Utility of in vitro closure time test for evaluating platelet-related primary hemostasis in dialysis patients

American Journal of Kidney Diseases

Volumn 42, Issue 4, 2003, Pages 746-751

  Zupan, Irena Preložnik ^a   Šabovič, Mišo ^b   Salobir, Barbara ^b   Ponikvar, Jadranka Buturovič ^b   Černelč, Peter ^b  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^b NONE

Author keywords

Hemostasis; In vitro closure time; Platelet aggregation; Renal insufficiency; Skin bleeding time

Indexed keywords

ADENOSINE DIPHOSPHATE; ADRENALIN; COLLAGEN;

ADULT; AGED; ARTICLE; BLEEDING TIME; BLOOD VESSEL INJURY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; DIALYSIS; FEMALE; HEMOSTASIS; HUMAN; IN VITRO CLOSURE TIME TEST; INTERMETHOD COMPARISON; KIDNEY FAILURE; MALE; SENSITIVITY AND SPECIFICITY; SKIN BLEEDING; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION;

EID: 0141732145     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0272-6386(03)00913-2     Document Type: Article

References (26)

1. Remuzzi G: Bleeding disorders in uremia: Pathophysiology and treatment. Adv Nephrol 18:171-186, 1989
2. Eberst ME, Berkowitz LR: Hemostasis in renal disease: Pathophysiology and management. Am J Med 96:168-179, 1994
3. Rabelink TJ, Zwaginga JJ, Koomans HA, Sixma JJ: Thrombosis and hemostasis in renal disease. Kidney Int 46:287-296, 1994
4. Rao AK: Uraemic platelets. Lancet 1:913-914, 1986
5. Weigert AL, Schafer AI: Uremic bleeding: Pathogenesis and therapy. Am J Med Sci 316:94-104, 1998
6. Mezzano D, Tagle R, Panes O, et al: Hemostatic disorder of uremia: The platelet defect, main determinant of prolonged bleeding time, is correlated with indices of activation of coagulation and fibrinolysis. Thromb Haemost 76:312-321, 1996
7. Noris M, Remuzzi G: Uremic bleeding: Closing the circle after 30 years of controversies? Blood 94:2569-2574, 1999
8. Remuzzi G: Bleeding in renal failure. Lancet 1:1205-1208, 1988
9. Livio M, Marchesi D, Remuzzi G: Coagulation abnormalities in uremia. Semin Nephrol 5:82-90, 1985
10. Steiner RW, Coggins C, Carvalho AC: Bleeding time in uremia: a useful test to assess clinical bleeding. Am J Hematol 7:107-117, 1979
11. Marchant KK, Corcoran G: The laboratory diagnosis of platelet disorders. An algorithmic approach. Arch Pathol Lab Med 126:133-146, 2002
12. Mattix H, Singh AK: Is the bleeding time predictive of bleeding prior to a percutaneous renal biopsy? Curr Opin Nephrol Hypertens 8:715-718, 1999
13. Lehman CM, Blaylock RC, Alexander DP, Rodgers GM: Discontinuation of the bleeding time test without detectable adverse clinical impact. Clin Chem 47:1204-1211, 2001
14. Kratzer MAA, Born GVR: Platelet function defects: Simulation of primary hemostasis in vitro. Hemostasis 18: 167-185, 1985
15. Kundu SK, Heilmann EJ, Sio R, Garcia C, Davidson R, Ostgaard RA: Description of an in vitro platelet function analyzer PFA-100. Semin Thromb Hemostasis 21:106-112, 1995(suppl 2)
16. Mammen EF, Comp PC, Gosselin R, et al: PFA-100™ System: A new method for assessment of platelet dysfunction. Semin Thromb Hemostasis 24:195-202, 1998
17. Favaloro EJ: Utility of the PFA-100 for assessing bleeding disorders and monitoring therapy: A review of analytical variables, benefits and limitations. Haemophilia 7:170-179, 2001
18. Marshall PW, Williams AJ, Dixon RM, et al: A comparison of the effects of aspirin on bleeding time measured using the Simplate™ method and closure time measured using the PFA-100™, in healthy volunteers. Br J Clin Pharmacol 44:151-155, 1997
19. Marietta M, Castelli I, Piccinini F, et al: The PFA-100 system for the assessment of platelet function in normotensive and hypertensive pregnancies. Clin Lab Haematol 23: 131-134, 2001
20. Serebruany VL, Alford A, Meister AF, et al: Clinical utility of the platelet function analyzer (PFA-100) for the assessment of the platelet status in patients with congestive heart failure (EPCOT trial). Thromb Res 15:427-433, 2001
21. Laffan MA, Manning RA: Investigation of hemostasis, in Lewis SM (ed): Practical Haematology (ed 9). New York, NY, Churchill Livingstone, 2001, pp 339-390
22. Born GVR: Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature 194:927-929, 1962
23. Santoro SA, Eby CS: Laboratory evaluation of hemostatic disorders, in Hoffman R (ed): Hematology: Basic Principles and Practise (ed 3). New York, NY, Churchill Livingstone, 2000, pp 1841-1850
24. Favaloro EJ: Clinical application of the PFA-100. Curr Opin Hematol 9:407-415, 2002
25. Escolar G, Cases A, Vinas M, et al: Evaluation of acquired platelet dysfunctions in uremic and cirrotic patients using the platelet function analyser (PFA-100™): Influence of hematocrit elevation. Haematologica 84:614-619, 1999
26. Salat A, Kroess S, Felfernig-Boehm D, et al: Comparison of in vitro closure time (PFA-100) with whole blood electrical aggregometry and platelet surface antigen expression in healthy volunteers. Thromb Res 105:205-208, 2002