Spatially organized response zones in rat olfactory epithelium

Journal of Neurophysiology

Volumn 77, Issue 4, 1997, Pages 1950-1962

  Scott, John W ^a   Shannon, Donna E ^a   Charpentier, Jeff ^a   Davis, Lisa M ^a   Kaplan, Craig ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID ETHYL ESTER; CARVONE; HYDROCARBON; KETONE; LIMONENE; MENTHONE; PENTYL ACETATE; TERPINENE;

AIRFLOW; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTRODE; FACIAL BONE; MALE; NONHUMAN; ODOR; OLFACTORY DISCRIMINATION; OLFACTORY EPITHELIUM; OLFACTORY RECEPTOR; PRIORITY JOURNAL; RAT; SPATIAL ORIENTATION;

EID: 0030991124     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1997.77.4.1950     Document Type: Article

References (44)

1. ASTIC, L., SAUCIER, D., AND HOLLEY, A. Topographic relationships between olfactory receptor cells and glomerular foci in the rat olfactory bulb. Brain Res. 424: 144-152, 1987.
2. BUCK, L. B. Information coding in the vertebrate olfactory system. Annu. Rev. Neurosci. 19: 517-544, 1996.
3. BUCK, L. AND AXEL, R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65: 175-187, 1991.
4. EDWARDS, D. A., MATHER, R. A., AND DOOD, G. H. Spatial variation in response to odorants on the rat olfactory epithelium. Experientia 44: 208-211, 1988.
5. EZEH, P. I., SCOTT, J. W., AND DAVIS, L. M. Regional distribution of rat electroolfactogram. J. Neurophysiol. 73: 2207-2220, 1995.
6. FÜLLE, H., VASSAR, R., FOSTER, D. C., YANG, R., AXEL, R., AND GARBERS, D. L. A receptor guanylyl cyclase expressed specifically in olfactory neurons. Proc. Natl Acad. Sci. USA 92: 3571-3575, 1995.
7. GESTELAND, R. C. Initial events of the electro-olfactogram. Ann. NY Acad. Sci. 116: 440-447, 1964.
8. GETCHELL, T. B. Electrogenic sources of slow voltage transients recorded from frog olfactory epithelium. J. Neurophysiol. 37: 1115-1130, 1974.
9. GUTHRIE, K. M., ANDERSON, A. J., LEON, M., AND GALL, C. Odor-induced increases in c-fos mRNA expression reveal an anatomical "unit" for odor processing in olfactory bulb. Proc. Natl. Acad. Sci. USA 90: 3329-3333, 1993.
10. HAHN, I., SCHERER, P. W., AND MOZELL, M. M. A mass transport model of olfaction. J. Theor. Biol. 167: 115-128, 1994.
11. IMAMURA, K., MATAGA, N., AND MORI, K. Coding of odor molecules by mitral/tufted cells in rabbit olfactory bulb. I. Aliphatic compounds. J. Neurophysiol. 68: 1986-2002, 1992.
12. JASTREBOFF, P. J., PEDERSEN, P. E., GREER, C. A., STEWART, W. B., KAUER, J. S., BENSON, T. E., AND SHEPHERD, G. M. Specific olfactory receptor population projecting to identified glomeruli in the rat olfactory bulb. Proc. Natl Acad. Sci. USA 81: 5250-5254, 1984.
13. KAUER, J. S. AND MOULTON, D. G. Responses of olfactory bulb neurones to odour stimulation of small nasal areas in the salamander. J. Physiol. Lond. 243: 717-737, 1974.
14. KENT, P. F. AND MOZELL, M. M. The recording of odorant-induced mucosal activity patterns with a voltage-sensitive dye. J. Neurophysiol. 68: 1804-1819, 1992.
15. KENT, P. F., MOZELL, M. M., MURPHY, S. J., AND HORNUNG, D. E. The interaction of imposed and inherent olfactory mucosal activity patterns and their composite representation in a mammalian species using voltage-sensitive dyes. J. Neurosci. 16: 345-353, 1996.
16. LANCET, D., KAUER, J. S., AND GREER, C. A. High resolution 2-deoxyglucose localization in olfactory epithelium. Chem. Senses 6: 343-349, 1981.
17. LAZARD, D., ZUPKO, K., PORIA, Y., NEF, P., LAZAROVITS, J., HORN, S., KHEN, M., AND LANCET, D. Odorant signal termination by olfactory UDP glucuronosyl transferase. Nature Lond. 349: 790-793, 1991.
18. MACKAY-SIM, A. AND KESTEVEN, S. Topographic patterns of responsiveness to odorants in the rat olfactory epithelium. J. Neurophysiol 71: 150-160, 1994.
19. MORI, K. AND YOSHIHARA, Y. Molecular recognition and olfactory processing in the mammalian olfactory system. Prog. Neurobiol. 45: 585-619, 1995.
20. MOZELL, M. M., SHEEHE, P. R., HORNUNG, D. E., KENT, P. F., YOUNGENTOB, S. L., AND MURPHY, S. J. "Imposed" and "inherent" mucosal activity patterns. J. Gen. Physiol. 90: 625-650, 1987.
21. NEF, P., HERMANS-BORGMEYER, I., ARTIERES-PIN, H., BEASLEY, L., DIONNE, V. E., AND HEINEMANN, S. F. Spatial pattern of receptor expression in the olfactory epithelium. Proc. Natl. Acad. Sci. USA 89: 8948-8952, 1992.
22. ORONA, E., RAINER, E. C., AND SCOTT, J. W. Dendritic and axonal organization of mitral and tufted cells in the rat olfactory bulb. J. Comp. Neurol. 226: 346-356, 1984.
23. OTTOSON, D. Analysis of the electrical activity of the olfactory epithelium. Acta Physiol. Scand. Suppl. 122: 6-83, 1956.
24. PEDERSEN, P. E., JASTREBOFF, P. J., STEWART, W. B., AND SHEPHERD, G. M. Mapping of an olfactory receptor population that projects to a specific region in the rat olfactory bulb. J. Comp. Neurol. 250: 93-108, 1986.
25. PEVSNER, J., TRIFILETTI, R. R., STRITTMATTER, S. M., AND SNYDER, S. H. Isolation and characterization of an olfactory receptor protein for odorant pyrazine. Proc. Natl. Acad. Sci. USA 82: 3050-3054, 1985.
26. RAMA KRISHNA, N. S., GETCHELL, M. L., MARGOLIS, F. L., AND GETCHELL, T. V. Differential expression of vomeromodulin and odorant-binding protein, putative pheromone and odorant transporters, in the developing rat nasal chemosensory mucosae. J. Neurosci. Res. 40: 54-71, 1995.
27. RAMING, K., KRIEGER, J., STROTMANN, J., BOEKHOFF, I., KUBICK, S., BAUMSTARK, C., AND BREER, H. Cloning and expression of odorant receptors. Nature Lond. 361: 353-356, 1993.
28. RESSLER, K. J., SULLIVAN, S. L., AND BUCK, L. B. A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell 73: 597-609, 1993.
29. RESSLER, K. J., SULLIVAN, S. L., AND BUCK, L. B. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell 79: 1245-1255, 1994.
30. SATO, T., HIRONO, J., TONOIKE, M., AND TAKEBAYSHI, M. Tuning specificities to aliphatic odorants in mouse olfactory receptor neurons and their local distribution. J. Neurophysiol. 72: 2980-2989, 1994.
31. SCHOENFELD, T. A., CLANCY, A. N., FORBES, W. B., AND MACRIDES, F. The spatial organization of the peripheral olfactory system of the hamster. I. Receptor neuron projections to the main olfactory bulb. Brain Res. Bull. 183-210, 1994.
32. SCHOENFELD, T. A., MARCHAND, J. E., AND MACRIDES, T. Topographic organization of tufted cell axonal projections in the hamster main olfactory bulb: an intrabulbar associated system. J. Comp. Neurol. 235: 503-518, 1985.
33. SCOTT, J. W., DAVIS, L. M., SHANNON, D., AND KAPLAN, C. Relation of chemical structure to spatial distribution of sensory responses in rat olfactory epithelium. J. Neurophysiol. 75: 2036-2049, 1996.
34. SCOTT, J. W., KAPLAN, C., SHANNON, D., AND DAVIS, L. M. Distributions of electroolfactograms in rat correspond to olfactory receptor gene expression zones. Soc. Neurosci. Abstr. 21: 132, 1995.
35. SINGER, M. S., OLIVEIRA, L., VRIEND, G., AND SHEPHERD, G. M. Potential ligand-binding residues in rat olfactory receptors identified by correlated mutation analysis. Recept. Channels 3: 89-95, 1995.
36. SINGER, M. S. AND SHEPHERD, G. M. Molecular modeling of ligand-receptor interactions in the OR5 olfactory receptor. Neuroreport 5: 1297-1300, 1994.
37. STROTMANN, J., WANNER, I., HELFRICH, T., BECK, A., MEINKEN, C., KUBICK, S., AND BREER, H. Olfactory neurones expressing distinct odorant receptor subtypes are spatially segregated in the nasal neuroepithelium. Cell Tissue Res. 276: 429-438, 1994.
38. STROTMANN, J., WANNER, I., RAMING, K., AND BREER, H. Expression of odorant receptors in spatially restricted subsets of chemosensory neurones. Neuroreport 3: 1052-1056, 1992.
39. SULLIVAN, S. L., ADAMSON, M. C., RESSLER, K. J., KAZAK, C. A., AND BUCK, L. The chromosomal distribution of mouse odorant receptor genes. Proc. Natl Acad. Sci. USA 93: 884-888, 1996.
40. VASSAR, R., CHAO, S. K., SITCHERAN, R., NUÑEZ, J. M., VOSSHALL, L. B., AND AXEL, R. Topographic organization of sensory projections to the olfactory bulb. Cell 79: 981-991, 1994.
41. VASSAR, R., NGAI, J., AND AXEL, R. Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell 74: 309-318, 1993.
42. WANG, H.-W., WYSOCKI, C. J., AND GOLD, G. H. Induction of olfactory receptor sensitivity in mice. Science Wash. DC 260: 998-1000, 1993.
43. YOUNGENTOB, S. L. AND KENT, P. F. Enhancement of odorant-induced mucosal activity patterns in rats trained on an odorant identification task. Brain Res. 670: 82-88, 1995.
44. YOUNGENTOB, S. L., KENT, P. F., SHEEHE, P. R., SCHWOB, J. E., AND TZOUMAKA, E. Mucosal inherent activity patterns in the rat: evidence from voltage-sensitive dyes. J. Neurophysiol. 73: 387-398, 1995.