The human papillomavirus HPV2a E5 protein localizes to the Golgi apparatus and modulates signal transduction

Virology

Volumn 314, Issue 2, 2003, Pages 572-579

  Cartin, Walter ^a,b   Alonso, Angel ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b Inst Costaricense Contra el Cancer   (Costa Rica)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS PROTEIN;

ARTICLE; CELL MEMBRANE; ENZYME ACTIVATION; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENETIC TRANSFECTION; GOLGI COMPLEX; HUMAN; HUMAN CELL; INFECTION RISK; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKIN DEFECT; STRAIN DIFFERENCE; VIRAL SKIN DISEASE; VIRUS ENVELOPE; VIRUS GENE; VIRUS STRAIN; WART VIRUS;

HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 2; HUMAN PAPILLOMAVIRUS TYPE 2A; HUMAN PAPILLOMAVIRUS TYPES; PAPILLOMAVIRUS;

EID: 0141682655     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6822(03)00509-9     Document Type: Article

References (48)

1. Adler-Storthz K., Newland J.R., Tessin B.A., Yeudall W.A., Shillitoe E.J. Human papillomavirus type 2 DNA in oral verrucous carcinoma. J Oral Pathol. 15:1986;472-475.
2. Alonso A., Reed J. Modelling of the human papillomavirus Type 16 E5 Protein. Biochim. Biophys. Acta. 1601:2002;9-18.
3. Ashby A.D.M., Meagher L., Campo M.S., Finbow M.E. E5 transforming proteins of papillomaviruses do not disturb the activity of the vacuolar +H-ATPase. J. Gen. Virol. 82:2001;2353-2362.
4. Ashrafi G.H., Tsirimonaki E., Marchetti B., O'Brien P.M., Sibbet G.J., Andrei L., Campo M.S. Down-regulation of MHC class I by bovine papillomavirus E5 oncoprotein. Oncogene. 21:2001;248-259.
5. Auvinen E., Crusius K., Steuer B., Alonso A. The human papillomavirus E5 protein. Int. J. Oncol. 11:1997;1297-1304.
6. Bauer-Hofmann R., Borghouts C., Auvinen E., Bourda E., Rösl F., Alonso A. Genomic cloning and characterization of the non-occupied allele corresponding to the integration site of human papillomavirus type 16 DNA in the cervical carcinoma cell line SiHa. Virology. 217:1996;33-41.
7. Bouvard V., Matlashewski G., Gu Z.M., Storey A., Banks L. The human papillomavirus type 16 E5 gene cooperates with the E7 gene to stimulate proliferation of primary cells and increases viral gene expression. Virology. 203:1994;73-80.
8. Bubb V., McCance D.J., Schlegel R. DNA sequence of the HPV-16 E5 ORF and the structural conservation of its encoded protein. Virology. 163:1988;243-246.
9. Campo M.S. Animal models of papillomavirus pathogenesis. Virus Res. 89:2002;249-261.
10. Chan S.Y., Chew S.H., Egawa K., Grussendorf-Conen E.I., Honda Y., Rübben A., Tan K.C., Bernard H.U. Phylogenetic analysis of the human papillomavirus type 2 (HPV-2), HPV-27, and HPV-57 group, which is associated with common warts. Virology. 239:1997;296-302.
11. Chen S.-L., Huang C.H., Tsai T.C., Lu K.Y., Tsao Y.P. The regulation mechanism of c-jun and junB by human papillomavirus type 16 E5 oncoprotein. Arch. Virol. 141:1996;791-800.
12. Chen S.L., Tsai T.C., Han C.P., Tsao Y.P. Mutational analysis of human papillomavirus type II E5a oncoprotein. J. Virol. 70:1996;3502-3508.
13. Chow L.T., Nasseri M., Wolinsky S.M., Broker T.R. Human papillomavirus types 6 and II mRNAs from genital condylomata acuminata. J. Virol. 61:1987;2581-2588.
14. Conrad M., Bubb V.J., Schlegel R. The human papillomavirus type 6 and 16 E5 proteins are membrane-associated proteins which associate with the 16-kilodalton pore-forming protein. J. Virol. 67:1993;6170-6178.
15. Conrad M., Goldstein D., Andresson T., Schlegel R. The E5 protein of HPV-6, but not HPV-16 associates efficiently with cellular growth factor receptors. Virology. 200:1994;796-800.
16. Cromme F.V., Meijer C.J., Snijders P.J., Uyterlinde A., Kenemans P., Helmerhorst T., Stern P.L., van den Brule A.J., Walboomers J.M. Analysis of MHC cless I and II expression in relation to presence of HPV genotypes in premalignant and malignant cervical lesions. Br. J. Cancer. 67:1993;1372-1380.
17. Crusius K., Auvinen E., Alonso A. Enhancement of EGF- and PMA-mediated MAP Kinase activation in cells expressing the human papillomavirus type 16 E5 protein. Oncogene. 15:1997;1437-1444.
18. Crusius K., Auvinen E., Steuer B., Gaissert H., Alonso A. The human papillomavirus type 16 E5-protein modulates ligand-dependent activation of the EGF receptor family in the human epithelial cell line HaCaT. Exp. Cell Res. 241:1998;76-83.
19. Crusius K., Rodríguez I., Alonso A. The human papillomavirus type 16 E5 protein modulates ERK1/2 and p38 MAP kinase activation by an EGFR-independent process in stressed human keratinocytes. Virus Genes. 20:2000;65-69.
20. DiMaio D., Mattoon D. Mechanisms of cell transformation by papillomavirus E5 proteins. Oncogene. 20:2001;7866-7873.
21. Faulkner-Valle G., Banks L. The human papillomavirus (HPV)-6 and HPV-16 E5 proteins co-operate with HPV-16 E7 in the transformation of primary rodent cells. J. Gen. Virol. 76:1995;1239-1245.
22. Gu Z., Matlashewski G. Effect of human papillomavirus type 16 oncogenes on MAP kinase activation. J. Virol. 69:1995;8051-8056.
23. Hirsch-Behnam A., Delius H., de Villiers E.M. A comparative sequence analysis of two human papillomavirus (HPV) types 2a and 57. Virus Res. 18:1990;81-98.
24. Hwang E.S., Nottoli T., DiMaio D. The HPV16 E5 protein expression, detection, and stable complex formation with transmembrane proteins in COS cells . Virology. 211:1995;227-233.
25. Kabsch K., Alonso A. The human papillomavirus type 16 E5 protein impairs TRAIL- and FasL-mediated apoptosis in human keratinocytes by different mechanisms. J. Virol. 76:2002;12162-12172.
26. Keefe M., al-Ghamdi A., Coggon D., Maitland N.J., Egger P., Keefe C.J., Carey A., Sanders C.M. Cutaneous warts in butchers. Br. J. Dermatol. 130:1994;9-14.
27. Leechanachai P., Banks L., Moreau F., Matlashewski G. The E5 gene from human papillomavirus type 16 is an oncogene which enhances growth factor-mediated signal transduction to the nucleus. Oncogene. 7:1992;19-25.
28. Leptak C., Ramon y., Cajal S., Kulke R., Horwitz B.H., Riese D.J. II, Dotto G.P., DiMaio D. Tumorigenic transformation of murine keratinocytes by the E5 genes of bovine papillomavirus type 1 and human papillomavirus type 16. J. Virol. 65:1991;7078-7083.
29. Lu S., Syjänen K., Havu V.K., Syrjänen S. Expression of PCNA is associated with the presence of HPV DNA in skin warts. Arch. Dermatol. Res. 289:1996;35-39.
30. Marchetti B., Ashrafi G.H., Tsirimonaki E., O'Brien P.M., Campo M.S. The bovine papillomavirus oncoprotein E5 retains MHC class I molecules in the Golgi apparatus and prevents their transport to the cell surface. Oncogene. 21:2002;7808-7816.
31. Martinez-Menarguez J.A., Geuze H.J., Ballesta J. Identification of two types of beta-COP vesicles in the Golgi complex of rat spermatides. Eur. J. Cell Biol. 71:1996;137-143.
32. Obalek S., Misiewicz J., Jablonska S., Favre M., Orth G. Childhood condyloma acuminatum association with genital and cutaneous human papillomaviruses . Pediatr. Dermatol. 10:1993;101-106.
33. Oelze I., Kartenbeck J., Crusius K., Alonso A. Human papillomavirus type 16 E5 protein affects cell-cell communication in an epithelial cell line. J. Virol. 69:1995;4489-4494.
34. Oetke C., Auvinen E., Pawlita M., Alonso A. Human papillomavirus type 16 E5 protein localizes to the Golgi apparatus but does not effect cellular glycosylation. Arch. Virol. 145:2000;2183-2191.
35. Orth G., Favre M., Croissant O. Characterization of a new type of human papillomavirus that causes skin warts. J. Virol. 24:1977;108-120.
36. Pim D., Collins M., Banks L. Human papillomavirus type 16 E5 gene stimulates the transforming activity of the epidermal growth factor receptor. Oncogene. 7:1992;27-32.
37. Rebai N., Malissen B. Structural and genetic analyses of HLA class I molecules using monoclonal xenoantibodies. Tissue Antigens. 22:1983;107-117.
38. Ritz U., Momburg F., Pilch H., Huber C., Maeurer M.J., Seliger B. Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma. Int. J. Oncol. 19:2001;1211-1220.
39. Ryu K.S., Lee Y.S., Kim B.K., Park Y.G., Kim Y.W., Hur S.Y., Kim T.E., Kim I.K., Kim J.W. Alterations of HLA class I and II antigen expression in preinvasive, invasive and metastatic cervical cancer. Exp. Mol. Med. 33:2001;136-144.
40. Schlegel R., Wade-Glass M., Rabson M.S., Yang Y.Z. The E5 transforming gene of bovine papillomavirus encodes a small, hydrophobic polypeptide. Science. 233:1986;464-467.
41. Schwarz E., Freese U.K., Gissmann L., Mayer W., Roggenbuck B., Stremlau A., zur Hausen H. Structure and transcription of human papillomavirus sequences in cervical carcinoma cells. Nature. 314:1985;111-114.
42. Stoler M.H., Rhodes C.R., Withbeck A., Wolinsky S.M., Chow L.T., Broker T.R. Human papillomavirus type 16 and 18 gene expression in cervical neoplasias. Hum. Pathol. 23:1992;117-128.
43. Straight S.W., Hinkle P.M., Jewers R.J., McCance D.J. The E5 oncoprotein of human papillomavirus type 16 transforms fibroblasts and effects the down-regulation of the epidermal growth factor receptor in keratinocytes. J. Virol. 67:1993;4521-4532.
44. Straight S.W., Herman B., McCance D.J. The E5 oncoprotein of human papillomavirus type 16 inhibits the acidification of endosomes in human keratinocytes. J. Virol. 69:1995;3185-3192.
45. Surti T., Klein O., Schheim K., DiMaio D., Smith S.O. Structural models of the bovine papillomavirus E5 protein. Proteins. 33:1998;601-612.
46. WafI/SdiI/CipI gene expression in fibroblasts and keratinocytes. J. Virol. 70:1996;7535-7539.
47. Zhang B., Spandau D.F., Roman A. E5 protein of human papillomavirus type 16 protects human foreskin keratinocytes from UV B-irradiation-induced apoptosis. J. Virol. 76:2002;220-231.
48. zur Hausen H. Papillomaviruses and cancer from basic studies to clinical application . Nature Rev. Cancer. 2:2002;342-350.