goldberg-Stern H, Gadoth N, et al 1991 The prognostic significance of glial fibrillary acidic protein staining in medulloblastoma. Cancer 68: 568-573
16. Ho CL, Liem RKH 1996 Intermediate filaments in the nervous system: implications in cancer. Cancer Metastasis Rev 15: 483-497
17. Janss AJ, Yachnis AT, et al 1996 Glial differentiation predicts poor clinical outcome in primitive neuroectodermal brain tumors. Ann Neurol 39: 481-489
18. Kaplan MP, Chin SS, et al 1990 Alpha-internexin, a novel neuronal intermediate filament protein, precedes the low molecular weight neurofilament protein (NF-L) in the developing rat brain. J Neurosci 10: 2735-2748
19. Kasantikul V, Shuangshoti S 1986 Cerebellar medulloblastomas: a study of 35 cases with particular reference to cellular differentiation. Surg Neurol 26: 532-541
20. Kleihues P, Cavenee WK 2000 Pathology and genetics of tumors of the nervous system. International Agency for Research, Lyon
21. Kleihues P, Louis DN, et al 2002 The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 61 (3): 215-225
22. Maraziotis T, Perentes E, et al 1992 Neuron-associated class III beta-tubulin isotype, retinal S-antigen, synaptophysin, and glial fibrillary acidic protein in human medulloblastomas: a clinicopathological analysis of 36 cases. Acta Neuropathol (Berl) 84: 355-363
23. Molenaar WM, Jansson DS, et al 1989 Molecular markers of primitive neuroectodermal tumors and other pediatric central nervous system tumors: monoclonal antibodies to neuronal and glial antigens distinguish subsets of primitive neuroectodermal tumors. Lab Invest 61: 635-643
24. Packer RJ, Sutton LN, et al 1984 Prognostic importance of cellular differentiation in medulloblastoma of childhood. J Neurosurg 61: 296-301
25. Packer RJ, Biegel JA, et al 2002 Atypical teratoid/rhabdoid tumor of the central nervous system: report on workshop. J Pediatr Hematol Oncol 24: 337-342
26. Palmer JO, Kasselberg AG, et al 1981 Differentiation of medulloblastoma. Studies including immunohistochemical localization of glial fibrillary acidic protein. J Neurosurg 55: 161-169
27. Perry A, Scheithauer BW, et al 1998 "Rhabdoid" meningioma: an aggressive variant. Am J Surg Pathol 22: 1482-1490
28. Rorke LB, Packer R, et al 1995 Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood. J Neurooncol 24: 21-28
29. Rorke LB, Packer RJ, et al 1996 Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood: definition of an entity. J Neurosurg 85: 56-65
30. Rubin JB, Rowitch DH 2002 Medulloblastoma: a problem of developmental biology. Cancer Cell 2: 7-8
31. Schwecheimer K, Wiedenmann B, et al 1987 Synaptophysin: a reliable marker for medulloblastomas. Virchows Arch (A) 411: 53-59
32. Tamiya T, Nakashima H, et al 2000 Spinal atypical teratoid/rhabdoid tumor in an infant. Pediatr Neurosurg 32: 145-149
33. Uno K, Takita J, et al 2002 Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors. Genes Chromosomes Cancer 34: 33-41
34. Wang H, Wang H, et al 2002 Tissue microarrays: applications in neuropathology research, diagnosis, and education. Brain Pathol 12: 95-107
35. Wyatt-Ashmead J, Kleinschmidt-DeMasters BK, et al 2001 Rhabdoid glioblastoma. Clin Neuropathol 20: 248-255
36. Yachnis AT, Rorke LB, et al 1992 Desmoplastic primitive neuroectodermal tumor with divergent differentiation. Broadening the spectrum of desmoplastic infantile neuroepithelial tumors. Am J Surg Pathol 16: 998-1006