Mucosal activity patterns as a basis for olfactory discrimination: Comparing behavior and optical recordings

Brain Research

Volumn 981, Issue 1-2, 2003, Pages 1-11

  Kent, P F ^a   Mozell, M M ^a,b   Youngentob, S L ^a   Yurco, P ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

Behavior; Mucosal activity pattern; Odorant quality perception; Optical imaging; Rat

Indexed keywords

ALDEHYDE DERIVATIVE; 1 (3 SULFONATOPROPYL) 4 (BETA)(2 (DI N BUTYLAMINO) 6 NAPHTHYLVINYL)PYRIDINIUM BETAINE; 1-(3-SULFONATOPROPYL)-4-(BETA)(2-(DI-N-BUTYLAMINO)-6-NAPHTHYLVINYL)PYRIDINIUM BETAINE; ALDEHYDE; FLUORESCENT DYE; PYRIDINIUM DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA ANALYSIS; INSTRUMENTAL CONDITIONING; NEUROPHYSIOLOGY; NONHUMAN; ODOR; OLFACTORY DISCRIMINATION; OLFACTORY EPITHELIUM; PERCEPTION; PRIORITY JOURNAL; RAT; VISUAL SYSTEM; ANIMAL; ANIMAL BEHAVIOR; BRAIN MAPPING; COMPARATIVE STUDY; DIAGNOSTIC IMAGING; DISCRIMINATION LEARNING; DOSE RESPONSE; DRUG EFFECT; HISTOLOGY; INDIVIDUALITY; LONG EVANS RAT; METHODOLOGY; NOSE SEPTUM; PERCEPTIVE THRESHOLD; PHYSIOLOGY; PSYCHOPHYSICS; STIMULATION; TURBINATE;

ALDEHYDES; ANIMALS; BEHAVIOR, ANIMAL; BRAIN MAPPING; CONDITIONING, OPERANT; DIAGNOSTIC IMAGING; DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCENT DYES; INDIVIDUALITY; NASAL SEPTUM; ODORS; OLFACTORY MUCOSA; PERCEPTION; PSYCHOPHYSICS; PYRIDINIUM COMPOUNDS; RATS; RATS, LONG-EVANS; SENSORY THRESHOLDS; SMELL; STIMULATION, CHEMICAL; TURBINATES;

EID: 0141687007     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(03)02512-5     Document Type: Article

References (33)

1. Adrian E.D. Sensory discrimination with some recent evidence from the olfactory organ. Br. Med. Bull. 6:1950;330-331.
2. Adrian E.D. Olfactory discrimination. Ann. Psychol. 50:1951;107-130.
3. Buck L., Axel R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell. 65:1991;175-187.
4. Buck L. Information coding in the vertebrate olfactory system. Annu. Rev. Neurosci. 19:1996;517-544.
5. Bennet M.H. Effects of asymmetrical mucosal stimulation upon two-odor discrimination in the rat. Physiol. Behav. 9:1972;301-306.
6. Cinelli A.R., Hamilton K.A., Kauer J.S. Salamander olfactory bulb neuronal activity observed by video rate, voltage-sensitive dye imaging. III. Spatial and temporal properties of responses evoked by odorant stimulation. J. Neurophysiol. 73:1995;2053-2070.
7. Ezeh P.I., Davis L.M., Scott J.W. Regional distribution of rat electroolfactogram. J. Neurophysiol. 73:1995;2207-2220.
8. C.L. Iwema, Patterns of odorant receptor expression and axonal projection in the lesioned-recovered peripheral olfactory system, Dissertation, Upstate Medical University, 2001.
9. Kauer J.S., Moulton D.G. Response to olfactory bulb neurons to odor stimulation of small nasal areas in the salamander. J. Physiol. Lond. 243:1974;717-737.
10. Kent P.F., Mozell M.M. The recording of odorant-induced mucosal activity patterns with a voltage-sensitive dye. J. Neurophysiol. 68:1992;1804-1819.
11. Kent P.F., Youngentob S.L., Sheehe P.R. Odorant-specific patterns in mucosal activity predict perceptual differences among odorants. J. Neurophysiol. 74:1995;1777-1781.
12. Kent P.F., Mozell M.M., Murphy S.J., Hornung D.E. The interaction of imposed and inherent olfactory mucosal activity patterns and their composite representation in a mammalian species using voltage-sensitive dyes. J. Neurosci. 16:1996;345-353.
13. Kubie J.L MacKay-Sim A., Moulton D.G. Inherent spatial patterning of response to odorants in the salamander olfactory epithelium. Van der Starr H. Olfaction and Taste VII. 1980;163-166 IRL, London.
14. Linster C. C, Johnson B.A., Yue E., Morse A., Xu Z., Hingo E.E., Choi Y., Choi M., Messiha A., Leon M. Perceptual correlates of neural representations evoked by odorant enantiomers. J. Neurosci. 21:2001;9837-9843.
15. MacKay-Sim A., Kubie J.L. The salamander nose: a model system for the study of spatial coding of olfactory quality. Chem. Senses. 6:1981;249-257.
16. MacKay-Sim A., Shaman P., Moulton D.G. Topographic coding of olfactory quality: odorant specific patterns of epithelial responsivity in the salamander. J. Neurophysiol. 48:1982;584-596.
17. MacKay-Sim A., Kesteven S. Topographic patterns of responsiveness to odorants in the rat olfactory epithelium. J. Neurophysiol. 71:1994;150-160.
18. Mombaerts P., Wang F., Dulac C., Chao S.K., Nemes A., Mendelsohn M., Edmondson J., Axel R. Visualizing an olfactory sensory map. Cell. 87:1996;675-686.
19. Moulton D.G. Spatial patterning response to odors in the peripheral olfactory system. Physiol. Rev. 56:1976;578-593.
20. Mozell M.M. The spatiotemporal analysis of odorants at the level of the olfactory receptor sheet. J. Gen. Physiol. 50:1966;25-41.
21. Mozell M.M., Jagodowicz M. Mechanisms underlying the analysis of odorant quality at the level of the olfactory mucosa. I. Spatiotemporal sorption patterns. Ann. N. Y. Acad. Sci. 237:1974;76-90.
22. Ressler K.J., Sullivan S.L., Buck L.B. A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell. 73:1993;597-609.
23. Ressler K.J., Sullivan S.S., Buck L.B. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell. 79:1994;1245-1255.
24. P.W. Scherer, personal communication.
25. Scott J., Shannon D., Carpentier J., Davis L., Kaplan C. Spatially organized response zones in rat olfactory epithelium. J. Neurophysiol. 77:1997;1950-1965.
26. Strotmann J., Wanner I., Helfrich T., Beck A., Breer H. Rostro-caudal patterning of receptor-expressing olfactory neurones in the rat nasal cavity. Cell Tissue Res. 278:1994;11-12.
27. Thommesen G., Doving K.B. Spatial distribution of the EOG in the rat; a variation with odor quality. Acta Physiol. Scand. 99:1977;270-280.
28. Vassar R., Ngai J., Axel R. Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell. 74:1993;309-318.
29. Vassar R., Chao S.K., Sitcheran R., Nunez J.M., Vosshall L.B., Axel R. Topographic organization of sensory projections to the olfactory bulb. Cell. 79:1994;981-991.
30. Youngentob S.L., Markert L.M., Mozell M.M., Hornung D.E. A method for establishing a five odorant identification confusion matrix task in rats. Physiol. Behav. 47:1990;1053-1059.
31. Youngentob S.L., Markert L.M., Hill T.W., Matyas E.P., Mozell M.M. Odorant identification in rats: an update. Physiol. Behav. 49:1991;1293-1296.
32. Youngentob S.L., Kent P.F., Sheehe P.R., Schwob J.E., Tzoumaka E. Mucosal inherent activity patterns in the rat: evidence from voltage-sensitive dyes. J. Neurophysiol. 73:1995;387-398.
33. Zhao H., Ivic L., Otaki J.M., Hashimoto M., Mikoshiba K., Firestein S. Functional expression of a mammalian odorant receptor. Science. 279:1998;237-242.