Efficacy of controlled-release paroxetine in the treatment of late-life depression

Journal of Clinical Psychiatry

Volumn 64, Issue 9, 2003, Pages 1065-1074

  Rapaport, Mark Hyman ^a   Schneider, Lon S ^b   Dunner, David L ^c   Davies, John T ^d   Pitts, Cornelius D ^e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d GLAXOSMITHKLINE   (United Kingdom)

^e GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PAROXETINE; PLACEBO;

AGED; ANOREXIA; ARTICLE; ASTHENIA; BODY WEIGHT; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DEPRESSION; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DYSPEPSIA; EJACULATION DISORDER; ELECTROCARDIOGRAPHY; FEMALE; GERIATRIC DISORDER; HAMILTON SCALE; HEADACHE; HEART ARRHYTHMIA; HUMAN; HYPOTENSION; INSOMNIA; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; NERVOUSNESS; PATIENT COMPLIANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; REMISSION; SOMNOLENCE; TREATMENT OUTCOME; XEROSTOMIA;

EID: 0141717237     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.v64n0912     Document Type: Article

References (40)

1. Gallo JJ, Rabins PV, Lyketsos CG, et al. Depression without sadness: functional outcomes of nondysphoric depression in later life. J Am Geriatr Soc 1997;45:570-578
2. Huang BY, Cornoni-Huntley J, Hays JC, et al. Impact of depressive symptoms on hospitalization risk in community-dwelling older persons. J Am Geriatr Soc 2000;48:1279-1284
3. Zubenko GS, Mulsant BH, Sweet RA, et al. Mortality of elderly patients with psychiatric disorders. Am J Psychiatry 1997;154:1360-1368
4. Unützer J, Katon W, Russo J, et al. Patterns of care for depressed older adults in a large-staff model HMO. Am J Geriatr Psychiatry 1999;7:235-243
5. Bondareff W, Alpert M, Friedhoff AJ, et al. Comparison of sertraline and nortriptyline in the treatment of major depressive disorder in late life. Am J Psychiatry 2000;157:729-736
6. Cassano GB, Puca F, Scapicchio PL, et al, for the Italian Group on Depression in Elderly. Paroxetine and fluoxetine effects on mood and cognitive functions in depressed nondemented elderly patients. J Clin Psychiatry 2002;63:396-402
7. Mulsant BH, Pollock BG, Nebes RD, et al. A double-blind randomized comparison of nortriptyline and paroxetine in the treatment of late-life depression: 6-week outcome. J Clin Psychiatry 1999;60(suppl 20):16-20
8. Schöne W, Ludwig M. A double-blind study of paroxetine compared with fluoxetine in geriatric patients with major depression. J Clin Psychopharmacol 1993;13(suppl 2):34S-39S
9. Emslie G, Judge R. Tricyclic antidepressants and selective serotonin reuptake inhibitors: use during pregnancy, in children/adolescents and in the elderly. Acta Psychiatr Scand Suppl 2000;403:26-34
10. Nyth AL, Gottfries CG, Lyby K, et al. A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia. Acta Psychiatr Scand 1992;86:138-145
11. Tollefson GD, Bosomworth JC, Heiligenstein JH, et al, and the Fluoxetine Collaborative Study Group. A double-blind, placebo-controlled clinical trial of fluoxetine in geriatric patients with major depression. Int Psychogeriatr 1995;7:89-104
12. Schneider LS, Clary C, Finkel SI, et al. Sertraline in the treatment of elderly depression: results of a large, multicenter, placebo-controlled trial [poster]. Presented at the 154th annual meeting of the American Psychiatric Association; May 5-10, 2001; New Orleans, La
13. Golden RN, Nemeroff CB, McSorley P, et al. Efficacy and tolerability of controlled-release and immediate-release paroxetine in the treatment of depression. J Clin Psychiatry 2002;63:577-584
14. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: American Psychiatric Association; 1994
15. First MB, Spitzer RL, Gibbon M, et al. Structured Clinical Interview for DSM-IV. New York, NY: Biometric Research, New York State Psychiatric Institute; 1995
16. Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967;6:278-296
17. Stern Y, Sabo M, Paulson J, et al. Modified Mini-Mental State Examination: validity and reliability [abstract]. Neurology 1987;37(1, suppl):179
18. Guy W. ECDEU Assessment Manual for Psychopharmacology. US Dept Health, Education, and Welfare publication (ADM) 76-338. Rockville, Md: National Institute of Mental Health; 1976:218-222
19. Ballenger JC. Clinical guidelines for establishing remission in patients with depression and anxiety. J Clin Psychiatry 1999;60(suppl 22):29-34
20. Thase ME, Entsuah AR, Rudolph RL. Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. Br J Psychiatry 2001;178:234-241
21. Keller MB, McCullough JP, Klein DN, et al. A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression. N Engl J Med 2000;342:1462-1470
22. Dunner DL, Cohn JB, Walshe T III, et al. Two combined, multicenter double-blind studies of paroxetine and doxepin in geriatric patients with major depression. J Clin Psychiatry 1992;53(suppl 2):57-60
23. Høyberg OJ, Maragakis B, Mullin J, et al. A double-blind multicentre comparison of mirtazapine and amitriptyline in elderly depressed patients. Acta Psychiatr Scand 1996;93:184-190
24. Mulsant BH, Pollock BG, Nebes R, et al. A twelve-week, double-blind, randomized comparison of nortriptyline and paroxetine in older depressed inpatients and outpatients. Am J Geriatr Psychiatry 2001;9:406-414
25. Devanand DP, Nobler MS, Singer T, et al. Is dysthymia a different disorder in the elderly? Am J Psychiatry 1994;151:1592-1599
26. Reynolds CF III, Dew MA, Frank E, et al. Effects of age at onset of first lifetime episode of recurrent major depression on treatment response and illness course in elderly patients. Am J Psychiatry 1998;155:795-799
27. Schulberg HC, Mulsant B, Schulz R, et al. Characteristics and course of major depression in older primary care patients. Int J Psychiatry Med 1998;28:421-436
28. Thase ME, Rush AJ, Howland RH, et al. Double-blind switch study of imipramine or sertraline treatment of antidepressant-resistant chronic depression. Arch Gen Psychiatry 2002;59:233-239
29. Keller MB, Kocsis JH, Thase ME, et al. Maintenance phase efficacy of sertraline for chronic depression: a randomized controlled trial. JAMA 1998;280:1665-1672
30. Kocsis JH, Friedman RA, Markowitz JC, et al. Maintenance therapy for chronic depression: a controlled clinical trial of desipramine. Arch Gen Psychiatry 1996;53:769-774
31. Khan A, Dager SR, Cohen S, et al. Chronicity of depressive episode in relation to antidepressant-placebo response. Neuropsychopharmacology 1994;4:125-130
32. Friedman R. Social impairment in dysthymia. Psychiatr Ann 1993;23:632-637
33. Nelson JC. Diagnosing and treating depression in the elderly. J Clin Psychiatry 2001;62(suppl 24):18-22
34. Kornstein SG, Schatzberg AF, Thase ME, et al. Gender differences in treatment response to sertraline versus imipramine in chronic depression. Am J Psychiatry 2000;157:1445-1452
35. Schneider LS, Small GW, Clary CM. Estrogen replacement therapy and antidepressant response to sertraline in older depressed women. Am J Geriatr Psychiatry 2001;9:393-399
36. Schneider LS, Small GW, Hamilton SH, et al, and the Fluoxetine Collaborative Study Group. Estrogen replacement and response to fluoxetine in a multicenter geriatric depression trial. Am J Geriatr Psychiatry 1997;5:97-106
37. Mulsant BH, Pollock BG. Treatment-resistant depression in late life. J Geriatr Psychiatry Neurol 1998;11:186-193
38. Balkrishnan R. Predictors of medication adherence in the elderly. Clin Ther 1998;20:764-771
39. Coons SJ, Sheahan SL, Martin SS, et al. Predictors of medication noncompliance in a sample of older adults. Clin Ther 1994;16:110-117
40. Walters G, Reynolds CF III, Mulsant BH, et al. Continuation and maintenance pharmacotherapy in geriatric depression: an open-trial comparison of paroxetine and nortriptyline in patients older than 70 years. J Clin Psychiatry 1999;60(suppl 20):21-25